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Melanoma is one of the most aggressive forms of skin cancer, causing a large proportion of skin cancer deaths. However, melanoma diagnoses by pathologists shows low interrater reliability. As melanoma is a cancer of the melanocyte, there is…

Quantitative Methods · Quantitative Biology 2024-03-15 Mikio Tada , Ursula E. Lang , Iwei Yeh , Elizabeth S. Keiser , Maria L. Wei , Michael J. Keiser

Microscopy images contain rich information about how cells respond to perturbations, making them essential to applications like drug screening. To quantify images, researchers often use representation extraction methods, and recent years…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Emre Hayir , Lorin Crawford , Alex X. Lu

Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Steve Tsham Mpinda Ataky , Alessandro Lameiras Koerich

Texture is the term used to characterize the surface of a given object or phenomenon and is an important feature used in image processing and pattern recognition. Our aim is to compare various Texture analyzing methods and compare the…

Computer Vision and Pattern Recognition · Computer Science 2012-10-30 Pooja Maknikar

Our goal is to bridge human and machine intelligence in melanoma detection. We develop a classification system exploiting a combination of visual pre-processing, deep learning, and ensembling for providing explanations to experts and to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Ellák Somfai , Benjámin Baffy , Kristian Fenech , Changlu Guo , Rita Hosszú , Dorina Korózs , Fabrizio Nunnari , Marcell Pólik , Daniel Sonntag , Attila Ulbert , András Lőrincz

Melanoma is one of the ten most common cancers in the US. Early detection is crucial for survival, but often the cancer is diagnosed in the fatal stage. Deep learning has the potential to improve cancer detection rates, but its…

Computer Vision and Pattern Recognition · Computer Science 2019-05-16 Devansh Bisla , Anna Choromanska , Jennifer A. Stein , David Polsky , Russell Berman

Pathomics is a recent approach that offers rich quantitative features beyond what black-box deep learning can provide, supporting more reproducible and explainable biomarkers in digital pathology. However, many derived features (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Yuechen Yang , Junlin Guo , Ruining Deng , Junchao Zhu , Zhengyi Lu , Chongyu Qu , Yanfan Zhu , Xingyi Guo , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

We present a new annotated microscopic cellular image dataset to improve the effectiveness of machine learning methods for cellular image analysis. Cell counting is an important step in cell analysis. Typically, domain experts manually…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Abdurahman Ali Mohammed , Catherine Fonder , Donald S. Sakaguchi , Wallapak Tavanapong , Surya K. Mallapragada , Azeez Idris

Vascular calcification is implicated as an important factor in major adverse cardiovascular events (MACE), including heart attack and stroke. A controversy remains over how to integrate the diverse forms of vascular calcification into…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Mehdi Ramezanpour , Anne M. Robertson , Yasutaka Tobe , Xiaowei Jia , Juan R. Cebral

Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

Recent advances in digital pathology have led to the need for Histopathology Image Retrieval (HIR) systems that search through databases of biopsy images to find similar cases to a given query image. These HIR systems allow pathologists to…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Shalev Lifshitz , Abtin Riasatian , H. R. Tizhoosh

As the number of patients with heart failure increases, machine learning (ML) has garnered attention in cardiomyopathy diagnosis, driven by the shortage of pathologists. However, endomyocardial biopsy specimens are often small sample size…

Machine Learning · Computer Science 2025-10-23 Masaya Mori , Yuto Omae , Yutaka Koyama , Kazuyuki Hara , Jun Toyotani , Yasuo Okumura , Hiroyuki Hao

We propose in this paper a texture-invariant 2D keypoints descriptor specifically designed for matching preoperative Magnetic Resonance (MR) images with intraoperative Ultrasound (US) images. We introduce a matching-by-synthesis strategy,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Hassan Rasheed , Reuben Dorent , Maximilian Fehrentz , Tina Kapur , William M. Wells , Alexandra Golby , Sarah Frisken , Julia A. Schnabel , Nazim Haouchine

Digital pathology has emerged as a transformative approach to tissue analysis, offering unprecedented opportunities for objective, quantitative assessment of histopathological features. However, the complexity of implementing artificial…

Quantitative Methods · Quantitative Biology 2025-09-17 Noor Shaker , Mohamed AbouZleikha , Nuha Shaker

In order to utilize identification to the best extent, we need robust and fast algorithms and systems to process the data. Having palmprint as a reliable and unique characteristic of every person, we extract and use its features based on…

Computer Vision and Pattern Recognition · Computer Science 2015-02-13 Shervin Minaee , AmirAli Abdolrashidi

The deployment of Machine Learning models intraoperatively for tissue characterisation can assist decision making and guide safe tumour resections. For image classification models, pixel attribution methods are popular to infer…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Alfie Roddan , Chi Xu , Serine Ajlouni , Irini Kakaletri , Patra Charalampaki , Stamatia Giannarou

Querying the content of images, video, and other non-textual data sources requires expensive content extraction methods. Modern extraction techniques are based on deep convolutional neural networks (CNNs) and can classify objects within…

Databases · Computer Science 2019-04-23 Michael R. Anderson , Michael Cafarella , German Ros , Thomas F. Wenisch

Accurate nuclei detection and classification are fundamental to computational pathology, yet existing approaches are hindered by reliance on detailed expert annotations and insufficient use of tissue context. We present Tissue-Aware Nuclei…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Kesi Xu , Eleni Chiou , Ali Varamesh , Laura Acqualagna , Nasir Rajpoot

Background: Single-cell RNA sequencing (scRNA-seq) yields valuable insights about gene expression and gives critical information about complex tissue cellular composition. In the analysis of single-cell RNA sequencing, the annotations of…

Genomics · Quantitative Biology 2023-03-29 Xiaowen Cao , Li Xing , Elham Majd , Hua He , Junhua Gu , Xuekui Zhang

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao