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A pressing scientific challenge is to understand how brains work. Of particular interest is the neocortex,the part of the brain that is especially large in humans, capable of handling a wide variety of tasks including visual, auditory,…

Neural and Evolutionary Computing · Computer Science 2016-09-03 Peter U. Diehl , Matthew Cook

Learning is thought to occur by localized, experience-induced changes in the strength of synaptic connections between neurons. Recent work has shown that activity-dependent changes at one connection can affect changes at others (crosstalk).…

Neurons and Cognition · Quantitative Biology 2008-02-22 Kingsley J. A. Cox , Paul R. Adams

Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables. It has been previously proposed that non-linear…

Neurons and Cognition · Quantitative Biology 2016-04-25 Jeff Hawkins , Subutai Ahmad

Theoretical models of neuronal function consider different mechanisms through which networks learn, classify and discern inputs. A central focus of these models is to understand how associations are established amongst neurons, in order to…

Neurons and Cognition · Quantitative Biology 2015-05-19 Harold P. de Vladar , Eörs Szathmáry

Learning in the brain is local and unsupervised (Hebbian). We derive the foundations of an effective human language model inspired by these microscopic constraints. It has two parts: (1) a hierarchy of neurons which learns to tokenize words…

Computation and Language · Computer Science 2025-03-05 P. Myles Eugenio

The cortex learns to make associations between stimuli and spiking activity which supports behaviour. It does this by adjusting synaptic weights. The complexity of these transformations implies that synapses have to change without access to…

Neurons and Cognition · Quantitative Biology 2019-11-04 Johnatan Aljadeff , James D'amour , Rachel E. Field , Robert C. Froemke , Claudia Clopath

In the traditional understanding of the neocortex, sensory information flows up a hierarchy of regions, with each level processing increasingly complex features. Information also flows down the hierarchy via a different set of connections.…

Neurons and Cognition · Quantitative Biology 2025-07-09 Jeff Hawkins , Niels Leadholm , Viviane Clay

Recent work on Long Term Potentiation in brain slices shows that Hebb's rule is not completely synapse-specific, probably due to intersynapse diffusion of calcium or other factors. We extend the classical Oja unsupervised model of learning…

Neurons and Cognition · Quantitative Biology 2008-01-15 Anca Radulescu , Kingsley Cox , Paul Adams

How does the neocortex learn and develop the foundations of all our high-level cognitive abilities? We present a comprehensive framework spanning biological, computational, and cognitive levels, with a clear theoretical continuity between…

Neurons and Cognition · Quantitative Biology 2017-09-15 Randall C. O'Reilly , Dean R. Wyatte , John Rohrlich

Neuromorphic computing with spiking neural networks is promising for energy-efficient artificial intelligence (AI) applications. However, different from humans who continually learn different tasks in a lifetime, neural network models…

Neural and Evolutionary Computing · Computer Science 2024-02-20 Mingqing Xiao , Qingyan Meng , Zongpeng Zhang , Di He , Zhouchen Lin

Hebbian learning is a biological principle that intuitively describes how neurons adapt their connections through repeated stimuli. However, when applied to machine learning, it suffers serious issues due to the unconstrained updates of the…

Machine Learning · Computer Science 2025-10-23 Shikuang Deng , Jiayuan Zhang , Yuhang Wu , Ting Chen , Shi Gu

We introduce a model of generalized Hebbian learning and retrieval in oscillatory neural networks modeling cortical areas such as hippocampus and olfactory cortex. Recent experiments have shown that synaptic plasticity depends on spike…

Disordered Systems and Neural Networks · Physics 2007-05-23 Silvia Scarpetta , Zhaoping Li , John Hertz

A model of sensory information processing is presented. The model assumes that learning of internal (hidden) generative models, which can predict the future and evaluate the precision of that prediction, is of central importance for…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Andras Lorincz

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Neurons and Cognition · Quantitative Biology 2022-05-17 Ivan Y. Tyukin , Alexander N. Gorban , Carlos Calvo , Julia Makarova , Valeri A. Makarov

A model of the columnar functional organization of neocortical association areas is studied. The neuronal network is composed of many Hebbian autoassociators, or modules, each of which interacts with a relatively small number of the others.…

Disordered Systems and Neural Networks · Physics 2020-05-14 Carlo Fulvi Mari

The theory of computational complexity is used to underpin a recent model of neocortical sensory processing. We argue that encoding into reconstruction networks is appealing for communicating agents using Hebbian learning and working on…

Neurons and Cognition · Quantitative Biology 2007-05-23 Andras Lorincz

The integration of neural representations in the two hemispheres is an important problem in neuroscience. Recent experiments revealed that odor responses in cortical neurons driven by separate stimulation of the two nostrils are highly…

Neurons and Cognition · Quantitative Biology 2024-12-17 Bo Liu , Shanshan Qin , Venkatesh Murthy , Yuhai Tu

Memory is a key component of biological neural systems that enables the retention of information over a huge range of temporal scales, ranging from hundreds of milliseconds up to years. While Hebbian plasticity is believed to play a pivotal…

Neural and Evolutionary Computing · Computer Science 2022-05-24 Thomas Limbacher , Ozan Özdenizci , Robert Legenstein

The aim of the present paper is to study the effects of Hebbian learning in random recurrent neural networks with biological connectivity, i.e. sparse connections and separate populations of excitatory and inhibitory neurons. We furthermore…

Neurons and Cognition · Quantitative Biology 2007-06-19 Benoit Siri , Mathias Quoy , Bruno Delord , Bruno Cessac , Hugues Berry

Cognitive ageing seems to be a story of global degradation. As one ages there are a number of physical, chemical and biological changes that take place. Therefore it is logical to assume that the brain is no exception to this phenomenon.…

Adaptation and Self-Organizing Systems · Physics 2014-08-07 Sakyasingha Dasgupta
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