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The molecular biology revolution of the last seventy five years has transformed our view of living systems. Scientific explanations of biological phenomena are now synonymous with the identification of the genes, proteins, and signaling…

Biological Physics · Physics 2024-10-29 Pankaj Mehta

The study of neural computation aims to understand the function of a neural system as an information processing machine. Neural systems are undoubtedly complex, necessitating principled and automated tools to abstract away details to…

Dynamical Systems · Mathematics 2025-07-09 Abel Sagodi , Il Memming Park

We create a novel optimisation technique inspired by natural ecosystems, where the optimisation works at two levels: a first optimisation, migration of genes which are distributed in a peer-to-peer network, operating continuously in time;…

Neural and Evolutionary Computing · Computer Science 2012-11-26 Gerard Briscoe , Philippe De Wilde

This chapter does not deal with specific tools and techniques for managing complex systems, but proposes some basic concepts that help us to think and speak about complexity. We review classical thinking and its intrinsic drawbacks when…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Carlos Gershenson , Francis Heylighen

Self-organization offers a promising approach for designing adaptive systems. Given the inherent complexity of most cyber-physical systems, adaptivity is desired, as predictability is limited. Here I summarize different concepts and…

Multiagent Systems · Computer Science 2026-02-04 Carlos Gershenson

Emergent processes in complex systems such as cellular automata can perform computations of increasing complexity, and could possibly lead to artificial evolution. Such a feat would require scaling up current simulation sizes to allow for…

Cellular Automata and Lattice Gases · Physics 2021-04-05 Hugo Cisneros , Josef Sivic , Tomas Mikolov

Biological systems perform an astonishing array of dynamical processes -- including development and repair, regulation, behavior and motor control, sensing and signaling, and adaptation, among others. Powered by the transduction of stored…

Soft Condensed Matter · Physics 2025-09-04 James Clarke , Jake McGrath , Colin Johnson , José Alvarado

The study of biological cells in terms of mesoscopic, nonequilibrium, nonlinear, stochastic dynamics of open chemical systems provides a paradigm for other complex, self-organizing systems with ultra-fast stochastic fluctuations, short-time…

Chemical Physics · Physics 2014-11-06 Hong Qian

Biological systems are generally complicated and/or complex. In the former approach, one sets up a model with a large number of parameters to describe the system in detail. The latter approach focuses on understanding the universal aspects…

Biological Physics · Physics 2026-03-19 Kunihiko Kaneko

Cellular automata are arrays of finite state machines that can exist in a finite number of states. These machines update their states simultaneously based on specific local rules that govern their interactions. This framework provides a…

Cellular Automata and Lattice Gases · Physics 2025-08-11 Genaro J. Martinez , Andrew Adamatzky , Guanrong Chen

Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…

Other Quantitative Biology · Quantitative Biology 2024-04-17 Daniel Koch , Akhilesh Nandan , Gayathri Ramesan , Aneta Koseska

We argue that traditional Western science cannot adequately describe sports and other types of human behavior. Then we make an argument why a complex adaptive systems approach has the potential to provide the foundation for such a theory.…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Gottfried Mayer-Kress

Despite their potential to address crucial bottlenecks in computing architectures and contribute to the pool of biological inspiration for engineering, pathological biological mechanisms remain absent from computational theory. We hereby…

Neural and Evolutionary Computing · Computer Science 2025-03-18 Rosalia Moreddu , Michael Levin

Evolutionary and bioinspired computation are crucial for efficiently addressing complex optimization problems across diverse application domains. By mimicking processes observed in nature, like evolution itself, these algorithms offer…

Neural and Evolutionary Computing · Computer Science 2025-01-14 Daniel Molina , Javier Del Ser , Javier Poyatos , Francisco Herrera

The past century has seen a steady increase in the need of estimating and predicting complex systems and making (possibly critical) decisions with limited information. Although computers have made possible the numerical evaluation of…

Statistics Theory · Mathematics 2017-01-13 Houman Owhadi , Clint Scovel

Despite being optimized, the information processing of biological organisms exhibits significant variability in its complexity and capability. One potential source of this diversity is the limitation of resources required for information…

Biological Physics · Physics 2025-10-21 Takehiro Tottori , Tetsuya J. Kobayashi

Abbreviated Abstract: The objective of Evolutionary Computation is to solve practical problems (e.g. optimization, data mining) by simulating the mechanisms of natural evolution. This thesis addresses several topics related to adaptation…

Neural and Evolutionary Computing · Computer Science 2009-07-06 James M Whitacre

Achieving advanced machine intelligence remains a central challenge in AI research, often approached through scaling neural architectures and generative models. However, biological systems offer a broader repertoire of strategies for…

Neurons and Cognition · Quantitative Biology 2026-05-26 Giovanni Pezzulo , Michael Levin

Computation is commonly defined as the execution of abstract algorithms over symbolic representations, with physical systems treated as substrates that realise predefined operations. While effective for engineered machines, this separation…

Physics and Society · Physics 2026-01-21 Kimia Witte

Synthetic biology is a recent area of biological engineering, whose aim is to provide cells with novel functionalities. A number of important results regarding the development of control circuits in synthetic biology have been achieved…

Systems and Control · Electrical Eng. & Systems 2024-11-11 Antón Pardo , Sandra Díaz Seoane , Dorin A. Ionescu , Antonis Papachristodoulou , Alejandro F. Villaverde
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