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Networks are ubiquitous structure that describes complex relationships between different entities in the real world. As a critical component of prediction task over nodes in networks, learning the feature representation of nodes has become…

Machine Learning · Computer Science 2018-09-10 Hansheng Xue , Jiajie Peng , Xuequn Shang

Deep Operator Network (DeepONet), a recently introduced deep learning operator network, approximates linear and nonlinear solution operators by taking parametric functions (infinite-dimensional objects) as inputs and mapping them to…

Computational Engineering, Finance, and Science · Computer Science 2023-10-12 Junyan He , Shashank Kushwaha , Jaewan Park , Seid Koric , Diab Abueidda , Iwona Jasiuk

Recently, dynamic inference has emerged as a promising way to reduce the computational cost of deep convolutional neural network (CNN). In contrast to static methods (e.g. weight pruning), dynamic inference adaptively adjusts the inference…

Computer Vision and Pattern Recognition · Computer Science 2019-12-18 Zhihang Yuan , Bingzhe Wu , Zheng Liang , Shiwan Zhao , Weichen Bi , Guangyu Sun

Prediction of one-dimensional protein structures such as secondary structures and contact numbers is useful for the three-dimensional structure prediction and important for the understanding of sequence-structure relationship. Here we…

Biomolecules · Quantitative Biology 2007-05-23 Akira R. Kinjo , Ken Nishikawa

Prior results for tRNA and 5S rRNA demonstrated that secondary structure prediction accuracy can be significantly improved by modifying the parameters in the multibranch loop entropic penalty function. However, for reasons not well…

Biomolecules · Quantitative Biology 2025-03-28 Svetlana Poznanović , Owen Cardwell , Christine Heitsch

Sparse neural networks are important for achieving better generalization and enhancing computation efficiency. This paper proposes a novel learning approach to obtain sparse fully connected layers in neural networks (NNs) automatically. We…

Machine Learning · Computer Science 2021-04-28 Mengqiao Han , Xiabi Liu , Zhaoyang Hai , Zhengwen Li

True-time-delay (TTD) beamformers can produce wideband, squint-free beams in both analog and digital signal domains, unlike frequency-dependent FFT beams. Our previous work showed that TTD beamformers can be efficiently realized using the…

Machine Learning · Computer Science 2025-03-27 Hansaka Aluvihare , Sivakumar Sivasankar , Xianqi Li , Arjuna Madanayake , Sirani M. Perera

Trusted Execution Environments (TEEs) have become a promising solution to secure DNN models on edge devices. However, the existing solutions either provide inadequate protection or introduce large performance overhead. Taking both security…

Cryptography and Security · Computer Science 2024-05-08 Ziyu Liu , Tong Zhou , Yukui Luo , Xiaolin Xu

Dimensionality reduction and manifold learning methods such as t-Distributed Stochastic Neighbor Embedding (t-SNE) are routinely used to map high-dimensional data into a 2-dimensional space to visualize and explore the data. However, two…

Machine Learning · Computer Science 2019-05-27 Bo Kang , Darío García García , Jefrey Lijffijt , Raúl Santos-Rodríguez , Tijl De Bie

Consider the network of all secondary structures of a given RNA sequence, where nodes are connected when the corresponding structures have base pair distance one. The expected degree of the network is the average number of neighbors, where…

Biomolecules · Quantitative Biology 2014-11-04 Peter Clote

In this paper, we propose a novel Explanation Neural Network (XNN) to explain the predictions made by a deep network. The XNN works by learning a nonlinear embedding of a high-dimensional activation vector of a deep network layer into a…

Computer Vision and Pattern Recognition · Computer Science 2020-12-14 Zhongang Qi , Saeed Khorram , Fuxin Li

In this paper we enumerate $k$-noncrossing RNA pseudoknot structures with given minimum arc- and stack-length. That is, we study the numbers of RNA pseudoknot structures with arc-length $\ge 3$, stack-length $\ge \sigma$ and in which there…

Biomolecules · Quantitative Biology 2007-12-04 Emma Y. Jin , Christian M. Reidys

This paper introduces a novel type of memetic algorithm based Topology and Weight Evolving Artificial Neural Network (TWEANN) system called DX Neural Network (DXNN). DXNN implements a number of interesting features, amongst which is: a…

Neural and Evolutionary Computing · Computer Science 2011-07-19 Gene I. Sher

Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in thus needed to understand the cell's working mechanism, and…

Quantitative Methods · Quantitative Biology 2011-02-21 Fantine Mordelet , Jean-Philippe Vert

Models for RNA secondary structures (the topology of folded RNA) without pseudo knots are disordered systems with a complex state-space below a critical temperature. Hence, a complex dynamical (glassy) behavior can be expected, when…

Disordered Systems and Neural Networks · Physics 2008-02-02 S. Wolfsheimer , B. Burghardt , A. Mann , A. K. Hartmann

The problem of RNA secondary structure design (also called inverse folding) is the following: given a target secondary structure, one aims to create a sequence that folds into, or is compatible with, a given structure. In several practical…

Quantitative Methods · Quantitative Biology 2013-08-02 Yu Zhou , Yann Ponty , Stéphane Vialette , Jérôme Waldispühl , Yi Zhang , Alain Denise

Convolutional architectures have recently been shown to be competitive on many sequence modelling tasks when compared to the de-facto standard of recurrent neural networks (RNNs), while providing computational and modeling advantages due to…

Machine Learning · Computer Science 2019-02-19 Emre Aksan , Otmar Hilliges

We propose Trusted Neural Network (TNN) models, which are deep neural network models that satisfy safety constraints critical to the application domain. We investigate different mechanisms for incorporating rule-based knowledge in the form…

Machine Learning · Computer Science 2018-05-21 Shalini Ghosh , Amaury Mercier , Dheeraj Pichapati , Susmit Jha , Vinod Yegneswaran , Patrick Lincoln

We propose three novel pruning techniques to improve the cost and results of inference-aware Differentiable Neural Architecture Search (DNAS). First, we introduce Prunode, a stochastic bi-path building block for DNAS, which can search over…

Machine Learning · Computer Science 2023-01-06 Sławomir Kierat , Mateusz Sieniawski , Denys Fridman , Chen-Han Yu , Szymon Migacz , Paweł Morkisz , Alex-Fit Florea

RNA design is the search for a sequence or set of sequences that will fold into predefined structures, also known as the inverse problem of RNA folding. While numerous RNA design methods have been invented to find sequences capable of…

Biomolecules · Quantitative Biology 2024-08-13 Tianshuo Zhou , Wei Yu Tang , David H. Mathews , Liang Huang