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This paper proposes a novel approach of integrating different neuroimaging techniques to characterize an autistic brain. Different techniques like EEG, fMRI and DTI have traditionally been used to find biomarkers for autism, but there have…

Functional connectivity (FC) derived from functional magnetic resonance imaging (fMRI) data offers vital insights for understanding brain function and neurological and psychiatric disorders. Unsupervised clustering methods are desired to…

Methodology · Statistics 2025-12-04 Yixi Xu , Yi Zhao

We propose a novel two-phase approach to functional network estimation of multi-subject functional Magnetic Resonance Imaging (fMRI) data, which applies model-based image segmentation to determine a group-representative connectivity map. In…

Computation · Statistics 2018-09-05 Aditi Iyer , Bingjing Tang , Vinayak Rao , Nan Kong

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Coherence is a widely used measure to assess linear relationships between time series. However, it fails to capture nonlinear dependencies. To overcome this limitation, this paper introduces the notion of residual spectral density as a…

Statistics Theory · Mathematics 2024-05-21 Yuichi Goto , Xuze Zhang , Benjamin Kedem , Shuo Chen

The extraction of brain functioning features is a crucial step in the definition of brain-computer interfaces (BCIs). In the last decade, functional connectivity (FC) estimators have been increasingly explored based on their ability to…

Neurons and Cognition · Quantitative Biology 2019-12-06 Tiziana Cattai , Stefania Colonnese , Marie-Constance Corsi , Danielle S. Bassett , Gaetano Scarano , Fabrizio De Vico Fallani

We propose a statistical learning model for classifying cognitive processes based on distributed patterns of neural activation in the brain, acquired via functional magnetic resonance imaging (fMRI). In the proposed learning method, local…

Artificial Intelligence · Computer Science 2014-03-07 Orhan Firat , Mete Ozay , Ilke Oztekin , Fatos T. Yarman Vural

Detecting and evaluating regions of brain under various circumstances is one of the most interesting topics in computational neuroscience. However, the majority of the studies on detecting communities of a functional connectivity network of…

Social and Information Networks · Computer Science 2018-06-04 Keivan Hassani Monfared , Kris Vasudevan , Jordan S. Farrell , G. Campbell Teskey

We investigate whether and how we can improve the cost efficiency of neuroimaging studies with well-tailored fMRI tasks. The comparative study is conducted using a novel network science-driven Bayesian connectome-based predictive method,…

Applications · Statistics 2024-11-05 Xinzhi Zhang , Leslie A Hulvershorn , Todd Constable , Yize Zhao , Selena Wang

In this paper, we present a novel and versatile method to study the dynamics of resting-state fMRI brain connectivity with a high temporal sensitivity. Whereas most existing methods often rely on dividing the time-series into larger…

Neurons and Cognition · Quantitative Biology 2016-01-14 William Hedley Thompson , Peter Fransson

Objective: New measures of human brain connectivity are needed to address gaps in the existing measures and facilitate the study of brain function, cognitive capacity, and identify early markers of human disease. Traditional approaches to…

Neurons and Cognition · Quantitative Biology 2023-08-28 Cooper J. Mellema , Albert Montillo

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

Current functional Magnetic Resonance Imaging technology is able to resolve billions of individual functional connections characterizing the human connectome. Classical statistical inferential procedures attempting to make valid inferences…

Quantitative Methods · Quantitative Biology 2023-01-11 Alfonso Nieto-Castanon

Most generally, dynamic functional connectivity (FC) refers to the non-instantaneous couplings across timeseries from a set of brain areas, here as measured by fMRI. This is in contrast to static FC, which is defined as purely instantaneous…

Neurons and Cognition · Quantitative Biology 2023-01-10 Christine Ahrends , Diego Vidaurre

Functional magnetic resonance imaging (fMRI) is one of the most popular methods for studying the human brain. Task-related fMRI data processing aims to determine which brain areas are activated when a specific task is performed and is…

Signal Processing · Electrical Eng. & Systems 2022-10-18 Paris A. Karakasis , Athanasios P. Liavas , Nicholas D. Sidiropoulos , Panagiotis G. Simos , Efrosini Papadaki

This paper considers a novel problem, bi-level graphical modeling, in which multiple individual graphical models can be considered as variants of a common group-level graphical model and inference of both the group- and individual-level…

Methodology · Statistics 2021-08-12 Lin Zhang , Andrew DiLernia , Karina Quevedo , Jazmin Camchong , Kelvin Lim , Wei Pan1

In this study we focus on the problem of joint learning of multiple differential networks with function Magnetic Resonance Imaging (fMRI) data sets from multiple research centers. As the research centers may use different scanners and…

Methodology · Statistics 2021-06-08 Hao Chen , Ying Guo , Yong He , Dong Liu , Lei Liu , Xiao-Hua Zhou

Graphical models have been used extensively for modeling brain connectivity networks. However, unmeasured confounders and correlations among measurements are often overlooked during model fitting, which may lead to spurious scientific…

Methodology · Statistics 2020-12-10 Yanxin Jin , Yang Ning , Kean Ming Tan

Dynamic functional connectivity analysis provides valuable information for understanding brain functional activity underlying different cognitive processes. Besides sliding window based approaches, a variety of methods have been developed…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Hongming Li , Yong Fan

This study proposes an approach to estimate the functional localization and connectivity from CBF and BOLD signals simultaneously measured by ASL (arterial spin labeling) MRI, especially using exploratory Structural Equation Modeling…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jiancheng Zhuang