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This paper proposes methods for likelihood-based inference in multivariate linear regressions when the correlation matrix of the responses is separable; that is, it has a Kronecker product structure, but the variances are unrestricted. The…

Computation · Statistics 2026-04-16 Karl Oskar Ekvall

Longitudinal imaging studies have moved to the forefront of medical research due to their ability to characterize spatio-temporal features of biological structures across the lifespan. Credible models of the correlations in longitudinal…

Applications · Statistics 2015-02-04 Sean L. Simpson , Lloyd J. Edwards , Martin A. Styner , Keith E. Muller

In clinical studies with paired organs, binary outcomes often exhibit intra-subject correlation and may include a mixture of unilateral and bilateral observations. Under Donner's constant correlation model, we develop three likelihood-based…

Methodology · Statistics 2025-10-22 Jia Zhou , Chang-Xing Ma

A separable covariance model for a random matrix provides a parsimonious description of the covariances among the rows and among the columns of the matrix, and permits likelihood-based inference with a very small sample size. However, in…

Methodology · Statistics 2022-07-27 Peter Hoff , Andrew McCormack , Anru R. Zhang

Intraclass correlation in bilateral data has been investigated in recent decades with various statistical methods. In practice, stratifying bilateral data by some control variables will provide more sophisticated statistical results to…

Methodology · Statistics 2023-03-24 Wanqing Tian , Chang-Xing Ma

The matrix-variate normal distribution is a popular model for high-dimensional transposable data because it decomposes the dependence structure of the random matrix into the Kronecker product of two covariance matrices: one for each of the…

Methodology · Statistics 2014-11-11 Anestis Touloumis , John Marioni , Simon Tavaré

In this paper, we develop modified versions of the likelihood ratio test for multivariate heteroskedastic errors-in-variables regression models. The error terms are allowed to follow a multivariate distribution in the elliptical class of…

Statistics Theory · Mathematics 2013-03-18 Tatiane F. N. Melo , Silvia L. P. Ferrari , Alexandre G. Patriota

We develop a higher order generalization of the LQ decomposition and show that this decomposition plays an important role in likelihood-based estimation and testing for separable, or Kronecker structured, covariance models, such as the…

Statistics Theory · Mathematics 2018-06-20 David C. Gerard , Peter D. Hoff

We propose a Kronecker product model for correlation or covariance matrices in the large dimensional case. The number of parameters of the model increases logarithmically with the dimension of the matrix. We propose a minimum distance (MD)…

Statistics Theory · Mathematics 2019-05-20 Christian M. Hafner , Oliver B. Linton , Haihan Tang

Analyzing the covariance structure of data is a fundamental task of statistics. While this task is simple for low-dimensional observations, it becomes challenging for more intricate objects, such as multivariate functions. Here, the…

Methodology · Statistics 2023-01-12 Holger Dette , Gauthier Dierickx , Tim Kutta

A factor model with a break in its factor loadings is observationally equivalent to a model without changes in the loadings but a change in the variance of its factors. This effectively transforms a structural change problem of high…

Econometrics · Economics 2023-12-06 Jushan Bai , Jiangtao Duan , Xu Han

Human mortality data sets can be expressed as multiway data arrays, the dimensions of which correspond to categories by which mortality rates are reported, such as age, sex, country and year. Regression models for such data typically assume…

Methodology · Statistics 2014-04-15 Bailey K. Fosdick , Peter D. Hoff

Testing covariance structure is of importance in many areas of statistical analysis, such as microarray analysis and signal processing. Conventional tests for finite-dimensional covariance cannot be applied to high-dimensional data in…

Statistics Theory · Mathematics 2013-10-31 Rongmao Zhang , Liang Peng , Ruodu Wang

Motivated by the Kronecker product approximation technique, we have developed a very simple method to assess the inseparability of bipartite quantum systems, which is based on a realigned matrix constructed from the density matrix. For any…

Quantum Physics · Physics 2007-05-23 Kai Chen , Ling-An Wu

In subgroup analysis, testing the existence of a subgroup with a differential treatment effect serves as protection against spurious subgroup discovery. Despite its importance, this hypothesis testing possesses a complicated nature:…

Statistics Theory · Mathematics 2025-03-21 Shota Takeishi

We study the problem of multiple hypothesis testing for multidimensional data when inter-correlations are present. The problem of multiple comparisons is common in many applications. When the data is multivariate and correlated, existing…

Statistics Theory · Mathematics 2015-06-02 Mahdis Azadbakhsh , Xin Gao , Hanna Jankowski

We give a general unified method that can be used for $L_1$ {\em closeness testing} of a wide range of univariate structured distribution families. More specifically, we design a sample optimal and computationally efficient algorithm for…

Data Structures and Algorithms · Computer Science 2015-08-25 Ilias Diakonikolas , Daniel M. Kane , Vladimir Nikishkin

Kronecker product covariance structure provides an efficient way to modeling the inter-correlations of matrix-variate data. In this paper, we propose testing statistics for Kronecker product covariance matrix based on linear spectral…

Statistics Theory · Mathematics 2022-05-02 Long Yu , Jiahui Xie , Wang Zhou

In this paper, we use the method of modified signed log-likelihood ratio test for the problem of testing the equality of correlation coefficients in two independent bivariate normal distributions. We compare this method with two other…

Methodology · Statistics 2016-06-01 M. R. Kazemi , A. A. Jafari

Mixed linear models are commonly used in repeated measures studies. They account for the dependence amongst observations obtained from the same experimental unit. Oftentimes, the number of observations is small, and it is thus important to…

Methodology · Statistics 2011-08-05 Tatiane F. N. Melo , Silvia L. P. Ferrari , Francisco Cribari-Neto
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