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The last decade has witnessed a surge of theoretical and computational models to describe the dynamics of complex gene regulatory networks, and how these interactions can give rise to multistable and heterogeneous cell populations. As the…

Molecular Networks · Quantitative Biology 2023-06-28 Federico Bocci , Dongya Jia , Qing Nie , Mohit Kumar Jolly , Jose Onuchic

In this paper, we propose a mean-field model which attempts to bridge the gap between random Boolean networks and more realistic stochastic modeling of genetic regulatory networks. The main idea of the model is to replace all regulatory…

Quantitative Methods · Quantitative Biology 2009-11-13 M. Andrecut , S. A. Kauffman

Artificial and natural neural network models are a new toolkit which could be potentially have been used for clarifying of complex brain functions. To attend this goal, such models need to be neurobiologically realistic. However, although…

Neurons and Cognition · Quantitative Biology 2022-07-08 Arsenii Onuchin

Random functional-linked types of neural networks (RFLNNs), e.g., the extreme learning machine (ELM) and broad learning system (BLS), which avoid suffering from a time-consuming training process, offer an alternative way of learning in deep…

Machine Learning · Computer Science 2023-04-04 Guang-Yong Chen , Yong-Hang Yu , Min Gan , C. L. Philip Chen , Wenzhong Guo

Neural networks (NNs) whose subnetworks implement reusable functions are expected to offer numerous advantages, including compositionality through efficient recombination of functional building blocks, interpretability, preventing…

Neural and Evolutionary Computing · Computer Science 2021-03-09 Róbert Csordás , Sjoerd van Steenkiste , Jürgen Schmidhuber

Correlation Networks (CNs) inherently suffer from redundant information in their network topology. Bayesian Networks (BNs), on the other hand, include only non-redundant information (from a probabilistic perspective) resulting in a sparse…

Data Analysis, Statistics and Probability · Physics 2020-11-03 Catharina Graafland , José M. Gutiérrez , Juan M. López , Diego Pazó , Miguel A. Rodríguez

In this paper we made a review of some papers about probabilistic regulatory networks (PRN), in particular we introduce our concept of homomorphisms of PRN with an example of projection of a regulatory network to a smaller one. We apply the…

Cell Behavior · Quantitative Biology 2007-08-20 Maria A. Avino-Diaz

We compare asynchronous vs. synchronous update of discrete dynamical networks and find that a simple time delay in the nodes may induce a reproducible deterministic dynamics even in the case of asynchronous update in random order. In…

Molecular Networks · Quantitative Biology 2007-05-23 Konstantin Klemm , Stefan Bornholdt

In this paper we study homomorphisms of Probabilistic Regulatory Gene Networks(PRN) introduced in arXiv:math.DS/0603289 v1 13 Mar 2006. The model PRN is a natural generalization of the Probabilistic Boolean Networks (PBN), introduced by I.…

Dynamical Systems · Mathematics 2007-05-23 Maria A. Avino-Diaz

Stochastic processes that involve the creation of objects and relations over time are widespread, but relatively poorly studied. For example, accurate fault diagnosis in factory assembly processes requires inferring the probabilities of…

Artificial Intelligence · Computer Science 2011-09-13 P. Domingos , S. Sanghai , D. Weld

Conditional generative models are capable of using contextual information as input to create new imaginative outputs. Conditional Restricted Boltzmann Machines (CRBMs) are one class of conditional generative models that have proven to be…

Machine Learning · Computer Science 2023-05-16 Alex H. Lang , Anton D. Loukianov , Charles K. Fisher

This paper investigates the stabilization of probabilistic Boolean networks (PBNs) via a novel pinning control strategy based on network structure. In a PBN, the evolution equation of each gene switches among a collection of candidate…

Systems and Control · Electrical Eng. & Systems 2020-10-26 Lin Lin , Jinde Cao , Jianquan Lu , Jie Zhong

Complex networks have recently attracted much interest due to their prevalence in nature and our daily lives [1, 2]. A critical property of a network is its resilience to random breakdown and failure [3-6], typically studied as a…

Physics and Society · Physics 2016-01-08 James P. Bagrow , Sune Lehmann , Yong-Yeol Ahn

Effective control of biological systems can often be achieved through the control of a surprisingly small number of distinct variables. We bring clarity to such results using the formalism of Boolean dynamical networks, analyzing the…

Molecular Networks · Quantitative Biology 2021-09-13 Enrico Borriello , Bryan C. Daniels

We investigate dynamical properties of a quantum generalization of classical reversible Boolean networks. The state of each node is encoded as a single qubit, and classical Boolean logic operations are supplemented by controlled bit-flip…

Quantum Physics · Physics 2022-01-05 Lucas Kluge , Joshua E. S. Socolar , Eckehard Schöll

Recurrent neural networks (RNNs) are non-linear dynamic systems. Previous work believes that RNN may suffer from the phenomenon of chaos, where the system is sensitive to initial states and unpredictable in the long run. In this paper,…

Computation and Language · Computer Science 2020-04-30 Pourya Vakilipourtakalou , Lili Mou

A common problem of classical neural network architectures is that additional information or expert knowledge cannot be naturally integrated into the learning process. To overcome this limitation, we propose a two-step approach consisting…

Machine Learning · Computer Science 2024-06-17 Florian Seiffarth

Models of random phylogenetic networks have been used since the inception of the field, but the introduction and rigorous study of mathematically tractable models is a much more recent topic that has gained momentum in the last 5 years.…

Populations and Evolution · Quantitative Biology 2024-11-20 François Bienvenu

The critical boundaries separating ordered from chaotic behavior in randomly wired S-state networks are calculated. These networks are a natural generalization of random Boolean nets and are proposed as on extended approach to genetic…

adap-org · Physics 2007-05-23 Ricard V. Sole , Bartolo Luque , Stuart Kauffman

Boolean networks are an important class of computational models for molecular interaction networks. Boolean canalization, a type of hierarchical clustering of the inputs of a Boolean function, has been extensively studied in the context of…

Molecular Networks · Quantitative Biology 2024-07-09 David Murrugarra , Elena S. Dimitrova