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The proper functioning of multicellular organisms requires the robust establishment of precise proportions between distinct cell-types. This developmental differentiation process typically involves intracellular regulatory and stochastic…

Cell Behavior · Quantitative Biology 2016-06-22 Benjamin Pfeuty , Kunihiko Kaneko

Cilia and flagella often exhibit synchronized behavior; this includes phase locking, as seen in {\it Chlamydomonas}, and metachronal wave formation in the respiratory cilia of higher organisms. Since the observations by Gray and Rothschild…

Soft Condensed Matter · Physics 2016-05-19 Kirsty Y. Wan , Raymond E. Goldstein

Many biological systems synchronize their movement through physical interactions. By far the most well studied examples concern physical interactions through a fluid: beating cilia, swimming sperm and worms, and flapping wings, all display…

Adaptation and Self-Organizing Systems · Physics 2021-09-15 Wei Zhou , Zhuonan Hao , Nick Gravish

We study the synchronization of a small-world network of identical coupled phase oscillators with Kuramoto interaction. First, we consider the model with instantaneous mutual interaction and the normalized coupling constant to the degree of…

Disordered Systems and Neural Networks · Physics 2017-05-23 Sara Ameli , Farhad Shahbazi , Maryam Karimian , Tahereh Malakoutikhah

Human cognition emerges from coordinated spiking dynamics in distributed neural circuits, where information is encoded via both firing rates and precise spike timing determined by brain rhythms. Inspired by this notion, we propose a…

Neurons and Cognition · Quantitative Biology 2026-05-05 Tingting Dan , Guorong Wu

We study the effect of coupling delay in a regular network with a ring topology and in a more complex network with an all-to-all (global) topology in the presence of impurities (disorder). We find that the coupling delay is capable of…

Chaotic Dynamics · Physics 2011-12-26 D. V. Senthilkumar , R. Suresh , Jane H. Sheeba , M. Lakshmanan , J. Kurths

Some microorganisms, such as spermatozoa, synchronize their flagella when swimming in close proximity. Using a simplified model (two infinite, parallel, two-dimensional waving sheets), we show that phase-locking arises from hydrodynamics…

Biological Physics · Physics 2009-09-15 Gwynn J. Elfring , Eric Lauga

Small lattices of $N$ nearest neighbor coupled excitable FitzHugh-Nagumo systems, with time-delayed coupling are studied, and compared with systems of FitzHugh-Nagumo oscillators with the same delayed coupling. Bifurcations of equilibria in…

Chaotic Dynamics · Physics 2009-11-10 Nikola Buric , Dragana Todorovic

We present an analytical and numerical study of the coherent exciton polarization including exciton-exciton correlation. The time evolution after excitation with ultrashort optical pulses can be divided into a slowly varying polarization…

Condensed Matter · Physics 2009-10-31 Th. Oestreich , L. J. Sham

The oscillatory dynamics of natural and man-made systems can be disrupted by their time-varying interactions, leading to oscillation quenching phenomena in which the oscillations are suppressed. We introduce a framework for analyzing,…

Adaptation and Self-Organizing Systems · Physics 2025-11-19 Dushko Stavrov , Aneta Koseska , Tomislav Stankovski

We consider the effect of distributed delays in neural feedback systems. The avian optic tectum is reciprocally connected with the nucleus isthmi. Extracellular stimulation combined with intracellular recordings reveal a range of signal…

Biological Physics · Physics 2007-12-04 Ulrike Meyer , Jing Shao , Saurish Chakrabarty , Sebastian F. Brandt , Harald Luksch , Ralf Wessel

Rhythmic and sequential segmentation of the embryonic body plan is a vital developmental patterning process in all vertebrate species. However, a theoretical framework capturing the emergence of dynamic patterns of gene expression from the…

Biological Physics · Physics 2016-10-12 David J. Jörg , Andrew C. Oates , Frank Jülicher

Since the earliest electroencephalography experiments, large scale oscillations have been observed in the mammalian brain. More recently, episodes of oscillation and bursting have been identified not only in the cerebral cortex and…

Neurons and Cognition · Quantitative Biology 2025-09-03 Daniel Pouzzner

It is known that an identical delay in all transmission lines can destabilize macroscopic stationarity of a neural network, causing oscillation or chaos. We analyze the collective dynamics of a network whose intra-transmission delays are…

Disordered Systems and Neural Networks · Physics 2011-11-10 Takahiro Omi , Shigeru Shinomoto

Despite their significant functional roles, beta-band oscillations are least understood. Synchronization in neuronal networks have attracted much attention in recent years with the main focus on transition type. Whether one obtains…

Adaptation and Self-Organizing Systems · Physics 2018-10-22 Mahsa Khoshkhou , Afshin Montakhab

This study explores a method to characterize temporal structure of intermittent phase locking in oscillatory systems. When an oscillatory system is in a weakly synchronized regime away from a synchronization threshold, it spends most of the…

Dynamical Systems · Mathematics 2011-09-21 Sungwoo Ahn , Choongseok Park , Leonid L. Rubchinsky

In metazoans, cells collectively polarize and align along the tissue plane. This phenomenon is called Planar cell polarity (PCP). Polarization means asymmetric segregation of molecules and sub-cellular structures within a cell. In PCP,…

Adaptation and Self-Organizing Systems · Physics 2023-08-22 Talagadadeevi Nirupamateja , Siva Sai Himakar Sreerangam , Biplab Bose

Causal ordering of key events in the cell cycle is essential for proper functioning of an organism. Yet, it remains a mystery how a specific temporal program of events is maintained despite ineluctable stochasticity in the biochemical…

Molecular Networks · Quantitative Biology 2017-03-30 Farshid Jafarpour , Michael Vennettilli , Srividya Iyer-Biswas

DNA methylation is a primary layer of epigenetic modification that plays a pivotal role in the regulation of development, aging, and cancer. The concurrent activity of opposing enzymes that mediate DNA methylation and demethylation gives…

Biological Physics · Physics 2026-02-10 Fabrizio Olmeda , Misha Gupta , Onurcan Bektas , Steffen Rulands

Synchronized oscillations are of critical functional importance in many biological systems. We show that such oscillations can arise without centralized coordination in a disordered system of electrically coupled excitable and passive…

Adaptation and Self-Organizing Systems · Physics 2015-06-03 Rajeev Singh , Jinshan Xu , Nicolas Garnier , Alain Pumir , Sitabhra Sinha