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Related papers: A Novel Chronic Disease Policy Model

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Inferring models, predicting the future, and estimating the entropy rate of discrete-time, discrete-event processes is well-worn ground. However, a much broader class of discrete-event processes operates in continuous-time. Here, we provide…

Statistical Mechanics · Physics 2020-05-11 S. E. Marzen , J. P. Crutchfield

Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a…

Machine Learning · Computer Science 2025-03-04 Haoyu Yang , Sanjoy Dey , Pablo Meyer

Clinical event sequences consist of thousands of clinical events that represent records of patient care in time. Developing accurate prediction models for such sequences is of a great importance for defining representations of a patient…

Machine Learning · Computer Science 2021-04-07 Jeong Min Lee , Milos Hauskrecht

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the most part of human diseases and include those with largest prevalence and mortality (cancer, heart disease, obesity, etc.).…

Quantitative Methods · Quantitative Biology 2009-05-08 Roberto Amato , Michele Pinelli , Daniel D'Andrea , Gennaro Miele , Mario Nicodemi , Giancarlo Raiconi , Sergio Cocozza

Dynamic microsimulation has long been recognized as a powerful tool for policy analysis, but in fact most major health policy simulations lack path dependency, a critical feature for evaluating policies that depend on accumulated outcomes…

Applications · Statistics 2025-06-04 Adrienne M. Propp , Raffaele Vardavas , Carter C. Price , Kandice A. Kapinos

The challenges posed by epidemics and pandemics are immense, especially if the causes are novel. This article introduces a versatile open-source simulation framework designed to model intricate dynamics of infectious diseases across diverse…

Multiagent Systems · Computer Science 2023-11-17 Zenin Easa Panthakkalakath , Neeraj , Jimson Mathew

Discrete and Continuous Dynamics is the first in a series of articles on Network Models for Epidemiology. This project began in the Fall quarter of 2014 in my continuous modeling course. Since then, it has taken off and turned into a series…

Populations and Evolution · Quantitative Biology 2015-11-04 Edward Rusu

In this paper, we propose a maximum entropy method for predicting disease risks. It is based on a patient's medical history with diseases coded in ICD-10 which can be used in various cases. The complete algorithm with strict mathematical…

Machine Learning · Computer Science 2021-02-05 Michael Shub , Qing Xu , Xiaohua , Xuan

This paper investigates the spread of infectious diseases within a networked community by integrating epidemic transmission and public opinion dynamics. We propose a novel discrete-time networked SIS (Susceptible-Infectious-Susceptible)…

Systems and Control · Electrical Eng. & Systems 2025-08-14 Qiulin Xu , Tatsuya Masada , Hideaki Ishii

Using SimPy and Discrete Event Simulation we have observed the different model responses of a system consisting of a hospital and people getting sick/healing under different initial conditions. In our model, each independent person can get…

Numerical Analysis · Mathematics 2022-03-25 Dincer Atasoy

Mathematical modeling of disease outbreaks can infer the future trajectory of an epidemic, which can inform policy decisions. Another task is inferring the origin of a disease, which is relatively difficult with current mathematical models.…

Physics and Society · Physics 2022-08-31 Mehrad Ansari , David Soriano-Paños , Gourab Ghoshal , Andrew D. White

The dynamics of contact networks and epidemics of infectious diseases often occur on comparable time scales. Ignoring one of these time scales may provide an incomplete understanding of the population dynamics of the infection process. We…

Populations and Evolution · Quantitative Biology 2021-02-09 Luis E C Rocha , Naoki Masuda

The abundance of data affords researchers to pursue more powerful computational tools to learn the dynamics of complex system, such as neural networks, engineered systems and social networks. Traditional machine learning approaches capture…

Machine Learning · Computer Science 2024-05-16 Yan Shen , Fan Yang , Mingchen Gao , Wen Dong

The integration of empirical data in computational frameworks to model the spread of infectious diseases poses challenges that are becoming pressing with the increasing availability of high-resolution information on human mobility and…

Populations and Evolution · Quantitative Biology 2013-04-24 Anna Machens , Francesco Gesualdo , Caterina Rizzo , Alberto E Tozzi , Alain Barrat , Ciro Cattuto

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

Machine Learning · Computer Science 2025-10-22 Harry Amad , Zhaozhi Qian , Dennis Frauen , Julianna Piskorz , Stefan Feuerriegel , Mihaela van der Schaar

We propose a deep generative approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories, with a particular focus on Systemic Sclerosis (SSc). We aim to learn temporal latent representations…

This paper presents a novel approach to simulating electronic health records (EHRs) using diffusion probabilistic models (DPMs). Specifically, we demonstrate the effectiveness of DPMs in synthesising longitudinal EHRs that capture…

Machine Learning · Computer Science 2023-03-23 Nicholas I-Hsien Kuo , Louisa Jorm , Sebastiano Barbieri

Access to real-world healthcare data is limited by stringent privacy regulations and data imbalances, hindering advancements in research and clinical applications. Synthetic data presents a promising solution, yet existing methods often…

Machine Learning · Computer Science 2025-03-11 Nicholas I-Hsien Kuo , Blanca Gallego , Louisa Jorm

In this paper, we present a diagnosis method of diseases from clinical data. The data are routine test such as urine test, hematology, chemistries etc. Though those tests have been done for people who check in medical institutes, how each…

Computational Engineering, Finance, and Science · Computer Science 2007-05-23 Gene Kim , MyungHo Kim