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The complexity of biological systems and processes, spanning molecular to macroscopic scales, necessitates the use of multiscale simulations to get a comprehensive understanding. Quantum mechanics/molecular mechanics (QM/MM) molecular…

Computational models are invaluable in capturing the complexities of real-world biological processes. Yet, the selection of appropriate algorithms for inference tasks, especially when dealing with real-world observational data, remains a…

Applications · Statistics 2024-10-01 Xiaoyu Wang , Ryan P. Kelly , Adrianne L. Jenner , David J. Warne , Christopher Drovandi

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

Within the diverse interdisciplinary life sciences domains, semantic, workflow, and methodological ambiguities can prevent the appreciation of explanations of phenomena, handicap the use of computational models, and hamper communication…

Quantitative Methods · Quantitative Biology 2018-01-16 C. Anthony Hunt , Ahmet Erdemir , Feilim Mac Gabhann , William W. Lytton , Edward A. Sander , Mark K. Transtrum , Lealem Mulugeta

It is now five years since the launch of the International Journal of Bio-Inspired Computation (IJBIC). At the same time, significant new progress has been made in the area of bio-inspired computation. This review paper summarizes the…

Optimization and Control · Mathematics 2014-04-01 Xin-She Yang , Zhihua Cui

The importance of molecular-scale forces in sculpting biological form and function has been acknowledged for more than a century. Accounting for forces in biology is a problem that lies at the intersection of soft condensed matter physics,…

Soft Condensed Matter · Physics 2025-12-10 K. Vijay Kumar , Mandar M. Inamdar , Pramod A. Pullarkat , Gautam I. Menon

Programmable biomolecule-mediated computing is a new computing paradigm as compared to contemporary electronic computing. It employs nucleic acids and analogous biomolecular structures as information-storing and -processing substrates to…

Emerging Technologies · Computer Science 2024-01-30 Jian-Jun Shu , Zi Hian Tan , Qi-Wen Wang , Kian-Yan Yong

Cellular bioelectricity describes the biological phenomenon in which cells in living tissue generate and maintain patterns of voltage gradients induced by differing concentrations of charged ions. A growing body of research suggests that…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-27 Seth Gilbert , James Maguire , Calvin Newport

Biological sequence comparison is a key step in inferring the relatedness of various organisms and the functional similarity of their components. Thanks to the Next Generation Sequencing efforts, an abundance of sequence data is now…

Machine Learning · Computer Science 2016-09-13 Dhananjay Kimothi , Akshay Soni , Pravesh Biyani , James M. Hogan

Modern hardware platforms, from the very small to the very large, increasingly provide parallel and distributed computing resources for applications to maximise performance. Many applications therefore need to make effective use of tens,…

Programming Languages · Computer Science 2019-04-02 Francisco Martins , Dominic Orchard

The activity of biological cells is primarily based on chemical reactions and typically modeled as a reaction-diffusion system. Cells are, however, highly crowded with macromolecules, including a variety of molecular machines such as…

Biological Physics · Physics 2018-11-02 Yuichi Togashi

Classical Logic and Computation (CL&C) 2014 is the fifth edition of this workshop series. The workshop series intends to cover all work aiming to explore computational aspects of classical logic and mathematics. Its focus is on the…

Logic in Computer Science · Computer Science 2014-09-10 Paulo Oliva

Quantum Biology is emerging as a new field at the intersection between fundamental physics and biology, promising novel insights into the nature and origin of biological order. We discuss several elements of QBCL (Quantum Biology at…

Other Quantitative Biology · Quantitative Biology 2013-04-04 Michael Bordonaro , Vasily Ogryzko

The evolution of complexity has been a central theme for Biology and Artificial Life (Bonner, 1988; Bedau et al., 2000). Complexification has been interpreted in different ways: as a process of diversification between evolving units…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Carlos Gershenson , Tom Lenaerts

In silico, cell based approaches for modeling biological morphogenesis are used to test and validate our understanding of the biological and mechanical process that are at work during the growth and the organization of multi-cell tissues.…

Biological Physics · Physics 2026-01-06 Raphaël Conradin , Christophe Coreixas , Jonas Latt , Bastien Chopard

Biomembranes play a central role in various phenomena like locomotion of cells, cell-cell interactions, packaging of nutrients, and in maintaining organelle morphology and functionality. During these processes, the membranes undergo…

Quantitative Methods · Quantitative Biology 2021-12-01 Debabrata Auddya , Xiaoxuan Zhang , Rahul Gulati , Ritvik Vasan , Krishna Garikipati , Padmini Rangamani , Shiva Rudraraju

Molecular biology and biochemistry interpret microscopic processes in the living world in terms of molecular structures and their interactions, which are quantum mechanical by their very nature. Whereas the theoretical foundations of these…

Quantum Physics · Physics 2023-07-07 Alberto Baiardi , Matthias Christandl , Markus Reiher

Biomechanics is a scientific discipline that studies the forces acting on a body and the effects they produce. In this paper, we bring together biomechanists and networking researchers to shed light into how research efforts in…

Networking and Internet Architecture · Computer Science 2021-03-30 Spyridon Mastorakis , Andreas Skiadopoulos , Susmit Shannigrahi , Aaron Likens , Boubakr Nour , Nicholas Stergiou

This study presents a theoretical model for a self-replicating mechanical system inspired by biological processes within living cells and supported by computer simulations. The model decomposes self-replication into core components, each of…

Other Quantitative Biology · Quantitative Biology 2025-02-18 Ralph P. Lano
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