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The recently measured yeast transcriptional network is analyzed in terms of simplified Boolean network models, with the aim of determining feasible rule structures, given the requirement of stable solutions of the generated Boolean…

Molecular Networks · Quantitative Biology 2009-11-10 Stuart Kauffman , Carsten Peterson , Björn Samuelsson , Carl Troein

The goal of this tutorial is to promote interest in the study of random Boolean networks (RBNs). These can be very interesting models, since one does not have to assume any functionality or particular connectivity of the networks to study…

Adaptation and Self-Organizing Systems · Physics 2009-09-29 Carlos Gershenson

Circuits provide ideal platforms of topological phases and matter, yet the study of topological circuits in the strongly nonlinear regime, has been lacking. We propose and experimentally demonstrate strongly nonlinear topological phases and…

Mesoscale and Nanoscale Physics · Physics 2023-07-03 Jijie Tang , Fangyuan Ma , Feng Li , Honglian Guo , Di Zhou

Coherent, large scale dynamics in many nonequilibrium physical, biological, or information transport networks are driven by small-scale local energy input. Here, we introduce and explore an analytically tractable nonlinear model for…

Biological Physics · Physics 2017-07-19 Aden Forrow , Francis G. Woodhouse , Jörn Dunkel

Identification of attractors, that is, stable states and sustained oscillations, is an important step in the analysis of Boolean models and exploration of potential variants. We describe an approach to the search for asynchronous cyclic…

Discrete Mathematics · Computer Science 2024-03-29 Elisa Tonello , Loïc Paulevé

This article is set in the field of regulation networks modeled by discrete dynamical systems. It focuses on Boolean automata networks. In such networks, there are many ways to update the states of every element. When this is done…

Discrete Mathematics · Computer Science 2015-03-19 Mathilde Noual

Boolean networks have been used in a variety of settings, as models for general complex systems as well as models of specific systems in diverse fields, such as biology, engineering, and computer science. Traditionally, their properties as…

Dynamical Systems · Mathematics 2024-02-02 Matthew Wheeler , Claus Kadelka , Alan Veliz-Cuba , David Murrugarra , Reinhard Laubenbacher

Continuous-time systems with switch-like behaviour occur in chemical kinetics, gene regulatory networks and neural networks. Networks with hard switching, as a limiting case of smooth sigmoidal switching, retain the richest possible range…

Dynamical Systems · Mathematics 2019-05-10 Roderick Edwards

This work aims to improve generalization and interpretability of dynamical systems by recovering the underlying lower-dimensional latent states and their time evolutions. Previous work on disentangled representation learning within the…

Machine Learning · Computer Science 2024-06-07 Çağlar Hızlı , Çağatay Yıldız , Matthias Bethge , ST John , Pekka Marttinen

Dynamical phase transitions are defined as non-analytic points of the large deviation function of current fluctuations. We show that for boundary driven systems, many dynamical phase transitions can be identified using the geometrical…

Statistical Mechanics · Physics 2017-12-13 Ohad Shpielberg

Boolean networks model finite discrete dynamical systems with complex behaviours. The state of each component is determined by a Boolean function of the state of (a subset of) the components of the network. This paper addresses the…

Artificial Intelligence · Computer Science 2020-02-28 Stéphanie Chevalier , Christine Froidevaux , Loïc Paulevé , Andrei Zinovyev

Linear thresholding systems have been used as a model of neural activation and have more recently been proposed as a model of gene activation. Deterministic linear thresholding systems can be turned into non-deterministic systems by the…

Neurons and Cognition · Quantitative Biology 2023-11-23 Anna Laddach , Michael Shapiro

In spite of the recent interest and advances in linear controllability of complex networks, controlling nonlinear network dynamics remains to be an outstanding problem. We develop an experimentally feasible control framework for nonlinear…

Molecular Networks · Quantitative Biology 2015-09-24 Le-Zhi Wang , Ri-Qi Su , Zi-Gang Huang , Xiao Wang , Wenxu Wang , Celso Grebogi , Ying-Cheng Lai

In the last decade, there has been a growing body of literature addressing the utilization of complex network methods for the characterization of dynamical systems based on time series. While both nonlinear time series analysis and complex…

Data Analysis, Statistics and Probability · Physics 2025-02-03 Yong Zou , Reik V. Donner , Norbert Marwan , Jonathan F. Donges , Jürgen Kurths

We consider a nonlinear dynamical system on a signed graph, which can be interpreted as a mathematical model of social networks in which the links can have both positive and negative connotations. In accordance with a concept from social…

Social and Information Networks · Computer Science 2015-06-16 Tyler H. Summers , Iman Shames

We study the target control problem of asynchronous Boolean networks, to identify a set of nodes, the perturbation of which can drive the dynamics of the network from any initial state to the desired steady state (or attractor). We are…

Systems and Control · Electrical Eng. & Systems 2020-06-04 Cui Su , Jun Pang

Active biological flow networks pervade nature and span a wide range of scales, from arterial blood vessels and bronchial mucus transport in humans to bacterial flow through porous media or plasmodial shuttle streaming in slime molds.…

Biological Physics · Physics 2016-07-28 Francis G. Woodhouse , Aden Forrow , Joanna B. Fawcett , Jörn Dunkel

Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions (from molecules in gene regulatory…

Molecular Networks · Quantitative Biology 2023-10-20 Jordan C. Rozum , Colin Campbell , Eli Newby , Fatemeh Sadat Fatemi Nasrollahi , Reka Albert

We consider a linear transport equation on the edges of a network with time-varying coefficients. Using methods for non-autonomous abstract Cauchy problems, we obtain well-posedness of the problem and describe the asymptotic profile of the…

Analysis of PDEs · Mathematics 2014-03-12 Fatih Bayazit , Britta Dorn , Marjeta Kramar Fijavž

Random walks represent an important tool for probing the structural and dynamical properties of networks and modeling transport and diffusion processes on networks. However, when individuals' movement becomes dictated by more complicated…

Pattern Formation and Solitons · Physics 2022-11-24 Per Sebastian Skardal
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