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A modified fluctuation-dissipation-theorem (MFDT) for a non-equilibrium steady state (NESS) is experimentally checked by studying the position fluctuations of a colloidal particle whose motion is confined in a toroidal optical trap. The…

Task-free connectivity analyses have emerged as a powerful tool in functional neuroimaging. Because the cross-correlations that underlie connectivity measures are sensitive to distortion of time-series, here we used a novel dynamic phantom…

Neurons and Cognition · Quantitative Biology 2020-02-05 D. J. DeDora , S. Nedic , P. Katti , S. Arnab , L. L. Wald , A. Takahashi , K. R. A. Van Dijk , H. H. Strey , L. R. Mujica-Parodi

Time series measured from real-world systems are generally noisy, complex and display statistical properties that evolve continuously over time. Here, we present a method that combines wavelet analysis and non-stationary surrogates to…

Data Analysis, Statistics and Probability · Physics 2018-04-12 Mario Chavez , Bernard Cazelles

Amorphous dielectric materials have been known to host two-level systems (TLSs) for more than four decades. Recent developments on superconducting resonators and qubits enable detailed studies on the physics of TLSs. In particular,…

Quantum Physics · Physics 2021-09-23 J. H. Béjanin , C. T. Earnest , A. S. Sharafeldin , M. Mariantoni

The transition of the power grid requires new technologies and methodologies, which can only be developed and tested in simulations. Especially larger simulation setups with many levels of detail can become quite slow. Therefore, the number…

Signal Processing · Electrical Eng. & Systems 2020-06-23 Stephan Balduin , Tom Westermann , Erika Puiutta

Surrogate models provide compact relations between user-defined input parameters and output quantities of interest, enabling the efficient evaluation of complex parametric systems in many-query settings. Such capabilities are essential in a…

Numerical Analysis · Mathematics 2026-03-16 Matteo Giacomini , Pedro Díez

The non-equilibrium dynamics of mesoscale phase transitions are fundamentally shaped by thermal fluctuations, which not only seed instabilities but actively control kinetic pathways, including rare barrier-crossing events such as nucleation…

Computational Physics · Physics 2026-04-14 Luning Sun , Van Hai Nguyen , Shusen Liu , John Klepeis , Fei Zhou

Biomolecules exhibit conformational fluctuations near equilibrium states, inducing uncertainty in various biological properties in a dynamic way. We have developed a general method to quantify the uncertainty of target properties induced by…

Biomolecules · Quantitative Biology 2018-10-02 Huan Lei , Xiu Yang , Bin Zheng , Guang Lin , Nathan A. Baker

Lempel-Ziv complexity (LZ) [1] and its variants have been used widely to identify non-random patterns in biomedical signals obtained across distinct physiological states. Non-random signatures of the complexity measure can occur under…

Chaotic Dynamics · Physics 2011-11-10 Radhakrishnan Nagarajan

The method of surrogate data is a tool to test whether data were generated by some class of model. Tests based on the periodogram have been proposed to decide if linear systems driven by Gaussian noise could have generated a sample time…

comp-gas · Physics 2008-02-03 J. Timmer

This article presents an original methodology for the prediction of steady turbulent aerodynamic fields. Due to the important computational cost of high-fidelity aerodynamic simulations, a surrogate model is employed to cope with the…

Fluid Dynamics · Physics 2019-12-05 Romain Dupuis , Jean-Christophe Jouhaud , Pierre Sagaut

Preterm infants are at high risk of developing brain injury in the first days of life as a consequence of poor cerebral oxygen delivery. Near-infrared spectroscopy (NIRS) is an established technology developed to monitor regional tissue…

Quantitative Methods · Quantitative Biology 2021-08-23 Minoo Ashoori , Eugene M. Dempsey , Fiona B. McDonald , John M. O'Toole

Stochastic majorization-minimization (SMM) is a class of stochastic optimization algorithms that proceed by sampling new data points and minimizing a recursive average of surrogate functions of an objective function. The surrogates are…

Optimization and Control · Mathematics 2023-03-22 Hanbaek Lyu

Machine learning surrogates are increasingly employed to replace expensive computational models for physics-based reliability analysis. However, their use introduces epistemic uncertainty from model approximation errors, which couples with…

Machine Learning · Computer Science 2025-09-24 Amirreza Tootchi , Xiaoping Du

Satellites and their instruments are subject to the motion stability throughout their lifetimes. The reliability of the large flexible space structures (LFSS) is particularly important for the motion stability of satellites and their…

Applications · Statistics 2022-04-20 Dongyu Zhao

Testing for nonlinearity is one of the most important preprocessing steps in nonlinear time series analysis. Typically, this is done by means of the linear surrogate data methods. But it is a known fact that the validity of the results…

Applications · Statistics 2011-02-01 Diego Guarin , Edilson Delgado , Alvaro Orozco

As researchers increasingly rely on machine learning models and LLMs to annotate unstructured data, such as texts or images, various approaches have been proposed to correct bias in downstream statistical analysis. However, existing methods…

Machine Learning · Computer Science 2025-12-29 Kentaro Nakamura

Advanced experimental measurements are crucial for driving theoretical developments and unveiling novel phenomena in condensed matter and material physics, which often suffer from the scarcity of facility resources and increasing…

Stochastic Petri Nets (SPNs) are an increasingly popular tool of choice for modeling discrete-event dynamics in areas such as epidemiology and systems biology, yet their parameter estimation remains challenging in general and in particular…

Machine Learning · Computer Science 2025-12-09 Bright Kwaku Manu , Trevor Reckell , Beckett Sterner , Petar Jevtic

Surrogate variables in electronic health records (EHR) and biobank data play an important role in biomedical studies due to the scarcity or absence of chart-reviewed gold standard labels. We develop a novel approach named SASH for {\bf…

Methodology · Statistics 2023-09-04 Yue Liu , Molei Liu , Zijian Guo , Tianxi Cai