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In electronic health records (EHRs), latent subgroups of patients may exhibit distinctive patterning in their longitudinal health trajectories. For such data, growth mixture models (GMMs) enable classifying patients into different latent…

Methodology · Statistics 2022-01-12 Rebecca Anthopolos , Ying Wei , Qixuan Chen

Data collected in clinical trials are often composed of multiple types of variables. For example, laboratory measurements and vital signs are longitudinal data of continuous or categorical variables, adverse events may be recurrent events,…

Methodology · Statistics 2023-01-12 Tuo Wang , Rachel Zilinskas , Ying Li , Yongming Qu

Spatiotemporal data mining aims to discover interesting, useful but non-trivial patterns in big spatial and spatiotemporal data. They are used in various application domains such as public safety, ecology, epidemiology, earth science, etc.…

Databases · Computer Science 2022-06-28 Arun Sharma , Zhe Jiang , Shashi Shekhar

When confronting a spatio-temporal regression, it is sensible to feed the model with any available prior information about the spatial dimension. For example, it is common to define the architecture of neural networks based on spatial…

Machine Learning · Computer Science 2020-10-05 Rodrigo de Medrano , José L. Aznarte

Longitudinal binary relational data can be better understood by implementing a latent space model for dynamic networks. This approach can be broadly extended to many types of weighted edges by using a link function to model the mean of the…

Methodology · Statistics 2020-05-19 Daniel K. Sewell , Yuguo Chen

Advances in cellular imaging technologies, especially those based on fluorescence in situ hybridization (FISH) now allow detailed visualization of the spatial organization of human or bacterial cells. Quantifying this spatial organization…

Health surveys provide valuable information for monitoring population health, identifying risk factors and informing public health policies. Most of the questions included are coded as ordinal variables and organized into thematic blocks.…

Diverse analysis approaches have been proposed to distinguish data missing due to death from nonresponse, and to summarize trajectories of longitudinal data truncated by death. We demonstrate how these analysis approaches arise from…

Methodology · Statistics 2010-01-18 Brenda F. Kurland , Laura L. Johnson , Brian L. Egleston , Paula H. Diehr

In health cohort studies, repeated measures of markers are often used to describe the natural history of a disease. Joint models allow to study their evolution by taking into account the possible informative dropout usually due to clinical…

Joint models for longitudinal and time-to-event data have seen many developments in recent years. Though spatial joint models are still rare and the traditional proportional hazards formulation of the time-to-event part of the model is…

Methodology · Statistics 2024-06-25 Anja Rappl , Thomas Kneib , Stefan Lang , Elisabeth Bergherr

This paper investigates the modeling of an important class of degradation data, which are collected from a spatial domain over time; for example, the surface quality degradation. Like many existing time-dependent stochastic degradation…

Methodology · Statistics 2017-12-29 Xiao Liu , Kyongmin Yeo , Jayant Kalagnanam

End-stage renal disease has many adverse complications associated with it leading to 20-50% higher mortality rates in people than those without the disease. This makes it one of the leading causes of death in the United States. This article…

Applications · Statistics 2023-09-13 Supraja Malladi , Indranil Sahoo , QiQi Lu

This paper develops the inferential theory for latent factor models estimated from large dimensional panel data with missing observations. We propose an easy-to-use all-purpose estimator for a latent factor model by applying principal…

Econometrics · Economics 2022-01-11 Ruoxuan Xiong , Markus Pelger

Latent space models are powerful statistical tools for modeling and understanding network data. While the importance of accounting for uncertainty in network analysis has been well recognized, the current literature predominantly focuses on…

Statistics Theory · Mathematics 2025-08-15 Jinming Li , Shihao Wu , Chengyu Cui , Gongjun Xu , Ji Zhu

Discovering latent representations of the observed world has become increasingly more relevant in data analysis. Much of the effort concentrates on building latent variables which can be used in prediction problems, such as classification…

Machine Learning · Computer Science 2010-01-08 Ricardo Silva

Joint models for longitudinal biomarkers and time-to-event data are widely used in longitudinal studies. Many joint modeling approaches have been proposed to deal with different types of longitudinal biomarkers and survival outcomes.…

Methodology · Statistics 2016-09-27 Molei Liu , Jiehuan Sun , Jose D. Herazo-Maya , Naftali Kaminski , Hongyu Zhao

Spatial-temporal data modeling aims to mine the underlying spatial relationships and temporal dependencies of objects in a system. However, most existing methods focus on the modeling of spatial-temporal data in a single mode, lacking the…

Machine Learning · Computer Science 2023-08-23 Zihang Liu , Le Yu , Tongyu Zhu , Leiei Sun

Spatio-temporal prediction of levels of an environmental exposure is an important problem in environmental epidemiology. Our work is motivated by multiple studies on the spatio-temporal distribution of mobile source, or traffic related,…

Applications · Statistics 2014-11-14 Nikolay Bliznyuk , Christopher J. Paciorek , Joel Schwartz , Brent Coull

Unsupervised learning on imbalanced data is challenging because, when given imbalanced data, current model is often dominated by the major category and ignores the categories with small amount of data. We develop a latent variable model…

Machine Learning · Computer Science 2016-07-04 Fariba Yousefi , Zhenwen Dai , Carl Henrik Ek , Neil Lawrence

The purpose of this chapter is to discuss methods of acquisition, visualization and analysis of the dynamics of a complex biomedical system, illustrated by the human stomatognathic system. The stomatognathic system consists of the teeth and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Agnieszka A. Tomaka , Leszek Luchowski , Dariusz Pojda , Michał Tarnawski , Krzysztof Domino