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Recent methods have been developed to map single-cell lineage statistics to population growth. Because population growth selects for exponentially rare phenotypes, these methods inherently depend on sampling large deviations from finite…

Statistical Mechanics · Physics 2025-01-16 Trevor GrandPre , Ethan Levien , Ariel Amir

We reformulate the eigenvalue problem for the selection--mutation equilibrium distribution in the case of a haploid asexually reproduced population in the form of an equation for an unknown probability generating function of this…

Populations and Evolution · Quantitative Biology 2015-01-21 Yuri S. Semenov , Artem S. Novozhilov

We consider a stochastic individual-based model for the evolution of a haploid, asexually reproducing population. The space of possible traits is given by the vertices of a (possibly directed) finite graph $G=(V,E)$. The evolution of the…

Probability · Mathematics 2020-03-10 Loren Coquille , Anna Kraut , Charline Smadi

The first chapter concerns monotype population models. We first study general birth and death processes and we give non-explosion and extinction criteria, moment computations and a pathwise representation. We then show how different scales…

Probability · Mathematics 2017-07-06 Vincent Bansaye , Sylvie Méléard

This study conducts a comparative analysis of stochastic and deterministic models to better understand the dynamics of the HIV epidemic across genders. By incorporating gender-specific transmission probabilities and treatment uptake rates,…

Populations and Evolution · Quantitative Biology 2025-01-30 Nuzhat Nuari Khan Rivu , Md Kamrujjaman , Shohel Ahmed

The nonequilibrium stationary state of an exclusive genetic switch is considered. The model comprises two competing species and a single binding site which, when bound to by a protein of one species, causes the other species to be…

Statistical Mechanics · Physics 2013-01-24 J. Venegas-Ortiz , M. R. Evans

The long-term growth rate of populations in varying environments quantifies the evolutionary value of processing the information that biological individuals inherit from their ancestors and acquire from their environment. Previous models…

Populations and Evolution · Quantitative Biology 2021-06-30 Anton S Zadorin , Olivier Rivoire

The aim of this paper, triggered by some discussions in the astrophysics community raised by astro-ph/0508529, is to introduce the issue of `fits' from a probabilistic perspective (also known as Bayesian), with special attention to the…

Data Analysis, Statistics and Probability · Physics 2007-05-23 G. D'Agostini

We compare and contrast the long-time dynamical properties of two individual-based models of biological coevolution. Selection occurs via multispecies, stochastic population dynamics with reproduction probabilities that depend nonlinearly…

Populations and Evolution · Quantitative Biology 2011-11-10 Per Arne Rikvold

The goal of this work is to propose a finite population counterpart to Eigen's model, which incorporates stochastic effects. We consider a Moran model describing the evolution of a population of size $m$ of chromosomes of length $\ell$ over…

Populations and Evolution · Quantitative Biology 2012-10-25 Raphaël Cerf

We consider a two-species simple exclusion process on a periodic lattice. We use the method of matched asymptotics to derive evolution equations for the two population densities in the dilute regime, namely a cross-diffusion system of…

Mathematical Physics · Physics 2023-01-25 James Mason , Robert L Jack , Maria Bruna

We consider a general, neutral, dynamical model of biodiversity. Individuals have i.i.d. lifetime durations, which are not necessarily exponentially distributed, and each individual gives birth independently at constant rate \lambda. We…

Populations and Evolution · Quantitative Biology 2010-09-02 Amaury Lambert

Understanding patterns of selectively neutral genetic variation is essential in order to model deviations from neutrality, caused for example by different forms of selection. Best understood is neutral genetic variation at a single locus,…

Populations and Evolution · Quantitative Biology 2012-06-13 E. Schaper , A. Eriksson , M. Rafajlovic , S. Sagitov , B. Mehlig

As artificial intelligence systems (AIs) become increasingly produced by recursive self-improvement, a form of evolution may emerge, with the traits of AI systems shaped by the success of earlier AIs in designing and propagating their…

Artificial Intelligence · Computer Science 2026-04-14 Kenneth D Harris

In statistical problems, a set of parameterized probability distributions is used to estimate the true probability distribution. If Fisher information matrix at the true distribution is singular, then it has been left unknown what we can…

Machine Learning · Computer Science 2009-01-19 Sumio Watanabe

Disentangling the processes leading populations to extinction is a major topic in ecology and conservation biology. The difficulty to find a mate in many species is one of these processes. Here, we investigate the impact of…

Populations and Evolution · Quantitative Biology 2012-01-05 Sylvain Billiard , Viet Chi Tran

We study the evolution of the probability density of an asexual, one locus population under natural selection and random evolution. This evolution is governed by a Fokker-Planck equation with degenerate coefficients on the boundaries,…

Analysis of PDEs · Mathematics 2013-01-21 Fabio A. C. C. Chalub , Max O. Souza

We study a class of evolution models, where the breeding process involves an arbitrary exchangeable process, allowing for mutations to appear. The population size $n$ is fixed, hence after breeding, selection is applied. Individuals are…

Probability · Mathematics 2022-05-03 Daniela Bertacchi , Juri Lember , Fabio Zucca

We consider the evolution of an asexually reproducing population in an uncorrelated random fitness landscape in the limit of infinite genome size, which implies that each mutation generates a new fitness value drawn from a probability…

Populations and Evolution · Quantitative Biology 2009-11-13 Su-Chan Park , Joachim Krug

We consider the classic problem of estimating T, the total number of species in a population, from repeated counts in a simple random sample. We look first at the Chao-Lee estimator: we initially show that such estimator can be obtained by…

Applications · Statistics 2008-04-09 L. Cecconi , A. Gandolfi , C. C. A. Sastri
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