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The primitive model describes ions by point charges with an additional hard-core interaction. In classical density-functional theory the mean-field electrostatic contribution can be obtained from the first order of a functional perturbation…

Soft Condensed Matter · Physics 2022-04-06 Moritz Bültmann , Andreas Härtel

Electrical neural signalling typically takes place at the time-scale of milliseconds, and is typically modeled using the cable equation. This is a good approximation for processes when ionic concentrations vary little during the time course…

Cell Behavior · Quantitative Biology 2014-03-05 Geir Halnes , Ivar Østby , Klas H. Pettersen , Stig W. Omholt , Gaute T. Einevoll

The electrical properties of extracellular space around neurons are important to understand the genesis of extracellular potentials, as well as for localizing neuronal activity from extracellular recordings. However, the exact nature of…

The extracellular space has an ambiguous role in neuroscience. It is present in every physiologically relevant system and often used as a measurement site in experimental recordings, but it has received subordinate attention compared to the…

Neurons and Cognition · Quantitative Biology 2017-05-02 Jurgis Pods

Using an effective-field-theory (nonlinear sigma model) description of interacting electrons in a disordered metal ring enclosing magnetic flux, we calculate the moments of the persistent current distribution, in terms of interacting…

Mesoscale and Nanoscale Physics · Physics 2009-10-30 H. J. Bussemaker , T. R. Kirkpatrick

The ability of discrete-time nonlinear recurrent neural networks to store time-varying small input signals is investigated by mean-field theory. The combination of a small input strength and mean-field assumptions makes it possible to…

Adaptation and Self-Organizing Systems · Physics 2019-12-25 Taichi Haruna , Kohei Nakajima

Dynamic Causal Modeling (DCM) is a Bayesian framework for inferring on hidden (latent) neuronal states, based on measurements of brain activity. Since its introduction in 2003 for functional magnetic resonance imaging data, DCM has been…

Quantitative Methods · Quantitative Biology 2021-04-08 Inês Pereira , Stefan Frässle , Jakob Heinzle , Dario Schöbi , Cao Tri Do , Moritz Gruber , Klaas E. Stephan

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

We develop analytical models of optical-field electron tunneling from the edge and surface of two-dimensional (2D) materials, including the effects of reduced dimensionality, non-parabolic energy dispersion, band anisotropy, quasi-time…

Mesoscale and Nanoscale Physics · Physics 2023-03-21 Yi Luo , Yee Sin Ang , L. K. Ang

We present a complete mean field theory for a balanced state of a simple model of an orientation hypercolumn. The theory is complemented by a description of a numerical procedure for solving the mean-field equations quantitatively. With our…

Neurons and Cognition · Quantitative Biology 2007-05-23 A. Lerchner , G. Sterner , J. Hertz , M. Ahmadi

Accurate electromagnetic modeling of the head of a subject is of main interest in the fields of source reconstruction and brain stimulation. Those processes rely heavily on the quality of the model and, even though the geometry of the…

Medical Physics · Physics 2022-02-15 Martin Grignard , Christophe Geuzaine , Christophe Phillips

Magnetoencephalographic (MEG) measurements record magnetic fields generated from neurons while information is being processed in the brain. The inverse problem of identifying sources of biomagnetic fields and deducing their intensities from…

Neurons and Cognition · Quantitative Biology 2009-11-11 Hung-I Pai , Chih-Yuan Tseng , HC Lee

Cable theory has been developed over the last decades, usually assuming that the extracellular space around membranes is a perfect resistor. However, extracellular media may display more complex electrical properties due to various…

Neurons and Cognition · Quantitative Biology 2013-09-19 Claude Bedard , Alain Destexhe

Signals recorded from neurons with extracellular planar sensors have a wide range of waveforms and amplitudes. This variety is a result of different physical conditions affecting the ion currents through a cellular membrane. The…

This paper develops a quantitatively accurate first-principles description for the frequency and the linewidth of collective electronic excitations in inhomogeneous weakly disordered systems. A finite linewidth in general has intrinsic and…

Mesoscale and Nanoscale Physics · Physics 2009-11-07 C. A. Ullrich , G. Vignale

Training deep neural networks with stochastic gradient descent (SGD) can often achieve zero training loss on real-world tasks although the optimization landscape is known to be highly non-convex. To understand the success of SGD for…

Machine Learning · Statistics 2020-06-15 Yiping Lu , Chao Ma , Yulong Lu , Jianfeng Lu , Lexing Ying

In studies of the brain and the nervous system, extracellular signals - as measured by local field potentials (LFPs) or electroencephalography (EEG) - are of capital importance, as they allow to simultaneously obtain data from multiple…

Neurons and Cognition · Quantitative Biology 2019-06-10 Jurgis Pods

We rigorously prove a central limit theorem for neural network models with a single hidden layer. The central limit theorem is proven in the asymptotic regime of simultaneously (A) large numbers of hidden units and (B) large numbers of…

Probability · Mathematics 2019-06-04 Justin Sirignano , Konstantinos Spiliopoulos

Measurements of electric potentials from neural activity have played a key role in neuroscience for almost a century, and simulations of neural activity is an important tool for understanding such measurements. Volume conductor (VC) theory…

Neurons and Cognition · Quantitative Biology 2021-05-04 Torbjørn V. Ness , Geir Halnes , Solveig Næss , Klas H. Pettersen , Gaute T. Einevoll

Sampling from unnormalized densities presents a fundamental challenge with wide-ranging applications, from posterior inference to molecular dynamics simulations. Continuous flow-based neural samplers offer a promising approach, learning a…

Machine Learning · Computer Science 2025-07-22 Wuhao Chen , Zijing Ou , Yingzhen Li