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Animals adjust their behavioral response to sensory input adaptively depending on past experiences. The flexible brain computation is crucial for survival and is of great interest in neuroscience. The nematode C. elegans modulates its…

Neurons and Cognition · Quantitative Biology 2024-02-26 Kevin S. Chen , Anuj K. Sharma , Jonathan W. Pillow , Andrew M. Leifer

Swimming microbes, such as bacteria and algae, live in diverse habitats including soil, ocean and human body which are characterized by structural boundaries and heterogeneous fluid flows. Although much progress has been made in…

Biological Physics · Physics 2022-02-16 Kejie Chen , Kairong Qin

Locomotion is typically studied either in continuous media where bodies and legs experience forces generated by the flowing medium, or on solid substrates dominated by friction. In the former, centralized coordination is believed to…

Biological Physics · Physics 2023-03-29 Baxi Chong , Juntao He , Shengkai Li , Eva Erickson , Kelimar Diaz , Tianyu Wang , Daniel Soto , Daniel I. Goldman

Bioconvection, a phenomenon arising from the collective motion of motile microorganisms, plays a crucial role in shaping microbial distributions, fluid dynamics, and bloom formation in aquatic environments. While extensive research has…

Biological Physics · Physics 2025-04-15 Samarendu Biswas , Sachidananda Mahato , Jayabrata Dhar

Locomotion by shape changes (spermatozoon swimming, snake slithering, bird flapping) or gas expulsion (rocket firing) is assumed to require environmental interaction, due to conservation of momentum. As first noted in (Wisdom, 2003) and…

Gastrulation, namely cell internalization, is a significant milestone during the development of metazoans from worm to human, which generates multiple embryonic layers with distinct cell fates and spatial organizations. Although many…

Cell Behavior · Quantitative Biology 2022-01-17 Jiao Miao , Guoye Guan , Chao Tang

A common feature of biological self-organization is how active agents communicate with each other or their environment via chemical signaling. Such communications, mediated by self-generated chemical gradients, have consequences for both…

Soft Condensed Matter · Physics 2023-11-07 Babak Vajdi Hokmabad , Suropriya Saha , Jaime Agudo-Canalejo , Ramin Golestanian , Corinna C. Maass

Living creatures exhibit a remarkable diversity of locomotion mechanisms, evolving structures specialised for interacting with their environment. In the vast majority of cases, locomotor behaviours such as flying, crawling, and running, are…

Biological Physics · Physics 2020-07-28 Kirsty Y. Wan

Cell motility in viscous fluids is ubiquitous and affects many biological processes, including reproduction, infection, and the marine life ecosystem. Here we review the biophysical and mechanical principles of locomotion at the small…

Soft Condensed Matter · Physics 2009-09-16 Eric Lauga , Thomas R. Powers

Motile cells often explore natural environments characterized by a high degree of structural complexity. Moreover cell motility is also intrinsically noisy due to spontaneous random reorientation and speed fluctuations. This interplay of…

Micro-swimmers such as bacteria perform random walks known as run-and-tumbles to move up chemo-attractant gradients and as a result aggregate with others. It is also known that such micro-swimmers can self-organize into macroscopic patterns…

Biological Physics · Physics 2016-08-31 Enkeleida Lushi

The biological fluids encountered by self-propelled cells display complex microstructures and rheology. We consider here the general problem of low-Reynolds number locomotion in a complex fluid. {Building on classical work on the transport…

Fluid Dynamics · Physics 2014-10-16 Eric Lauga

The design of amorphous entangled systems, specifically from soft and active materials, has the potential to open exciting new classes of active, shape-shifting, and task-capable 'smart' materials. However, the global emergent mechanics…

Soft Condensed Matter · Physics 2022-07-11 William Savoie , Harry Tuazon , M. Saad Bhamla , Daniel I. Goldman

Organisms that locomote by propagating waves of body bending can maintain performance across heterogeneous environments by modifying their gait frequency $\omega$ or wavenumber $k$. We identify a unifying relationship between these…

Biological Physics · Physics 2025-10-02 Christopher J. Pierce , Daniel Irvine , Lucinda Peng , Xuefei Lu , Hang Lu , Daniel I. Goldman

There is increasing evidence that mammalian cells not only crawl on substrates but can also swim in fluids. To elucidate the mechanisms of the onset of motility of cells in suspension, a model which couples actin and myosin kinetics to…

Biological Physics · Physics 2019-09-18 Alexander Farutin , Jocelyn Etienne , Chaouqi Misbah , Pierre Recho

The motility of microorganisms is influenced greatly by their hydrodynamic interactions with the fluidic environment they inhabit. We show by direct experimental observation of the bi-flagellated alga Chlamydomonas reinhardtii that fluid…

Biological Physics · Physics 2015-11-03 Boyang Qin , Arvind Gopinath , Jing Yang , Jerry P Gollub , Paulo E Arratia

The hydrodynamics of a flagellated microorganism is investigated when swimming close to a planar free-slip surface by means of numerical solu- tions of the Stokes equations obtained via a Boundary Element Method. Depending on the initial…

Fluid Dynamics · Physics 2017-03-31 Daniela Pimponi , Mauro Chinappi , Paolo Gualtieri , Carlo Massimo Casciola

Undulatory locomotion is ubiquitous in nature and observed in different media, from the swimming of flagellated microorganisms in biological fluids, to the slithering of snakes on land, or the locomotion of sandfish lizards in sand. Despite…

Fluid Dynamics · Physics 2017-01-03 Zhiwei Peng , On Shun Pak , Gwynn J. Elfring

Recent experiments on the green alga Chlamydomonas that swims using synchronized beating of a pair of flagella have revealed that it exhibits a run-and-tumble behavior similar to that of bacteria such as E. Coli. Using a simple purely…

Cell Behavior · Quantitative Biology 2015-06-12 Rachel R. Bennett , Ramin Golestanian

The motility of microorganisms is often biased by gradients in physical and chemical properties of their environment, with myriad implications on their ecology. Here we show that fluid acceleration reorients gyrotactic plankton, triggering…

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