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Despite their dominance in vision and language, deep neural networks often underperform relative to tree-based models on tabular data. To bridge this gap, we incorporate five key inductive biases into deep learning: robustness to irrelevant…
The Maximum (Minimum) Leaf Spanning Tree problem asks for a spanning tree with the largest (smallest) number of leaves. As spanning trees are often computed using graph search algorithms, it is natural to restrict this problem to the set of…
Extreme-scale data centers are the backbone of next-generation computing, enabling breakthroughs in science, artificial intelligence, and global innovation through unprecedented processing power and scalability. This work examines…
Data approximation is essential in fields such as geometric design, numerical PDEs, and curve modeling. Moving Least Squares (MLS) is a widely used method for data fitting; however, its accuracy degrades in the presence of discontinuities,…
Given a distance matrix consisting of pairwise distances between species, a distance-based phylogenetic reconstruction method returns a tree metric or equidistant tree metric (ultrametric) that best fits the data. We investigate…
Phylogenetic networks extend phylogenetic trees to allow for modeling reticulate evolutionary processes such as hybridization. They take the shape of a rooted, directed, acyclic graph, and when parameterized with evolutionary parameters,…
Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species that evolved from a common ancestor. When phylogenetic trees…
How do phylogenetic reconstruction algorithms go astray when they return incorrect trees? This simple question has not been answered in detail, even for maximum parsimony (MP), the simplest phylogenetic criterion. Understanding MP has…
This paper considers generalized least squares (GLS) estimation for linear panel data models. By estimating the large error covariance matrix consistently, the proposed feasible GLS (FGLS) estimator is more efficient than the ordinary least…
Time series data in the retail world are particularly rich in terms of dimensionality, and these dimensions can be aggregated in groups or hierarchies. Valuable information is nested in these complex structures, which helps to predict the…
We consider the problem of estimating a sparse multi-response regression function, with an application to expression quantitative trait locus (eQTL) mapping, where the goal is to discover genetic variations that influence gene-expression…
Few-shot learning (FSL) techniques seek to learn the underlying patterns in data using fewer samples, analogous to how humans learn from limited experience. In this limited-data scenario, the challenges associated with deep neural networks,…
Phylogenetic networks are necessary to represent the tree of life expanded by edges to represent events such as horizontal gene transfers, hybridizations or gene flow. Not all species follow the paradigm of vertical inheritance of their…
Tree rearrangements such as Nearest Neighbor Interchange (NNI) and Subtree Prune and Regraft (SPR) are commonly used to explore phylogenetic treespace. Computing distances based on them, however, is often intractable, so the efficiently…
Partial Least Squares (PLS) is a widely used method for data integration, designed to extract latent components shared across paired high-dimensional datasets. Despite decades of practical success, a precise theoretical understanding of its…
Biological data including gene expression data are generally high-dimensional and require efficient, generalizable, and scalable machine-learning methods to discover their complex nonlinear patterns. The recent advances in machine learning…
Recent work on mode connectivity in the loss landscape of deep neural networks has demonstrated that the locus of (sub-)optimal weight vectors lies on continuous paths. In this work, we train a neural network that serves as a hypernetwork,…
This paper presents a minimalist neural regression network as an aggregate of independent identical regression blocks that are trained simultaneously. Moreover, it introduces a new multiplicative parameter, shared by all the neural units of…
Evolutionary methods have long been useful for analysis and explanation in genetics, biology, ecology, and related fields. In this work, we extend these methods to neural networks, specifically large language models (LLMs), to better…
In many modern data sets, High dimension low sample size (HDLSS) data is prevalent in many fields of studies. There has been an increased focus recently on using machine learning and statistical methods to mine valuable information out of…