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This paper presents an innovative extension of spatial autoregressive (SAR) models, introducing spatial coefficients specific to each spatial region that evolve over time. The proposed estimation methodology covers both homoscedastic and…

Methodology · Statistics 2025-02-24 N. A. Cruz , D. A. Romero , O. O. Melo

The classical multilevel model fails to capture the proximity effect in epidemiological studies, where subjects are nested within geographical units. Multilevel Conditional Autoregressive models are alternatives to help explain the spatial…

Methodology · Statistics 2021-11-24 Dany Djeudeu , Susanne Moebus , Katja Ickstadt

Spatial confounding is a common issue in spatial regression models, occurring when spatially varying covariates correlate with the spatial effect included in the model. This dependence, particularly at high spatial frequencies, can…

Methodology · Statistics 2025-12-16 Isa Marques , Paul F. V. Wiemann

Spatial variable genes (SVGs) reveal critical information about tissue architecture, cellular interactions, and disease microenvironments. As spatial transcriptomics (ST) technologies proliferate, accurately identifying SVGs across diverse…

Applications · Statistics 2025-10-21 Jiawen Chen , Jinwei Zhang , Dongshen Peng , Yutong Song , Aitong Ruan , Yun Li , Didong Li

Makeup transfer is a process of transferring the makeup style from a reference image to the source images, while preserving the source images' identities. This technique is highly desirable and finds many applications. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Xiaojing Zhong , Xinyi Huang , Zhonghua Wu , Guosheng Lin , Qingyao Wu

Aberrantly regulated cell motility is a hallmark of cancer cells. A hybrid agent-based model has been developed to investigate the synergistic and antagonistic cell motility-impacting effects of three microenvironment variables…

Cell Behavior · Quantitative Biology 2008-06-26 L. Leon Chen , Le Zhang , Jeongah Yoon , Thomas S. Deisboeck

Although spatial models for areal data are widely used in multilevel settings, the conditions under which spatial and nonspatial random effects yield equivalent posterior inference for regression coefficients have never been formally…

Methodology · Statistics 2026-05-12 Shuqi Lin , Joshua L. Warren

In this paper we propose a new approach for tomographic reconstruction with spatially varying regularization parameter. Our work is based on the SA-TV image restoration model proposed in [3] where an automated parameter selection rule for…

Numerical Analysis · Mathematics 2018-11-27 Yiqiu Dong , Carola-Bibiane Schönlieb

Cancer survival prediction is important for developing personalized treatments and inducing disease-causing mechanisms. Multi-omics data integration is attracting widespread interest in cancer research for providing information for…

Genomics · Quantitative Biology 2022-07-12 Xing Wu , Qiulian Fang

Estimating associations between spatial covariates and responses - rather than merely predicting responses - is central to environmental science, epidemiology, and economics. For instance, public health officials might be interested in…

Machine Learning · Statistics 2025-11-11 David R. Burt , Renato Berlinghieri , Stephen Bates , Tamara Broderick

The goal of spatial-configuration-based classification is to build a classifier to distinguish two classes (e.g., responder, non-responder) based on the spatial arrangements (e.g., spatial interactions between different point categories)…

Computer Vision and Pattern Recognition · Computer Science 2022-03-21 Majid Farhadloo , Carl Molnar , Gaoxiang Luo , Yan Li , Shashi Shekhar , Rachel L. Maus , Svetomir N. Markovic , Raymond Moore , Alexey Leontovich

Large samples have been generated routinely from various sources. Classic statistical models, such as smoothing spline ANOVA models, are not well equipped to analyze such large samples due to expensive computational costs. In particular,…

Methodology · Statistics 2020-04-23 Xiaoxiao Sun , Wenxuan Zhong , Ping Ma

Species distribution models (SDMs) are increasingly applied across macroscales. Such models typically assume that a single set of regression coefficients can adequately describe species-environment relationships and/or population trends.…

Multivariate regression models and ANOVA are probably the most frequently applied methods of all statistical analyses. We study the case where the predictors are qualitative variables, and the response variable is quantitative. In this…

Applications · Statistics 2021-05-04 Abraham Gutierrez , Sebastian Müller

High-dimensional variable selection, with many more covariates than observations, is widely documented in standard regression models, but there are still few tools to address it in non-linear mixed-effects models where data are collected…

Statistics Theory · Mathematics 2024-04-08 Marion Naveau , Guillaume Kon Kam King , Renaud Rincent , Laure Sansonnet , Maud Delattre

Neural network ensembles, such as Bayesian neural networks (BNNs), have shown success in the areas of uncertainty estimation and robustness. However, a crucial challenge prohibits their use in practice. BNNs require a large number of…

Machine Learning · Computer Science 2022-07-15 Namuk Park , Songkuk Kim

Hierarchical spatial models are very flexible and popular for a vast array of applications in areas such as ecology, social science, public health, and atmospheric science. It is common to carry out Bayesian inference for these models via…

Computation · Statistics 2021-05-17 Ben Seiyon Lee , Murali Haran

Studies in environmental and epidemiological sciences are often spatially varying and observational in nature with the aim of establishing cause and effect relationships. One of the major challenges with such studies is the presence of…

Methodology · Statistics 2023-05-16 Sayli Pokal , Yawen Guan , Honglang Wang , Yuzhen Zhou

We propose a new method for model selection and model fitting in multivariate nonparametric regression models, in the framework of smoothing spline ANOVA. The ``COSSO'' is a method of regularization with the penalty functional being the sum…

Statistics Theory · Mathematics 2007-06-13 Yi Lin , Hao Helen Zhang

In medical diagnostics, leveraging multiple biomarkers can significantly improve classification accuracy compared to using a single biomarker. While existing methods based on exponential tilting or density ratio models have shown promise,…

Methodology · Statistics 2026-01-08 Fangyong Zheng , Pengfei Li , Tao Yu
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