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Intercellular exchange networks are essential for the adaptive capabilities of populations of cells. While diffusional exchanges have traditionally been difficult to map, recent advances in nanotechnology enable precise probing of exchange…

Statistical Mechanics · Physics 2024-12-13 Luís C. F. Latoski , Andrea De Martino , Daniele De Martino

Stochastic kinetic models describe systems across biology, chemistry, and physics where discrete events and small populations render deterministic approximations inadequate. Parameter inference and inverse design in these systems require…

Computational Physics · Physics 2026-03-06 Francesco Mottes , Qian-Ze Zhu , Michael P. Brenner

We consider stability analysis of constrained switching linear systems in which the dynamics is unknown and whose switching signal is constrained by an automaton. We propose a data-driven Lyapunov framework for providing probabilistic…

Systems and Control · Electrical Eng. & Systems 2022-07-15 Adrien Banse , Zheming Wang , Raphaël M. Jungers

We consider multiple-period states in systems of periodically modulated qubits. In such states the discrete time-translation symmetry imposed by the modulation is broken. We explicitly show how multiple-period states emerge in the simplest…

Quantum Physics · Physics 2019-10-03 M. I. Dykman

We define the syntax and reduction relation of a recursively typed lambda calculus with a parallel case-function (a parallel conditional). The reduction is shown to be confluent. We interpret the recursive types as information systems in a…

Logic in Computer Science · Computer Science 2008-06-12 Fritz Müller

We study the stochastic dynamics of a system of interacting species in a stochastic environment by means of a continuous-time Markov chain with transition rates depending on the state of the environment. Models of gene regulation in systems…

Dynamical Systems · Mathematics 2019-12-03 Daniele Cappelletti , Abhishek Pal Majumder , Carsten Wiuf

Coupling an isolated emitter to a single mode of the electromagnetic field is now routinely achieved and well understood. Current efforts aim to explore the coherent dynamics of emitters coupled to several electromagnetic modes (EM).…

We address the challenge of crosstalk in quantum multiplexing -an obstacle to scaling throughput in quantum communication networks. Crosstalk arises when physically coupled quantum modes interfere, degrading signal fidelity. We propose a…

Quantum Physics · Physics 2025-06-30 Seid Koudia , Symeon Chatzinotas

Answering complex questions that require making latent decisions is a challenging task, especially when limited supervision is available. Recent works leverage the capabilities of large language models (LMs) to perform complex question…

Computation and Language · Computer Science 2022-12-09 Dheeru Dua , Shivanshu Gupta , Sameer Singh , Matt Gardner

Structure-based coarse graining of molecular systems offers a systematic route to reproduce the many-body potential of mean force. Unfortunately, common strategies are inherently limited by the molecular mechanics force field employed.…

Soft Condensed Matter · Physics 2018-12-27 Tristan Bereau , Joseph F. Rudzinski

Molecular Dynamics (MD) simulations are fundamental computational tools for the study of proteins and their free energy landscapes. However, sampling protein conformational changes through MD simulations is challenging due to the relatively…

Biomolecules · Quantitative Biology 2023-07-20 Diego E. Kleiman , Hassan Nadeem , Diwakar Shukla

Stochastic models of biochemical reaction networks are widely used to capture intrinsic noise in cellular systems. The typical formulation of these models are based on Markov processes for which there is extensive research on efficient…

Molecular Networks · Quantitative Biology 2025-12-03 Thomas P. Steele , David J. Warne

Existing approaches to analogue quantum simulations of time-dependent quantum systems rely on perturbative corrections to quantum simulations of time-independent quantum systems. We overcome this restriction to perturbative treatments with…

Quantum Physics · Physics 2024-02-13 Boyuan Shi , Florian Mintert

Multiple phenotypic states often arise in a single cell with different gene-expression states that undergo transcription regulation with positive feedback. Recent experiments have shown that at least in E. coli, the gene state switching can…

Molecular Networks · Quantitative Biology 2015-10-28 Hao Ge , Hong Qian , Sunney Xiaoliang Xie

In many real-world problems, recovering sparse signals from underdetermined linear systems remains a fundamental challenge. Although $\ell_1$ norm minimization is widely used, it suffers from estimation bias that prevents it from reaching…

Information Theory · Computer Science 2026-04-16 Keisuke Morita , Federico Ricci-Tersenghi , Masayuki Ohzeki

Evolutionary symbolic regression approaches are powerful tools that can approximate an explicit mapping between input features and observation for various problems. However, ensuring that explored expressions maintain consistency with…

Optimization and Control · Mathematics 2024-11-19 Maximilian Reissmann , Yuan Fang , Andrew Ooi , Richard Sandberg

We consider a combinatorial problem occurring naturally in a group theoretical setting and provide a constructive solution in a special case. More precisely, in 1999 the author established a logarithmic bound for the derived length of the…

Combinatorics · Mathematics 2014-07-18 Thomas Michael Keller

This work develops a rigorous framework for analysing ergodicity and mixing in time-inhomogeneous quantum dynamics. It considers quantum evolutions generated by sequences of quantum channels and examines in detail the relationship between…

Mathematical Physics · Physics 2026-03-25 Abdessatar Souissi

We discuss the transition paths in a coupled bistable system consisting of interacting multiple identical bistable motifs. We propose a simple model of coupled bistable gene circuits as an example, and show that its transition paths are…

Molecular Networks · Quantitative Biology 2016-11-03 Chengzhe Tian , Namiko Mitarai

For a model nonlinear dynamical system, we show how one may obtain its bifurcation behavior by introducing noise into the dynamics and then studying the resulting Langevin dynamics in the weak-noise limit. A suitable quantity to capture the…

Adaptation and Self-Organizing Systems · Physics 2019-02-06 Debraj Das , Sayan Roy , Shamik Gupta