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As a person learns a new skill, distinct synapses, brain regions, and circuits are engaged and change over time. In this paper, we develop methods to examine patterns of correlated activity across a large set of brain regions. Our goal is…

Neurons and Cognition · Quantitative Biology 2013-10-31 Danielle S. Bassett , Nicholas F. Wymbs , M. Puck Rombach , Mason A. Porter , Peter J. Mucha , Scott T. Grafton

Learning requires the traversal of inherently distinct cognitive states to produce behavioral adaptation. Yet, tools to explicitly measure these states with non-invasive imaging -- and to assess their dynamics during learning -- remain…

Coordinating multi-articulated bodies to generate purposeful movement is a formidable computational challenge. Yet the human motor system performs this task robustly in dynamic, uncertain environments, despite noisy and delayed feedback,…

Neurons and Cognition · Quantitative Biology 2026-02-24 Alessandro Salatiello

Modular structure is ubiquitous among real-world networks from related proteins to social groups. Here we analyze the modular organization of brain networks at a large-scale (voxel level) extracted from functional magnetic resonance imaging…

Data Analysis, Statistics and Probability · Physics 2009-04-16 M. Valencia , M. A. Pastor , MA. Fernandez-Seara , J. Artieda , J. Martinerie , M. Chavez

We study how modularity of the human brain changes as children develop into adults. Theory suggests that modularity can enhance the response function of a networked system subject to changing external stimuli. Thus, greater cognitive…

Neurons and Cognition · Quantitative Biology 2015-01-29 Man Chen , Michael W. Deem

The modular structure of brain networks supports specialized information processing, complex dynamics, and cost-efficient spatial embedding. Inter-individual variation in modular structure has been linked to differences in performance,…

Scaling model capacity has been vital in the success of deep learning. For a typical network, necessary compute resources and training time grow dramatically with model size. Conditional computation is a promising way to increase the number…

Machine Learning · Computer Science 2018-11-14 Louis Kirsch , Julius Kunze , David Barber

Humans excel at adapting perceptions and actions to diverse environments, enabling efficient interaction with the external world. This adaptive capability relies on the biological nervous system (BNS), which activates different brain…

Machine Learning · Computer Science 2024-11-12 Jingyao Wang , Huijie Guo , Wenwen Qiang , Jiangmeng Li , Changwen Zheng , Hui Xiong , Gang Hua

The brain modifies its synaptic strengths during learning in order to better adapt to its environment. However, the underlying plasticity rules that govern learning are unknown. Many proposals have been suggested, including Hebbian…

Neurons and Cognition · Quantitative Biology 2020-12-09 Aran Nayebi , Sanjana Srivastava , Surya Ganguli , Daniel L. K. Yamins

Behavioral changes in animals and humans, as a consequence of an error or a verbal instruction, can be extremely rapid. Improvement in behavioral performances are usually associated in machine learning and reinforcement learning to synaptic…

Neurons and Cognition · Quantitative Biology 2025-03-12 Cristiano Capone , Luca Falorsi

Continuous, adaptive learning, the ability to adapt to the environment and keep improving performance, is a hallmark of natural intelligence. Biological organisms excel in acquiring, transferring, and retaining knowledge while adapting to…

Neurons and Cognition · Quantitative Biology 2026-03-03 Jie Mei , Alejandro Rodriguez-Garcia , Daigo Takeuchi , Gabriel Wainstein , Nina Hubig , Yalda Mohsenzadeh , Srikanth Ramaswamy

Identifying and understanding modular organizations is centrally important in the study of complex systems. Several approaches to this problem have been advanced, many framed in information-theoretic terms. Our treatment starts from the…

Adaptation and Self-Organizing Systems · Physics 2015-01-19 Artemy Kolchinsky , Luis M. Rocha

Modularity has been widely studied as a mechanism to improve the capabilities of neural networks through various techniques such as hand-crafted modular architectures and automatic approaches. While these methods have sometimes shown…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Humphrey Munn , Marcus Gallagher

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Learning and decision making in the brain are key processes critical to survival, and yet are processes implemented by non-ideal biological building blocks which can impose significant error. We explore quantitatively how the brain might…

Neurons and Cognition · Quantitative Biology 2011-04-19 Jake Bouvrie , Jean-Jacques Slotine

Neural plasticity is an important functionality of human brain, in which number of neurons and synapses can shrink or expand in response to stimuli throughout the span of life. We model this dynamic learning process as an $L_0$-norm…

Neural and Evolutionary Computing · Computer Science 2021-05-04 Yang Li , Shihao Ji

Interconnected ensembles of biological entities are perhaps some of the most complex systems that modern science has encountered so far. In particular, scientists have concentrated on understanding how the complexity of the interacting…

Pattern Formation and Solitons · Physics 2020-11-18 Bram A. Siebert , Cameron L. Hall , James P. Gleeson , Malbor Asllani

This work examines the presence of modularity in pre-trained Transformers, a feature commonly found in human brains and thought to be vital for general intelligence. In analogy to human brains, we consider two main characteristics of…

Computation and Language · Computer Science 2023-10-31 Zhengyan Zhang , Zhiyuan Zeng , Yankai Lin , Chaojun Xiao , Xiaozhi Wang , Xu Han , Zhiyuan Liu , Ruobing Xie , Maosong Sun , Jie Zhou

Modular neural networks outperform nonmodular neural networks on tasks ranging from visual question answering to robotics. These performance improvements are thought to be due to modular networks' superior ability to model the compositional…

Machine Learning · Computer Science 2025-03-12 Akhilan Boopathy , Sunshine Jiang , William Yue , Jaedong Hwang , Abhiram Iyer , Ila Fiete

Flexible modulation of temporal dynamics in neural sequences underlies many cognitive processes. For instance, we can adaptively change the speed of motor sequences and speech. While such flexibility is influenced by various factors such as…

Neurons and Cognition · Quantitative Biology 2025-04-15 Tomoki Kurikawa , Kunihiko Kaneko