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We perform a numerical approximation of coherent sets in finite-dimensional smooth dynamical systems by computing singular vectors of the transfer operator for a stochastically perturbed flow. This operator is obtained by solution of a…

Dynamical Systems · Mathematics 2016-10-17 Andreas Denner , Oliver Junge , Daniel Matthes

In this work, we are concerned with the Fokker-Planck equations associated with the Nonlinear Noisy Leaky Integrate-and-Fire model for neuron networks. Due to the jump mechanism at the microscopic level, such Fokker-Planck equations are…

Numerical Analysis · Mathematics 2020-10-12 Jingwei Hu , Jian-Guo Liu , Yantong Xie , Zhennan Zhou

Despite the huge number of neurons composing a brain network, ongoing activity of local cell assemblies composing cortical columns is intrinsically stochastic. Fluctuations in their instantaneous rate of spike firing $\nu(t)$ scale with the…

Neurons and Cognition · Quantitative Biology 2024-04-15 Gianni V. Vinci , Roberto Benzi , Maurizio Mattia

Populations of spiking neuron models have densities of their microscopic variables (e.g., single-cell membrane potentials) whose evolution fully capture the collective dynamics of biological networks, even outside equilibrium. Despite its…

Neurons and Cognition · Quantitative Biology 2021-11-08 Gianni V. Vinci , Maurizio Mattia

The effect of a temporally correlated afferent current on the firing rate of a leaky integrate-and-fire (LIF) neuron is studied. This current is characterized in terms of rates, auto and cross-correlations, and correlation time scale…

Disordered Systems and Neural Networks · Physics 2009-11-07 R. Moreno , J. de la Rocha , A. Renart , N. Parga

The Fokker--Planck equation is a key ingredient of many models in physics, and related subjects, and arises in a diverse array of settings. Analytical solutions are limited to special cases, and resorting to numerical simulation is often…

Mathematical Physics · Physics 2019-02-20 R. J. Martin , R. V. Craster , A. Pannier , M. J. Kearney

Accurate prediction of rarefied gas flows is important for space vehicle design, particularly in rarefied regimes where the Navier-Stokes equations are no more valid. While the direct simulation Monte Carlo (DSMC) method acts as a numerical…

Fluid Dynamics · Physics 2025-07-01 Joonbeom Kim , Eunji Jun

We propose an upwind finite volume method for a system of two kinetic equations in one dimension that are coupled through nonlocal interaction terms. These cross-interaction systems were recently obtained as the mean-field limit of a…

Numerical Analysis · Mathematics 2023-09-15 Julia I. M. Hauser , Valeria Iorio , Markus Schmidtchen

The response of a noisy integrate-and-fire neuron with reset to periodic input is investigated. We numerically obtain the first-passage-time density of the pertaining Ornstein-Uhlenbeck process and show how the power spectral density of the…

Biological Physics · Physics 2009-10-30 Hans E. Plesser , Shigeru Tanaka

One of the most important challenges in mathematical neuroscience is to properly illustrate the stochastic nature of neurons. Among different approaches, the noisy leaky integrate-and-fire and the escape rate models are probably the most…

Analysis of PDEs · Mathematics 2017-02-07 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

In this work, we are concerned with a Fokker-Planck equation related to the nonlinear noisy leaky integrate-and-fire model for biological neural networks which are structured by the synaptic weights and equipped with the Hebbian learning…

Numerical Analysis · Mathematics 2022-06-28 Qing He , Jingwei Hu , Zhennan Zhou

Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…

Neurons and Cognition · Quantitative Biology 2009-06-12 Eugenio Urdapilleta , Ines Samengo

In the development of multiscale biological models it is crucial to establish a connection between discrete microscopic or mesoscopic stochastic models and macroscopic continuous descriptions based on cellular density. In this paper a…

Biological Physics · Physics 2009-11-13 Mark Alber , Nan Chen , Pavel M. Lushnikov , Stuart A. Newman

We introduce a model of long-range interacting particles evolving under a stochastic Monte Carlo dynamics, in which possible increase or decrease in the values of the dynamical variables is accepted with preassigned probabilities. For…

Statistical Mechanics · Physics 2013-12-03 Shamik Gupta , Thierry Dauxois , Stefano Ruffo

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

We study a system of perfect integrate-and-fire inhibitory neurons. It is a system of stochastic processes which interact through receiving an instantaneous increase at the moments they reach certain thresholds. In the absence of…

Probability · Mathematics 2018-09-25 Timofei Prasolov

The method of choice for integrating the time-dependent Fokker-Planck equation in high-dimension is to generate samples from the solution via integration of the associated stochastic differential equation. Here, we study an alternative…

Machine Learning · Computer Science 2023-02-17 Nicholas M. Boffi , Eric Vanden-Eijnden

Time-resolved single-cell omics data offers high-throughput, genome-wide measurements of cellular states, which are instrumental to reverse-engineer the processes underpinning cell fate. Such technologies are inherently destructive,…

Machine Learning · Computer Science 2026-02-04 Stephen Zhang , Suryanarayana Maddu , Xiaojie Qiu , Victor Chardès

Interspike intervals describe the output of neurons. Signal transmission in a neuronal network implies that the output of some neurons becomes the input of others. The output should reproduce the main features of the input to avoid a…

Probability · Mathematics 2022-09-29 Petr Lansky , Federico Polito , Laura Sacerdote

We consider a leaky integrate-and-fire neuron with deterministic subthreshold dynamics and a firing threshold that evolves as an Ornstein-Uhlenbeck process. The formulation of this minimal model is motivated by the experimentally observed…

Neurons and Cognition · Quantitative Biology 2015-05-12 Wilhelm Braun , Paul C. Matthews , Rüdiger Thul