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Geometric and structural constraints greatly restrict the selection of folds adapted by protein backbones, and yet, folded proteins show an astounding diversity in functionality. For structure to have any bearing on function, it is thus…

Biological Physics · Physics 2010-04-20 Brinda K. V. , Saraswathi Vishveshwara , Smitha Vishveshwara

Real-world complex systems exhibit intricate interconnections and dependencies, especially social networks, technological infrastructures, and communication networks. These networks are prone to disconnection due to random failures or…

Social and Information Networks · Computer Science 2025-05-23 Rajesh Kumar , Suchi Kumari , Anubhav Mishra

A detailed analysis of three species-rich ecosystem food webs has shown that they display scale-free distributions of connections. Such graphs of interaction are in fact shared by a number of biological and technological networks, which…

Disordered Systems and Neural Networks · Physics 2007-05-23 Ricard V. Sole Jose M. Montoya

Interdependent networks have been shown to be extremely vulnerable based on the percolation model. Parshani et. al further indicated that the more inter-similar networks are, the more robust they are to random failure. Our understanding of…

Physics and Society · Physics 2015-05-27 Fei Tan , Yongxiang Xia

Recent years have seen the world become a closely connected society with the emergence of different types of social networks. Online social networks have provided a way to bridge long distances and establish numerous communication channels…

Social and Information Networks · Computer Science 2014-11-03 Mohammad Ayub Latif , Muhammad Naveed , Faraz Zaidi

Complex networks have recently attracted much interest due to their prevalence in nature and our daily lives [1, 2]. A critical property of a network is its resilience to random breakdown and failure [3-6], typically studied as a…

Physics and Society · Physics 2016-01-08 James P. Bagrow , Sune Lehmann , Yong-Yeol Ahn

Protein structures can be studied as complex networks of interacting amino acids. We study proteins of different structural classes from the network perspective. Our results indicate that proteins, regardless of their structural class, show…

Molecular Networks · Quantitative Biology 2007-11-19 Ganesh Bagler , Somdatta Sinha

Complex networks often have a modular structure, where a number of tightly- connected groups of nodes (modules) have relatively few interconnections. Modularity had been shown to have an important effect on the evolution and stability of…

Physics and Society · Physics 2014-04-21 Saray Shai , Dror Y. Kenett , Yoed N. Kenett , Miriam Faust , Simon Dobson , Shlomo Havlin

Self-avoiding random walks were performed on protein residue networks. Compared with protein residue networks with randomized links, the probability of a walk being successful is lower and the length of successful walks shorter in…

Molecular Networks · Quantitative Biology 2013-06-11 Susan Khor

In light of the rise of malicious attacks on the Internet, and the various networks and applications attached to it, new approaches towards modeling predatory activity in networks could be useful. Past research has simulated networks…

Disordered Systems and Neural Networks · Physics 2007-05-23 Sean P. Gorman , Rajendra G. Kulkarni , Laurie A. Schintler , Roger R. Stough

Recently, the structural controllability theory has been introduced to analyze the Protein-Protein Interaction (PPI) network. The indispensable nodes, which their removal increase the number of driver nodes to control the network, are found…

Computational Physics · Physics 2016-09-12 Xizhe Zhang , Huaizhen Wang , Yunyi Yang

When an initial failure of nodes occurs in interdependent networks, a cascade of failure between the networks occurs. Earlier studies focused on random initial failures. Here we study the robustness of interdependent networks under targeted…

Physics and Society · Physics 2011-07-22 Xuqing Huang , Jianxi Gao , Sergey V. Buldyrev , Shlomo Havlin , H. Eugene Stanley

A networked dynamical system is composed of subsystems interconnected through prescribed interactions. In many engineering applications, however, one subsystem can also affect others through "unintended" interactions that can significantly…

Systems and Control · Electrical Eng. & Systems 2020-09-10 Yili Qian , Domitilla Del Vecchio

Molecular networks guide the biochemistry of a living cell on multiple levels: its metabolic and signalling pathways are shaped by the network of interacting proteins, whose production, in turn, is controlled by the genetic regulatory…

Soft Condensed Matter · Physics 2009-11-07 Sergei Maslov , Kim Sneppen

Since proteins carry out biological processes by interacting with other proteins, analyzing the structure of protein-protein interaction (PPI) networks could explain complex biological mechanisms, evolution, and disease. Similarly, studying…

Molecular Networks · Quantitative Biology 2010-04-22 Vesna Memisevic , Tijana Milenkovic , Natasa Przulj

Power-law networks such as the Internet, terrorist cells, species relationships, and cellular metabolic interactions are susceptible to node failures, yet maintaining network connectivity is essential for network functionality.…

Physics and Society · Physics 2015-05-08 Sarah LaRocca , Seth Guikema

Terrorist attacks on transportation networks have traumatized modern societies. With a single blast, it has become possible to paralyze airline traffic, electric power supply, ground transportation or Internet communication. How and at…

Physics and Society · Physics 2011-03-10 Christian M. Schneider , Andre A. Moreira , Jose S. Andrade , Shlomo Havlin , Hans J. Herrmann

Despite the huge interest in network resilience to stress, most of the studies have concentrated on internal stress damaging network structure (e.g., node removals). Here we study how networks respond to environmental stress deteriorating…

Physics and Society · Physics 2018-04-24 Young-Ho Eom

The structure of complex networks in previous research has been widely described as scale-free networks generated by the preferential attachment model. However, the preferential attachment model does not take into account the detailed…

Disordered Systems and Neural Networks · Physics 2008-02-26 Nobuhiko Oshida , Sigeo Ihara

While new forms of attacks are developed every day to compromise essential infrastructures, service providers are also expected to develop strategies to mitigate the risk of extreme failures. In this context, tools of Network Science have…

Physics and Society · Physics 2015-03-13 V. H. P. Louzada , F. Daolio , H. J. Herrmann , M. Tomassini
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