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Intracellular protein patterns regulate many vital cellular functions, such as the processing of spatiotemporal information or the control of shape deformations. To do so, pattern-forming systems can be sensitive to the cell geometry by…

Biological Physics · Physics 2024-05-15 Tom Burkart , Benedikt J. Müller , Erwin Frey

Using Gauss's square-roots of the metric components, the diagonal Riemann tensor components for diagonal metrics are calculated. The result is a form which makes their source in the metric directly intuitive and displays an intriguing…

General Mathematics · Mathematics 2019-02-06 Avi Rabinowitz

The growth function of populations is central in biomathematics. The main dogma is the existence of density dependence mechanisms, which can be modelled with distinct functional forms that depend on the size of the population. One important…

Populations and Evolution · Quantitative Biology 2010-10-15 Harold P. de Vladar

Inhomogeneities in deposition may lead to formation of rough surfaces, whose height fluctuations can be probed directly by scanning microscopy, or indirectly by scattering. Analytical or numerical treatments of simple growth models suggest…

Condensed Matter · Physics 2009-10-28 Mehran Kardar

We illustrate the flow or wave character of the metrics and curvatures of evolving manifolds, introducing the Riemann flow and the Riemann wave via the bialternate product Riemannian metric. This kind of evolutions are new and very natural…

Analysis of PDEs · Mathematics 2012-10-22 Constantin Udriste

In recent years, manifold learning has become increasingly popular as a tool for performing non-linear dimensionality reduction. This has led to the development of numerous algorithms of varying degrees of complexity that aim to recover man…

Machine Learning · Statistics 2013-06-03 Dominique Perraul-Joncas , Marina Meila

I describe the manifestation of the non-Euclidean geometry in the behavior of collective observables of some complex physical systems. Specifically, I consider the formation of equilibrium shapes of plants and statistics of sparse random…

Soft Condensed Matter · Physics 2017-05-30 Sergei Nechaev

The material structure of bodies undergoing growth is considered. In the geometric framework of a general differential manifold modeling the physical space and a fiber bundle modeling spacetime, body points may be defined for any extensive…

Mathematical Physics · Physics 2023-11-14 Vladimir Goldshtein , Reuven Segev

The complexity of gene regulatory networks in multicellular organisms makes interpretable low-dimensional models highly desirable. An attractive geometric picture, attributed to Waddington, visualizes the differentiation of a cell into…

Biological Physics · Physics 2024-12-12 Gautam Reddy

In this paper we consider the 2-component reaction-diffusion model that was recently obtained by a systematic reduction of the 3-component Gilad et al. model for dryland ecosystem dynamics. The nonlinear structure of this model is more…

Dynamical Systems · Mathematics 2020-08-26 Olfa Jaibi , Arjen Doelman , Martina Chirilus-Bruckner , Ehud Meron

Shape affects both the physical and chemical properties of a material. Characterizing the roughness, convexity, and general geometry of a material can yield information on its catalytic efficiency, solubility, elasticity, porosity, and…

Computational Engineering, Finance, and Science · Computer Science 2023-09-18 Alexander Smith , Steven Schilling , Prodromos Daoutidis

The sessile microbial communities known as biofilms exhibit varying architectures as environmental factors are varied, which for immersed biofilms includes the shear rate of the surrounding flow. Here we modify an established agent-based…

Biological Physics · Physics 2014-03-11 D. A. Head

We discuss a general growth curve including several parameters, whose choice leads to a variety of models including the classical cases of Malthusian, Richards, Gompertz, Logistic and some their generalizations. The advantage is to obtain a…

Statistical Mechanics · Physics 2024-02-05 G. Albano , V. Giorno , P. Román-Román , F. Torres-Ruiz

We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…

Analysis of PDEs · Mathematics 2015-06-22 Donatella Donatelli , Konstantina Trivisa

We study the effect of fluid flow on three-dimensional (3D) dendrite growth using a phase-field model on an adaptive finite element grid. In order to simulate 3D fluid flow, we use an averaging method for the flow problem coupled to the…

Materials Science · Physics 2009-11-07 Jun-Ho Jeong , Nigel Goldenfeld , Jonathan A. Dantzig

We have studied the growth kinetics of isolated precipitates growing from a supersaturated matrix in 3-dimensions (3-D) using phase field models; we assume isotropic interfacial energy consider both constant and variable diffusivity. We…

Materials Science · Physics 2014-12-23 Arijit Roy , Mogadalai P Gururajan

In this paper we present a study of local dynamics of the growth of cancer tumor and healthy cells considering the presence of nutrients in the system. We also analyze the evolution of system if we take indirectly into account the level of…

Biological Physics · Physics 2019-01-29 Cristian C. Pérez Águila , Maura Cárdenas G. , J. Fernando Rojas

By unifying three foundational principles of modern biology, we develop a mathematical framework to analyze the growing tree of life. Contrary to the static case, where the analogy between phylogenetic trees and the tree that grows in soil…

Populations and Evolution · Quantitative Biology 2025-10-01 Kevin Hudnall , Raissa D'Souza

We present significantly advanced studies of the previously introduced physical growth mechanism and unite it with biochemical growth factors. Obtained results allowed formulating the general growth law which governs growth and evolutional…

Other Quantitative Biology · Quantitative Biology 2012-11-29 Yu. K. Shestopaloff

We give a very short introduction to discrete and continuum models for the evolutionary and spatial dynamics of cancer through two case studies: a model for the evolutionary dynamics of cancer cells under cytotoxic therapy and a model for…

Tissues and Organs · Quantitative Biology 2019-11-07 Tommaso Lorenzi , Fiona R. Macfarlane , Chiara Villa