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Phylogenetic trees are a central tool in understanding evolution. They are typically inferred from sequence data, and capture evolutionary relationships through time. It is essential to be able to compare trees from different data sources…

Populations and Evolution · Quantitative Biology 2017-10-31 Michelle Kendall , Caroline Colijn

Classification of gene trees is an important task both in the analysis of multi-locus phylogenetic data, and assessment of the convergence of Markov Chain Monte Carlo (MCMC) analyses used in Bayesian phylogenetic tree reconstruction. The…

Combinatorics · Mathematics 2024-06-10 Georgios Aliatimis , Ruriko Yoshida , Burak Boyaci , James A. Grant

Dissimilarity measures for (possibly weighted) phylogenetic trees based on the comparison of their vectors of path lengths between pairs of taxa, have been present in the systematics literature since the early seventies. But, as far as…

Populations and Evolution · Quantitative Biology 2008-07-06 Gabriel Cardona , Merce Llabres , Francesc Rossello , Gabriel Valiente

Phylogenetic diversity is a measure for describing how much of an evolutionary tree is spanned by a subset of species. If one applies this to the (unknown) subset of current species that will still be present at some future time, then this…

Subcellular Processes · Quantitative Biology 2009-09-29 Beata Faller , Fabio Pardi , Mike Steel

Balanced minimum evolution is a distance-based criterion for the reconstruction of phylogenetic trees. Several algorithms exist to find the optimal tree with respect to this criterion. One approach is to minimize a certain linear functional…

Combinatorics · Mathematics 2019-05-23 Cassandra Durell , Stefan Forcey

Phylogenetic networks are used to represent the evolutionary history of species. They are versatile when compared to traditional phylogenetic trees, as they capture more complex evolutionary events such as hybridization and horizontal gene…

Combinatorics · Mathematics 2023-05-18 Shunsuke Maeda , Yusuke Kaneko , Hideaki Muramatsu , Yukihiro Murakami , Momoko Hayamizu

A phylogenetic tree shows the evolutionary relationships among species. Internal nodes of the tree represent speciation events and leaf nodes correspond to species. A goal of phylogenetics is to combine such trees into larger trees, called…

Artificial Intelligence · Computer Science 2014-01-16 Neil C. A. Moore , Patrick Prosser

Phylogenetic tree reconstruction is traditionally based on multiple sequence alignments (MSAs) and heavily depends on the validity of this information bottleneck. With increasing sequence divergence, the quality of MSAs decays quickly.…

Populations and Evolution · Quantitative Biology 2011-01-11 Roland F. Schwarz , William Fletcher , Frank Förster , Benjamin Merget , Matthias Wolf , Jörg Schultz , Florian Markowetz

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

We propose networked exponential families to jointly leverage the information in the topology as well as the attributes (features) of networked data points. Networked exponential families are a flexible probabilistic model for heterogeneous…

Machine Learning · Computer Science 2019-09-26 Alexander Jung

Recent work used importance sampling ideas for better variational bounds on likelihoods. We clarify the applicability of these ideas to pure probabilistic inference, by showing the resulting Importance Weighted Variational Inference (IWVI)…

Machine Learning · Computer Science 2018-10-30 Justin Domke , Daniel Sheldon

We present an Evolutionary Placement Algorithm (EPA) for the rapid assignment of sequence fragments (short reads) to branches of a given phylogenetic tree under the Maximum Likelihood (ML) model. The accuracy of the algorithm is evaluated…

Genomics · Quantitative Biology 2009-11-17 S. A. Berger , A. Stamatakis

A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

Populations and Evolution · Quantitative Biology 2025-09-03 S M Rafiuddin

Optimising probabilistic models is a well-studied field in statistics. However, its connection with the training of generative models remains largely under-explored. In this paper, we show that the evolution of time-varying generative…

Machine Learning · Statistics 2025-06-16 Song Liu , Leyang Wang , Yakun Wang

Phylogenetic trees are the fundamental mathematical representation of evolutionary processes in biology. They are also objects of interest in pure mathematics, such as algebraic geometry and combinatorics, due to their discrete geometry.…

Metric Geometry · Mathematics 2022-07-01 Anthea Monod , Bo Lin , Ruriko Yoshida , Qiwen Kang

The search for similarity and dissimilarity measures on phylogenetic trees has been motivated by the computation of consensus trees, the search by similarity in phylogenetic databases, and the assessment of clustering results in…

Populations and Evolution · Quantitative Biology 2011-11-09 Francesc Rossello , Gabriel Valiente

Construction of phylogenetic trees has traditionally focused on binary trees where all species appear on leaves, a problem for which numerous efficient solutions have been developed. Certain application domains though, such as viral…

Data Structures and Algorithms · Computer Science 2016-11-01 Dimitris Papamichail , Angela Huang , Andrew Miller , Edward Kennedy , Jan-Lucas Ott , Georgios Papamichail

The reliability of a phylogenetic inference method from genomic sequence data is ensured by its statistical consistency. Bayesian inference methods produce a sample of phylogenetic trees from the posterior distribution given sequence data.…

Metric Geometry · Mathematics 2016-06-10 Alex Gavryushkin , Alexei J. Drummond

High dimensional data reduction techniques are provided by using partial least squares within deep learning. Our framework provides a nonlinear extension of PLS together with a disciplined approach to feature selection and architecture…

Methodology · Statistics 2021-06-29 Nicholas Polson , Vadim Sokolov , Jianeng Xu

This paper deals with some nonlinear problems which exponential and biexponential decays are involved in. A proof of the quasiconvexity of the error function in some of these problems of optimization is presented. This proof is restricted…

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