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Active gels perform key mechanical roles inside the cell, such as cell division, motion and force sensing. The unique mechanical properties required to perform such functions arise from the interactions between molecular motors and…

Soft Condensed Matter · Physics 2022-08-16 Andrés Córdoba

We use Langevin dynamics simulations to study dynamical behaviour of a dense planar layer of active semi-flexible filaments. Using the strength of active force and the thermal persistence length as parameters, we map a detailed phase…

Soft Condensed Matter · Physics 2018-02-21 K. R. Prathyusha , Silke Henkes , Rastko Sknepnek

In equilibrium, the physical properties of matter are set by the interactions between the constituents. In contrast, the energy input of the individual components controls the behavior of synthetic or living active matter. Great progress…

Soft Condensed Matter · Physics 2025-08-29 Q. Martinet , Y. Li , A. Aubret , E. Hannezo , J. Palacci

Molecular-motor generated active stresses drive the cytoskeleton away from equilibrium, endowing it with tunable mechanical properties that are essential for diverse functions such as cell division and motility[1-5]. Designing analogous…

Continuum models of active nematic gels have proved successful to describe a number of biological systems consisting of a population of rodlike motile subunits in a fluid environment. However, in order to get a thorough understanding of the…

Soft Condensed Matter · Physics 2023-05-03 Stefano Turzi

Active forces occurring within cells can drive crucial biological processes that involve spontaneous organization and shape change, such as cell division. Motivated by recent in vitro experiments of nematic droplets of cytoskeletal…

Soft Condensed Matter · Physics 2021-02-16 Fabian Jan Schwarzendahl , Pierre Ronceray , Kimberly L. Weirich , Kinjal Dasbiswas

Robust self-organization of subcellular structures is a key principle governing the dynamics and evolution of cellular life. In fission yeast cells undergoing division, the mitotic spindle spontaneously emerges from the interaction of…

Soft Condensed Matter · Physics 2024-06-03 David A. Head , W. J. Briels , Gerhard Gompper

Recent experiments on active materials, such as dense bacterial suspensions and microtubule-kinesin motor mixtures, show a promising potential for achieving self-sustained flows. However, to develop active microfluidics it is necessary to…

Soft Condensed Matter · Physics 2019-01-23 Santhan Chandragiri , Amin Doostmohammadi , Julia M Yeomans , Sumesh P Thampi

We present a continuum level analytical model of a droplet of active contractile fluid consisting of filaments and motors. We calculate the steady state flows that result from a splayed polarisation of the filaments. We account for the…

Cell Behavior · Quantitative Biology 2014-02-20 Carl A. Whitfield , Davide Marenduzzo , Raphaël Voituriez , Rhoda J. Hawkins

We study the dynamics of an entangled, isotropic solution of polar filaments coupled by molecular motors which generate relative motion of the filaments in two and three dimensions. We investigate the stability of the homogeneous state for…

Soft Condensed Matter · Physics 2009-11-07 Tanniemola B. Liverpool , M. Cristina Marchetti

We propose a theory based on non-equilibrium thermodynamics to describe the mechanical behavior of an active polymer gel created by the inclusion of molecular motors in its solvent. When activated, these motors attach to the chains of the…

Soft Condensed Matter · Physics 2019-05-31 Mattia Bacca , Omar A. Saleh , Robert M. McMeeking

Many natural and industrial processes rely on constrained transport, such as proteins moving through cells, particles confined in nanocomposite materials or gels, individuals in highly dense collec- tives and vehicular traffic conditions.…

The movement of motor particles consisting of one or several molecular motors bound to a cargo particle is studied theoretically. The particles move on patterns of immobilized filaments. Several patterns are described for which the motor…

Statistical Mechanics · Physics 2009-11-11 Stefan Klumpp , Reinhard Lipowsky

We derive the constitutive equations of an active polar gel from a model for the dynamics of elastic molecules that link polar elements. Molecular binding kinetics induces the fluidization of the material, giving rise to Maxwell…

Biological Physics · Physics 2017-03-01 David Oriola , Ricard Alert , Jaume Casademunt

I put forward a continuum theory for active nematic gels, defined as fluids or suspensions of orientable rodlike objects endowed with active dynamics, that is based on symmetry arguments and compatibility with thermodynamics. The starting…

Soft Condensed Matter · Physics 2017-11-15 Stefano S Turzi

We simulate the nonlocal Stokesian hydrodynamics of an elastic filament which is active due a permanent distribution of stresslets along its contour. A bending instability of an initially straight filament spontaneously breaks flow symmetry…

Active colloids and externally actuated semi-flexible filaments provide basic building blocks for designing autonomously motile micro-machines. Here, we show that a passive semi-flexible filament can be actuated and transported by attaching…

Soft Condensed Matter · Physics 2017-04-05 Abhrajit Laskar , R. Adhikari

We study a simple two-dimensional model for motion of an elastic filament subject to internally generated stresses and show that wave-like propagating shapes which can propel the filament can be induced by a self-organized mechanism via a…

Soft Condensed Matter · Physics 2019-08-17 S. Camalet , F. Julicher , J. Prost

Active semiflexible filaments are crucial in various biophysical processes, yet insights into their single-filament behavior have predominantly relied on theory and simulations, owing to the scarcity of controllable synthetic systems. Here,…

Soft Condensed Matter · Physics 2025-07-14 Bipul Biswas , Prasanna More , Hima Nagamanasa Kandula

Magnetic gels with embedded micro/nano-sized magnetic particles in crosslinked polymer networks can be actuated by external magnetic fields, with changes in their internal microscopic structures and macroscopic mechanical properties. We…

Soft Condensed Matter · Physics 2024-03-21 Xuefeng Wei , Gaspard Junot , Ramin Golestanian , Xin Zhou , Yanting Wang , Pietro Tierno , Fanlong Meng