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In observational studies, instrumental variable (IV) methods are commonly applied when there exists some unmeasured covariates. In Mendelian Randomization (MR), constructing an allele score by using many single nucleotide polymorphisms…

Methodology · Statistics 2022-08-22 Shunichiro Orihara

We introduce a flexible empirical Bayes approach for fitting Bayesian generalized linear models. Specifically, we adopt a novel mean-field variational inference (VI) method and the prior is estimated within the VI algorithm, making the…

Machine Learning · Statistics 2026-01-30 Dongyue Xie , Wanrong Zhu , Matthew Stephens

This paper considers quantile model with grouped explanatory variables. In order to have the sparsity of the parameter groups but also the sparsity between two successive groups of variables, we propose and study an adaptive fused group…

Statistics Theory · Mathematics 2016-07-20 Gabriela Ciuperca

We consider high-dimensional inference for potentially misspecified Cox proportional hazard models based on low dimensional results by Lin and Wei [1989]. A de-sparsified Lasso estimator is proposed based on the log partial likelihood…

Statistics Theory · Mathematics 2018-11-02 Shengchun Kong , Zhuqing Yu , Xianyang Zhang , Guang Cheng

We develop a technique to design efficiently computable estimators for sparse linear regression in the simultaneous presence of two adversaries: oblivious and adaptive. We design several robust algorithms that outperform the state of the…

Machine Learning · Computer Science 2024-11-01 Chih-Hung Liu , Gleb Novikov

Exogenous heterogeneity, for example, in the form of instrumental variables can help us learn a system's underlying causal structure and predict the outcome of unseen intervention experiments. In this paper, we consider linear models in…

Methodology · Statistics 2024-10-21 Niklas Pfister , Jonas Peters

Recent results have proven the minimax optimality of LASSO and related algorithms for noisy linear regression. However, these results tend to rely on variance estimators that are inefficient or optimizations that are slower than LASSO…

Statistics Theory · Mathematics 2019-03-18 Christopher Kennedy , Rachel Ward

This work considers variational Bayesian inference as an inexpensive and scalable alternative to a fully Bayesian approach in the context of sparsity-promoting priors. In particular, the priors considered arise from scale mixtures of Normal…

Computation · Statistics 2022-11-01 Kody J. H. Law , Vitaly Zankin

We propose new inference tools for forward stepwise regression, least angle regression, and the lasso. Assuming a Gaussian model for the observation vector y, we first describe a general scheme to perform valid inference after any selection…

Methodology · Statistics 2015-10-13 Ryan J. Tibshirani , Jonathan Taylor , Richard Lockhart , Robert Tibshirani

The multivariate regression interpretation of the Gaussian chain graph model simultaneously parametrizes (i) the direct effects of $p$ predictors on $q$ outcomes and (ii) the residual partial covariances between pairs of outcomes. We…

Methodology · Statistics 2024-03-28 Yunyi Shen , Claudia Solís-Lemus , Sameer K. Deshpande

Traditional instrumental variable (IV) estimators face a fundamental constraint: they can only accommodate as many endogenous treatment variables as available instruments. This limitation becomes particularly challenging in settings where…

Machine Learning · Computer Science 2025-06-25 Shiangyi Lin , Hui Lan , Vasilis Syrgkanis

This paper contributes to the literature on treatment effects estimation with machine learning inspired methods by studying the performance of different estimators based on the Lasso. Building on recent work in the field of high-dimensional…

Econometrics · Economics 2018-05-15 Michael Zimmert

In this paper we derive an online estimator for sparse parameter vectors which, unlike the LASSO approach, does not require the tuning of any hyperparameters. The algorithm is based on a covariance matching approach and is equivalent to a…

Statistics Theory · Mathematics 2015-06-04 Dave Zachariah , Petre Stoica

We consider a problem of model selection in high-dimensional binary Markov random fields. The usefulness of the Ising model in studying systems of complex interactions has been confirmed in many papers. The main drawback of this model is…

Methodology · Statistics 2018-12-11 Błażej Miasojedow , Wojciech Rejchel

The linear instrumental variable (IV) model is widely used in observational studies, yet its validity hinges on strong assumptions. Classical specification tests such as the Sargan-Hansen J test are limited to overidentified settings and…

Methodology · Statistics 2026-04-21 Cyrill Scheidegger , Malte Londschien , Peter Bühlmann

In this paper, we consider the Group Lasso estimator of the covariance matrix of a stochastic process corrupted by an additive noise. We propose to estimate the covariance matrix in a high-dimensional setting under the assumption that the…

Statistics Theory · Mathematics 2011-10-26 Jérémie Bigot , Rolando Biscay , Jean-Michel Loubes , Lilian Muniz Alvarez

In this paper we present the SPICE approach for sparse parameter estimation in a framework that unifies it with other hyperparameter-free methods, namely LIKES, SLIM and IAA. Specifically, we show how the latter methods can be interpreted…

Statistics Theory · Mathematics 2015-05-12 Petre Stoica , Dave Zachariah , Jian Li

Mixtures of matrix Gaussian distributions provide a probabilistic framework for clustering continuous matrix-variate data, which are becoming increasingly prevalent in various fields. Despite its widespread adoption and successful…

Computation · Statistics 2023-07-21 Andrea Cappozzo , Alessandro Casa , Michael Fop

The instrumental variable method is widely used in the health and social sciences for identification and estimation of causal effects in the presence of potentially unmeasured confounding. In order to improve efficiency, multiple…

Methodology · Statistics 2022-04-19 Baoluo Sun , Zhonghua Liu , Eric Tchetgen Tchetgen

We propose a self-tuning $\sqrt{\mathrm {Lasso}}$ method that simultaneously resolves three important practical problems in high-dimensional regression analysis, namely it handles the unknown scale, heteroscedasticity and (drastic)…

Methodology · Statistics 2014-05-27 Alexandre Belloni , Victor Chernozhukov , Lie Wang