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Examining individual components of cellular systems has been successful in uncovering molecular reactions and interactions. However, the challenge lies in integrating these components into a comprehensive system-scale map. This difficulty…

Other Quantitative Biology · Quantitative Biology 2024-07-03 Nima Dehghani

The DICE workshop explores the area of Implicit Computational Complexity (ICC), which grew out from several proposals to use logic and formal methods to provide languages for complexity-bounded computation (e.g. Ptime, Logspace…

Logic in Computer Science · Computer Science 2017-04-19 Guillaume Bonfante , Georg Moser

The 21st century society relies on computing systems more than ever. Computers are no longer simply machines that are used by organizations or at home. They are embedded everywhere, from cell phones to cars or industrial control devices,…

Software Engineering · Computer Science 2014-05-16 Alexander Romanovsky , Marc-Olivier Killijian

Living systems, particularly multicellular systems, often seem hopelessly complex. But recent studies have suggested that beneath this complexity, there may be unifying quantitative principles that we are only now starting to unravel. All…

Molecular Networks · Quantitative Biology 2016-03-01 Eduardo P. Olimpio , Diego R. Gomez-Alvarez , Hyun Youk

Clustering of ligand-binding receptors of different types on thickened isles of the cell membrane, namely lipid rafts, is an experimentally observed phenomenon. Although its influence on cell response is deeply investigated, the role of the…

Biological Physics · Physics 2020-06-01 A. R. Carotenuto , L. Lunghi , V. Piccolo , M. Babaei , K. Dayal , N. M. Pugno , M. Zingales , L. Deseri , M. Fraldi

The special theme of DCM 2009, co-located with ICALP 2009, concerned Computational Models From Nature, with a particular emphasis on computational models derived from physics and biology. The intention was to bring together different…

Computational Engineering, Finance, and Science · Computer Science 2009-11-17 S. Barry Cooper , Vincent Danos

Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…

Other Quantitative Biology · Quantitative Biology 2024-04-17 Daniel Koch , Akhilesh Nandan , Gayathri Ramesan , Aneta Koseska

Artificial neural networks and computational neuroscience models have made tremendous progress, allowing computers to achieve impressive results in artificial intelligence (AI) applications, such as image recognition, natural language…

Neural and Evolutionary Computing · Computer Science 2019-11-05 Giacomo Indiveri , Yulia Sandamirskaya

Process algebra provides abstract and rigorous means for studying communicating concurrent systems. Coordination languages also provide abstract means for the specifying and programming communication of components. Hence, the two fields…

Logic in Computer Science · Computer Science 2011-08-09 Luca Aceto , Mohammad Reza Mousavi

Replication time is among the most important components of a bacterial cell's reproductive fitness. Paradoxically, larger cells replicate in less time than smaller cells despite the fact that building a larger cell requires increased…

Neural and Evolutionary Computing · Computer Science 2021-03-16 Lance R. Williams

The increasing interest in understanding the behavior of the biological neural networks, and the increasing utilization of artificial neural networks in different fields and scales, both require a thorough understanding of how neuromorphic…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-12 János Végh , Ádám J. Berki

Membrane organization is essential for cellular functions such as signal transduction and membrane trafficking. A major challenge is to understand the lateral heterogeneous structures in membranes and membrane fluidity in the presence of…

Soft Condensed Matter · Physics 2007-11-09 Chun-Lai Ren , Yu-qiang Ma

Quantitative aspects of computation are important and sometimes essential in characterising the behavior and determining the properties of systems. They are related to the use of physical quantities (storage space, time, bandwidth, etc.) as…

Logic in Computer Science · Computer Science 2013-08-15 Luca Bortolussi , Herbert Wiklicky

In this article we highlight chemotaxis (cellular movement) as a rich source of potential engineering applications and computational models, highlighting current research and possible future work. We first give a brief description of the…

Cell Behavior · Quantitative Biology 2007-05-23 Martyn Amos , David A. Hodgson , Alan Gibbons

Nanophotonic devices excel at confining light into intense hot spots of the electromagnetic near fields, creating unprecedented opportunities for light-matter coupling and surface-enhanced sensing. Recently, all-dielectric metasurfaces with…

We review the key role played by mathematical modelling in elucidating two centre-finding patterning systems in E. coli: midcell division positioning by the MinCDE system and DNA partitioning by the ParABS system. We focus particularly on…

Subcellular Processes · Quantitative Biology 2019-01-21 Sean M. Murray , Martin Howard

Modeling electronic systems is an important application for quantum computers. In the context of materials science, an important open problem is the computational description of chemical reactions on surfaces. In this work, we outline a…

A number of biological processes, such as embryo development, cancer metastasis or wound healing, rely on cells moving in concert. The mechanisms leading to the emergence of coordinated motion remain however largely unexplored. Although…

Cell Behavior · Quantitative Biology 2011-08-23 Alexandre J Kabla

Many cellular processes involve information processing and decision making. We can probe these processes at increasing molecular detail. The analysis of heterogeneous data remains a challenge that requires new ways of thinking about cells…

Cell Behavior · Quantitative Biology 2024-12-03 Lucy Ham , Taylor E. Woodford , Megan A. Coomer , Michael P. H. Stumpf

Living organisms rely on endogenous feedback mechanisms to maintain homeostasis in the presence of uncertainty and environmental fluctuations. An emerging challenge at the interface of control systems engineering and synthetic biology is…

Systems and Control · Electrical Eng. & Systems 2026-02-24 Mario di Bernardo