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Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

Artificial Intelligence · Computer Science 2025-04-01 Sarah Martinson , Lingkai Kong , Cheol Woo Kim , Aparna Taneja , Milind Tambe

Epidemic models are used to analyze the progression or outcome of an epidemic under different control policies like vaccinations, quarantines, lockdowns, use of face-masks, pharmaceutical interventions, etc. When these models accurately…

Quantitative Methods · Quantitative Biology 2022-04-19 Carlos Hernandez-Suarez , Osval Montsinos Lopez , Ramon Solano-Barajas

In this work we demonstrate how to automate parts of the infectious disease-control policy-making process via performing inference in existing epidemiological models. The kind of inference tasks undertaken include computing the posterior…

The sensory contact model allows forming different psychopathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, hypersensitivity, cognition disturbances, anhedonia, alcoholism etc.) produced by…

Other Quantitative Biology · Quantitative Biology 2008-05-21 N. N. Kudryavtseva , D. F. Avgustinovich , N. P. Bondar , M. V. Tenditnik , I. L. Kovalenko , L. A. Koryakina

Accurate models of clinical actions and their impacts on disease progression are critical for estimating personalized optimal dynamic treatment regimes (DTRs) in medical/health research, especially in managing chronic conditions.…

Methodology · Statistics 2021-02-19 William Hua , Hongyuan Mei , Sarah Zohar , Magali Giral , Yanxun Xu

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

Artificial Intelligence · Computer Science 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Conventional likelihood-based information criteria for model selection rely on the distribution assumption of data. However, for complex data that are increasingly available in many scientific fields, the specification of their underlying…

Methodology · Statistics 2020-06-25 Chixiang Chen , Ming Wang , Rongling Wu , Runze Li

A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be…

Machine Learning · Statistics 2016-07-07 Yingfei Wang , Warren Powell

Estimating counterfactual outcomes over time has the potential to unlock personalized healthcare by assisting decision-makers to answer ''what-iF'' questions. Existing causal inference approaches typically consider regular, discrete-time…

Machine Learning · Computer Science 2022-06-17 Nabeel Seedat , Fergus Imrie , Alexis Bellot , Zhaozhi Qian , Mihaela van der Schaar

This article describes a method to estimate the mortality rate ratio R from current status data with duration in a chronic condition in case the general mortality of the overall population is known. Apart from the general mortality, the…

Methodology · Statistics 2022-10-21 Ralph Brinks

Social dynamics is concerned primarily with interactions among individuals and the resulting group behaviors, modeling the temporal evolution of social systems via the interactions of individuals within these systems. In particular, the…

Machine Learning · Statistics 2016-11-08 Zhen Xu , Wen Dong , Sargur Srihari

The news coverage of events often contains not one but multiple incompatible accounts of what happened. We develop a query-based system that extracts compatible sets of events (scenarios) from such data, formulated as one-class clustering.…

Computation and Language · Computer Science 2019-09-17 Su Wang , Greg Durrett , Katrin Erk

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

With the increased availability of large databases of electronic health records (EHRs) comes the chance of enhancing health risks screening. Most post-marketing detections of adverse drug reaction (ADR) rely on physicians' spontaneous…

Applications · Statistics 2018-01-29 Maryan Morel , Emmanuel Bacry , Stéphane Gaïffas , Agathe Guilloux , Fanny Leroy

Policy makers typically face the problem of wanting to estimate the long-term effects of novel treatments, while only having historical data of older treatment options. We assume access to a long-term dataset where only past treatments were…

Econometrics · Economics 2022-02-11 Keith Battocchi , Eleanor Dillon , Maggie Hei , Greg Lewis , Miruna Oprescu , Vasilis Syrgkanis

Health informatics can inform decisions that practitioners, patients, policymakers, and researchers need to make about health and disease. Health informatics is built upon patient health data leading to the need to codify patient health…

Computers and Society · Computer Science 2023-04-14 Jacob S. Zelko , Sarah Gasman , Shenita R. Freeman , Dong Yun Lee , Jaan Altosaar , Azza Shoaibi , Gowtham Rao

Human communication is commonly represented as a temporal social network, and evaluated in terms of its uniqueness. We propose a set of new entropy-based measures for human communication dynamics represented within the temporal social…

Social and Information Networks · Computer Science 2018-10-29 Marcin Kulisiewicz , Przemysław Kazienko , Bolesław K. Szymański , Radosław Michalski

A model based on a thermodynamic approach is proposed for predicting the dynamics of communicable epidemics in a city, when the epidemic is governed by controlling efforts of multiple scales so that an entropy is associated with the system.…

Medical Physics · Physics 2013-10-01 W. B. Wang , Z. N. Wu , Z. M. Cao , R. F. Hu

Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with…

Populations and Evolution · Quantitative Biology 2022-01-31 Jason Hindes , Michael Assaf , Ira B. Schwartz

A new approach to Dynamical Monte Carlo Methods is introduced to simulate markovian processes. We apply this approach to formulate and study an epidemic Generalized SIRS model. The results are in excellent agreement with the forth order…

Computational Physics · Physics 2009-11-07 O. E. Aiello , Marco A. A. da Silva