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Magnetic Resonance Imaging (MRI) is one of the most flexible and powerful medical imaging modalities. This flexibility does however come at a cost; MRI images acquired at different sites and with different parameters exhibit significant…

The use of machine-learning in neuroimaging offers new perspectives in early diagnosis and prognosis of brain diseases. Although such multivariate methods can capture complex relationships in the data, traditional approaches provide…

Recent deep learning approaches focus on improving quantitative scores of dedicated benchmarks, and therefore only reduce the observation-related (aleatoric) uncertainty. However, the model-immanent (epistemic) uncertainty is less…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Dominik Narnhofer , Alexander Effland , Erich Kobler , Kerstin Hammernik , Florian Knoll , Thomas Pock

In performative learning, the data distribution reacts to the deployed model - for example, because strategic users adapt their features to game it - which creates a more complex dynamic than in classical supervised learning. One should…

Machine Learning · Computer Science 2025-10-15 Edwige Cyffers , Alireza Mirrokni , Marco Mondelli

In this paper we extend the state-of-the-art filtered backprojection (FBP) method with application of the concept of Total Variation regularization. We compare the performance of the new algorithm with the most common form of regularizing…

Functional magnetic resonance imaging (fMRI) analysis faces significant challenges due to limited dataset sizes and domain variability between studies. Traditional self-supervised learning methods inspired by computer vision often rely on…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Jakub Frac , Alexander Schmatz , Qiang Li , Guido Van Wingen , Shujian Yu

Multivariate Pattern (MVP) classification holds enormous potential for decoding visual stimuli in the human brain by employing task-based fMRI data sets. There is a wide range of challenges in the MVP techniques, i.e. decreasing noise and…

Machine Learning · Statistics 2016-12-28 Muhammad Yousefnezhad , Daoqiang Zhang

In this paper we introduce the notion of second-order total generalized variation (TGV) regularization for manifold-valued data in a discrete setting. We provide an axiomatic approach to formalize reasonable generalizations of TGV to the…

Numerical Analysis · Mathematics 2018-09-17 K. Bredies , M. Holler , M. Storath , A. Weinmann

Uncertainty quantification is vital for decision-making and risk assessment in machine learning. Mean-variance regression models, which predict both a mean and residual noise for each data point, provide a simple approach to uncertainty…

Machine Learning · Statistics 2025-12-01 Eliot Wong-Toi , Alex Boyd , Vincent Fortuin , Stephan Mandt

In computational neuroscience, it is important to estimate well the proportion of signal variance in the total variance of neural activity measurements. This explainable variance measure helps neuroscientists assess the adequacy of…

Applications · Statistics 2014-01-14 Yuval Benjamini , Bin Yu

This paper proposes a computationally efficient algorithm to address the Full-Waveform Inversion (FWI) problem with a Total Variation (TV) constraint, designed to accurately reconstruct subsurface properties from seismic data. FWI, as an…

Signal Processing · Electrical Eng. & Systems 2025-01-15 Yudai Inada , Shingo Takemoto , Shunsuke Ono

In recent years,the application of deep learning in task functional Magnetic Resonance Imaging (tfMRI) decoding has led to significant advancements. However,most studies remain constrained by assumption of temporal stationarity in neural…

Machine Learning · Computer Science 2025-03-05 Yueyang Wu , Sinan Yang , Yanming Wang , Jiajie He , Muhammad Mohsin Pathan , Bensheng Qiu , Xiaoxiao Wang

Regularization plays a crucial role in reliably utilizing imaging systems for scientific and medical investigations. It helps to stabilize the process of computationally undoing any degradation caused by physical limitations of the imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-05-26 Manu Ghulyani , Deepak G Skariah , Muthuvel Arigovindan

The 3-D total variation (3DTV) is a powerful regularization term, which encodes the local smoothness prior structure underlying a hyper-spectral image (HSI), for general HSI processing tasks. This term is calculated by assuming identical…

Computer Vision and Pattern Recognition · Computer Science 2018-09-19 Jiangjun Peng , Qi Xie , Qian Zhao , Yao Wang , Deyu Meng , Yee Leung

We consider the problem of reconstructing 2D images from randomly under-sampled confocal microscopy samples. The well known and widely celebrated total variation regularization, which is the L1 norm of derivatives, turns out to be…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Bibin Francis , Manoj Mathew , Muthuvel Arigovindan

Combining Functional MRI (fMRI) data across different subjects and datasets is crucial for many neuroscience tasks. Relying solely on shared anatomy for brain-to-brain mapping is inadequate. Existing functional transformation methods thus…

Neurons and Cognition · Quantitative Biology 2025-03-18 Navve Wasserman , Roman Beliy , Roy Urbach , Michal Irani

Variational regularization models are one of the popular and efficient approaches for image restoration. The regularization functional in the model carries prior knowledge about the image to be restored. The prior knowledge, in particular…

Optimization and Control · Mathematics 2021-02-09 Yan-ran Li , Raymond H. F. Chan , Lixin Shen , Xiaosheng Zhuang

We derive a new margin-based regularization formulation, termed multi-margin regularization (MMR), for deep neural networks (DNNs). The MMR is inspired by principles that were applied in margin analysis of shallow linear classifiers, e.g.,…

Machine Learning · Computer Science 2020-09-15 Berry Weinstein , Shai Fine , Yacov Hel-Or

Background: Brain maturation and aging involve significant microstructural changes, resulting in functional and cognitive alterations. Quantitative MRI (qMRI) can measure this evolution, distinguishing the physiological effects of normal…

Image normalization is a building block in medical image analysis. Conventional approaches are customarily utilized on a per-dataset basis. This strategy, however, prevents the current normalization algorithms from fully exploiting the…

Machine Learning · Computer Science 2020-10-06 Pierre-Luc Delisle , Benoit Anctil-Robitaille , Christian Desrosiers , Herve Lombaert
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