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Imaging biomarkers in neuro-oncology are used for diagnosis, prognosis and treatment response monitoring. Magnetic resonance imaging is typically used throughout the patient pathway because routine structural imaging provides detailed…

Quantitative Methods · Quantitative Biology 2019-10-21 Thomas Booth

Interpretable insights from predictive models remain critical in bio-statistics, particularly when assessing causality, where classical statistical and machine learning methods often provide inherent clarity. While Neural Networks (NNs)…

Applications · Statistics 2025-05-02 Jean-Baptiste A. Conan

There has been significant focus on creating neuro-symbolic models for interpretable image classification using Convolutional Neural Networks (CNNs). These methods aim to replace the CNN with a neuro-symbolic model consisting of the CNN,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Parth Padalkar , Jaeseong Lee , Shiyi Wei , Gopal Gupta

Deep Neural Networks (DNNs) do not inherently compute or exhibit empirically-justified task confidence. In mission critical applications, it is important to both understand associated DNN reasoning and its supporting evidence. In this…

Machine Learning · Computer Science 2024-03-14 Paul Ardis , Arjuna Flenner

The symptom checking systems inquire users for their symptoms and perform a rapid and affordable medical assessment of their condition. The basic symptom checking systems based on Bayesian methods, decision trees, or information gain…

Computation and Language · Computer Science 2022-06-03 Aleksandr Nesterov , Bulat Ibragimov , Dmitriy Umerenkov , Artem Shelmanov , Galina Zubkova , Vladimir Kokh

Deep learning as represented by the artificial deep neural networks (DNNs) has achieved great success in many important areas that deal with text, images, videos, graphs, and so on. However, the black-box nature of DNNs has become one of…

Machine Learning · Computer Science 2021-09-29 Fenglei Fan , Jinjun Xiong , Mengzhou Li , Ge Wang

We introduce LearnAD, a neuro-symbolic method for predicting Alzheimer's disease from brain magnetic resonance imaging data, learning fully interpretable rules. LearnAD applies statistical models, Decision Trees, Random Forests, or GNNs to…

Machine Learning · Computer Science 2026-01-06 Thomas Andrews , Mark Law , Sara Ahmadi-Abhari , Alessandra Russo

The ability to interpret machine learning models has become increasingly important now that machine learning is used to inform consequential decisions. We propose an approach called model extraction for interpreting complex, blackbox…

Machine Learning · Computer Science 2018-03-14 Osbert Bastani , Carolyn Kim , Hamsa Bastani

Deep neural networks have emerged as the workhorse for a large section of robotics and control applications, especially as models for dynamical systems. Such data-driven models are in turn used for designing and verifying autonomous…

Machine Learning · Computer Science 2023-11-08 Kaustubh Sridhar , Souradeep Dutta , James Weimer , Insup Lee

In many practical applications, deep neural networks have been typically deployed to operate as a black box predictor. Despite the high amount of work on interpretability and high demand on the reliability of these systems, they typically…

Artificial Intelligence · Computer Science 2020-12-07 Martin Stano , Wanda Benesova , Lukas Samuel Martak

Large language models (LLMs) continue to face challenges in reliably solving reasoning tasks, particularly those that require precise rule following, as often found in mathematical reasoning. This paper introduces a novel neurosymbolic…

Machine Learning · Computer Science 2025-11-19 Varun Dhanraj , Chris Eliasmith

Nonlinear methods such as Deep Neural Networks (DNNs) are the gold standard for various challenging machine learning problems, e.g., image classification, natural language processing or human action recognition. Although these methods…

Machine Learning · Computer Science 2017-11-15 Grégoire Montavon , Sebastian Bach , Alexander Binder , Wojciech Samek , Klaus-Robert Müller

Deep neural networks (DNNs) are powerful black-box predictors that have achieved impressive performance on a wide variety of tasks. However, their accuracy comes at the cost of intelligibility: it is usually unclear how they make their…

Machine Learning · Computer Science 2021-10-26 Rishabh Agarwal , Levi Melnick , Nicholas Frosst , Xuezhou Zhang , Ben Lengerich , Rich Caruana , Geoffrey Hinton

Machine learning-based methods have achieved successful applications in machinery fault diagnosis. However, the main limitation that exists for these methods is that they operate as a black box and are generally not interpretable. This…

Machine Learning · Computer Science 2022-04-20 Gang Chen , Yu Lu , Rong Su , Zhaodan Kong

Neural networks are commonly regarded as black boxes performing incomprehensible functions. For classification problems networks provide maps from high dimensional feature space to K-dimensional image space. Images of training vector are…

Neural and Evolutionary Computing · Computer Science 2018-02-26 Wlodzislaw Duch

In this paper we investigate formal verification of extracted rules for Neural Networks under a complexity theoretic point of view. A rule is a global property or a pattern concerning a large portion of the input space of a network. These…

Artificial Intelligence · Computer Science 2025-09-23 Adrian Wurm

Neural networks have a reputation for being better at solving statistical or approximate problems than at performing calculations or working with symbolic data. In this paper, we show that they can be surprisingly good at more elaborated…

Symbolic Computation · Computer Science 2019-12-04 Guillaume Lample , François Charton

Deep Learning has emerged as one of the most significant innovations in machine learning. However, a notable limitation of this field lies in the ``black box" decision-making processes, which have led to skepticism within groups like…

Machine Learning · Computer Science 2025-03-06 Shi Li

Artificial Neural Network is among the most popular algorithm for supervised learning. However, Neural Networks have a well-known drawback of being a "Black Box" learner that is not comprehensible to the Users. This lack of transparency…

Machine Learning · Computer Science 2011-10-04 Ridwan Al Iqbal

A major challenge in designing neural network (NN) systems is to determine the best structure and parameters for the network given the data for the machine learning problem at hand. Examples of parameters are the number of layers and nodes,…

Artificial Intelligence · Computer Science 2017-05-25 Gonzalo Diaz , Achille Fokoue , Giacomo Nannicini , Horst Samulowitz