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This paper presents an interesting experimental example of voter-model statistics in biology. In recent work on mouse tail-skin, where proliferating cells are confined to a two-dimensional layer, we showed that cells proliferate and…

Biological Physics · Physics 2009-11-13 Allon M. Klein , David P. Doupe , Philip H. Jones , Benjamin D. Simons

Investigating the emergence of a particular cell type is a recurring theme in models of growing cellular populations. The evolution of resistance to therapy is a classic example. Common questions are: when does the cell type first occur,…

Populations and Evolution · Quantitative Biology 2019-06-19 Michael D. Nicholson , Tibor Antal

We study the Cauchy problem for a class of third order linear anisotropic evolution equations with complex valued lower order terms depending both on time and space variables. Under suitable decay assumptions for $|x| \to \infty$ on these…

Analysis of PDEs · Mathematics 2024-03-15 Alexandre Arias Junior , Alessia Ascanelli , Marco Cappiello

This paper presents a real-time simulation involving ''protozoan-like'' cells that evolve by natural selection in a physical 2D ecosystem. Selection pressure is exerted via the requirements to collect mass and energy from the surroundings…

Neural and Evolutionary Computing · Computer Science 2023-05-23 Dylan Cope

In this paper, we investigate the asymptotic behavior of solutions toward a multiwave pattern of the Cauchy problem for the scalar viscous conservation law where the far field states are prescribed. Especially, we deal with the case when…

Analysis of PDEs · Mathematics 2014-11-25 Natsumi Yoshida

The theory of weak solutions for nonlinear conservation laws is now well developed in the case of scalar equations [3] and for one-dimensional hyperbolic systems [1, 2]. For systems in several space dimensions, however, even the global…

Analysis of PDEs · Mathematics 2007-05-23 Alberto Bressan

In this article, we explore some of the main mathematical problems connected to multidimensional fractional conservation laws driven by L\'evy processes. Making use of an adapted entropy formulation, a result of existence and uniqueness of…

Analysis of PDEs · Mathematics 2019-04-25 Neeraj Bhauryal , Ujjwal Koley , Guy Vallet

The probability density functions (PDFs) for the solution of the incompressible Navier-Stokes equation can be represented by a hierarchy of linear equations. This article develops new hierarchical evolution equations for PDFs of a scalar…

Analysis of PDEs · Mathematics 2025-08-22 Qian Huang , Christian Rohde

We investigate a minimal model for cell propagation involving migration along self-generated signaling gradients and cell division, which has been proposed in an earlier study. The model consists in a system of two coupled parabolic…

Analysis of PDEs · Mathematics 2022-03-11 Mete Demircigil

This paper is concerned with the analysis of the Cauchy problem of a general class of two-dimensional nonlinear nonlocal wave equations governing anti-plane shear motions in nonlocal elasticity. The nonlocal nature of the problem is…

Analysis of PDEs · Mathematics 2020-08-04 H. A. Erbay , S. Erbay , A. Erkip

We analyze a replicator-mutator model arising in the context of directed evolution [23], where the selection term is modulated over time by the mean-fitness. We combine a Cumulant Generating Function approach [13] and a spatio-temporal…

Analysis of PDEs · Mathematics 2019-01-24 Matthieu Alfaro , Mario Veruete

We model and study the genetic evolution and conservation of a population of diploid hermaphroditic organisms, evolving continuously in time and subject to resource competition. In the absence of mutations, the population follows a 3-type…

Probability · Mathematics 2012-07-23 Camille Coron

Single-cell experiments have revealed cell-to-cell variability in generation times and growth rates for genetically identical cells. Theoretical models relating the fluctuating generation times of single cells to the population growth rate…

Populations and Evolution · Quantitative Biology 2020-01-15 Jie Lin , Ariel Amir

We study competition between two biological species advected by a compressible velocity field. Individuals are treated as discrete Lagrangian particles that reproduce or die in a density-dependent fashion. In the absence of a velocity field…

Populations and Evolution · Quantitative Biology 2012-04-24 Simone Pigolotti , Roberto Benzi , Mogens H. Jensen , David R. Nelson

We consider the Cauchy problem for a second-order evolution equation, in which the problem operator is the sum of two self-adjoint operators. The main feature of the problem is that one of the operators is represented in the form of the…

Numerical Analysis · Mathematics 2020-11-18 Petr N. Vabishchevich

The human ovary contains a fixed number of non-growing follicles (NGFs) established before birth that decline with increasing age culminating in the menopause at 50-51 years. The objective of this study is to model the age-related…

Tissues and Organs · Quantitative Biology 2011-06-08 W H B Wallace , T W Kelsey

We study regularity and decay properties for the solutions of the Cauchy problem for time-fractional partial differential equations, with tempered initial data, belonging to suitable (weighted) Sobolev spaces, associated with a differential…

Analysis of PDEs · Mathematics 2025-11-10 Sandro Coriasco , Giovanni Girardi , Stevan Pilipović

In this paper, we discuss the asymptotic behaviour of the weak solution to the Cauchy problem for the scalar viscous conservation law, with nonlinear Laplacian viscosity. Firstly, we obtain the existence, uniqueness and regularity of…

Analysis of PDEs · Mathematics 2023-12-07 Yechi Liu

We present a dimensionally split method for solving hyperbolic conservation laws on Cartesian cut cell meshes. The approach combines local geometric and wave speed information to determine a novel stabilised cut cell flux, and we provide a…

Computational Physics · Physics 2018-03-15 Nandan Gokhale , Nikos Nikiforakis , Rupert Klein

We present a space-time extension of a conservative Cartesian cut-cell finite-volume method for two-phase diffusion problems with prescribed interface motion. The formulation follows a two-fluid approach: one scalar field is solved in each…

Computational Physics · Physics 2026-01-01 Louis Libat , Can Selçuk , Eric Chénier , Vincent Le Chenadec