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Modeling the dynamics of probability distributions from time-dependent data samples is a fundamental problem in many fields, including digital health. The goal is to analyze how the distribution of a biomarker, such as glucose, changes over…

Machine Learning · Statistics 2025-09-18 Antonio Álvarez-López , Marcos Matabuena

In this work we establish a link between two different phenomena that were studied in a large and growing number of biological, composite and soft media: the diffusion in compartmentalized environment and the Brownian yet non-Gaussian…

Statistical Mechanics · Physics 2020-08-05 Jakub Ślęzak , Stanislav Burov

Cells sense environmental signals and transmit information intracellularly through changes in the abundance of molecular components. Such molecular abundances can be measured in single cells and exhibit significant heterogeneity in clonal…

Quantitative Methods · Quantitative Biology 2024-09-27 Raymond Fan , Andreas Hilfinger

Probabilistic modeling provides the capability to represent and manipulate uncertainty in data, models, predictions and decisions. We are concerned with the problem of learning probabilistic models of dynamical systems from measured data.…

Computation · Statistics 2018-03-14 Thomas B. Schön , Andreas Svensson , Lawrence Murray , Fredrik Lindsten

This note presents a simulation method for investigating the relationship between porosity and particle size distribution in porous media characterization. The method simulates particle packing based on particle size distributions,…

Soft Condensed Matter · Physics 2024-09-25 Yuhe Wang

Nonlinear reaction-diffusion systems admit a wide variety of spatiotemporal patterns or structures. In this lecture, we point out that there is certain advantage in studying discrete arrays, namely cellular neural/nonlinear networks (CNNs),…

Pattern Formation and Solitons · Physics 2007-05-23 M. Lakshmanan , P. Muruganandam

We have previously reported a Bayesian algorithm for determining the coordinates of points in three-dimensional space from uncertain constraints. This method is useful in the determination of biological molecular structure. It is limited,…

Artificial Intelligence · Computer Science 2013-02-28 Russ B. Altman , Cheng C. Chen , William B. Poland , Jaswinder Pal Singh

The study of wave propagation in chains of anharmonic periodic systems is of fundamental importance to understand the response of dynamical absorbers of vibrations and acoustic metamaterials working in nonlinear regime. Here, we derive an…

Geophysics · Physics 2019-10-23 R. Zivieri , F. Garescì , B. Azzerboni , M. Chiappini , G. Finocchio

Learning a distribution conditional on a set of discrete-valued features is a commonly encountered task. This becomes more challenging with a high-dimensional feature set when there is the possibility of interaction between the features. In…

Machine Learning · Statistics 2013-05-01 David C. Kessler , Jack Taylor , David B. Dunson

We consider a kinetic equation describing evolution of a particle distribution function in a system with nonlinear wave-particle interactions (trappings into a resonance and nonlinear scatterings). We study properties of its solutions and…

Plasma Physics · Physics 2019-05-22 A. V. Artemyev , A. I. Neishtadt , A. A. Vasiliev

Computer simulations can aid in understanding how collective materials properties emerge from interactions between simple constituents. Here, we introduce a coarse-grained model that enables simulation of networks of actin filaments, myosin…

Biological Physics · Physics 2018-12-07 Simon L. Freedman , Shiladitya Banerjee , Glen M. Hocky , Aaron R. Dinner

In this work we demonstrate the efficacy of neural networks in the characterization of dispersive media. We also develop a neural network to make predictions for input probe pulses which propagate through a nonlinear dispersive medium,…

Optics · Physics 2019-12-02 Sanjaya Lohani , Erin M. Knutson , Wenlei Zhang , Ryan T. Glasser

A physical scenario accounting for the existence of size-limited submicrometric domains in cell membranes is proposed. It is based on the numerical investigation of the counterpart, in lipidic membranes where proteins are diffusing, of the…

Soft Condensed Matter · Physics 2015-06-25 Nicolas Destainville

The mechanism of diffusing diffusivity predicts that, in environments where the diffusivity changes gradually, the displacement distribution becomes non-Gaussian, even though the mean-squared displacement (MSD) grows linearly with time.…

Statistical Mechanics · Physics 2017-10-18 Mpumelelo Matse , Mykyta V. Chubynsky , John Bechhoefer

An experimental study of current fluctuations through a tunable transmission barrier, a quantum point contact, are reported. We measure the probability distribution function of transmitted charge with precision sufficient to extract the…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 G. Gershon , Yu. Bomze , E. V. Sukhorukov , M. Reznikov

Identifying a coupled dynamical system out of many plausible candidates, each of which could serve as the underlying generator of some observed measurements, is a profoundly ill posed problem that commonly arises when modelling real world…

Neurons and Cognition · Quantitative Biology 2019-09-17 Amirhossein Jafarian , Peter Zeidman , Vladimir Litvak , Karl Friston

Non-reciprocal systems exhibit diverse dynamical phases whose character depends on the type and degree of non-reciprocity. In this study, we theoretically investigate dynamical structures in a mixture of non-reciprocally aligning polar…

Soft Condensed Matter · Physics 2024-12-20 Kim L. Kreienkamp , Sabine H. L. Klapp

Active cellular transport is a fundamental mechanism for protein and vesicle delivery, cell cycle and molecular degradation. Viruses can hijack the transport system and use it to reach the nucleus. Most transport processes consist of…

Quantitative Methods · Quantitative Biology 2009-11-13 T. Lagache , D. Holcman

Quantum transport in a class of nonlinear extensions of the Rudner-Levitov model is numerically studied in this paper. We show that the quantization of the mean displacement, which embodies the quantum coherence and the topological…

Quantum Physics · Physics 2022-05-25 Lei Du , Jin-Hui Wu , M. Artoni , G. C. La Rocca

Intracellular transport of organelles is fundamental to cell function and health. The mounting evidence suggests that this transport is in fact anomalous. However, the reasons for the anomaly is still under debate. We examined experimental…

Subcellular Processes · Quantitative Biology 2018-12-10 Nickolay Korabel , Thomas A. Waigh , Sergei Fedotov , Viki J. Allan
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