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Related papers: On the Swimming of \textit{Dictyostelium} amoebae

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Recent experimental work has shown that eukaryotic cells can swim in a fluid as well as crawl on a substrate. We investigate the swimming behavior of Dictyostelium discoideum amoebae who swim by initiating traveling protrusions at the front…

Cell Behavior · Quantitative Biology 2015-09-14 Qixuan Wang , Hans G. Othmer

Cells and microorganisms adopt various strategies to migrate in response to different environmental stimuli. To date, many modeling research has focused on the crawling-based Dictyostelium discoideum (Dd) cells migration induced by…

Tissues and Organs · Quantitative Biology 2021-04-20 Qixuan Wang , Hao Wu

Several micro-organisms, such as bacteria, algae, or spermatozoa, use flagella or cilia to swim in a fluid, while many other micro-organisms instead use ample shape deformation, described as amoeboid, to propel themselves by either crawling…

Biological Physics · Physics 2016-09-19 Hao Wu , A. Farutin , W. -F. Hu , M. Thiébaud , S. Rafaï , P. Peyla , M. -C. Lai , C. Misbah

The behaviour of an organism often reflects a strategy for coping with its environment. Such behaviour in higher organisms can often be reduced to a few stereotyped modes of movement due to physiological limitations, but finding such modes…

Cell Behavior · Quantitative Biology 2013-08-26 Luke Tweedy , Börn Meier , Jürgen Stephan , Doris Heinrich , Robert G. Endres

Morphologies of moving amoebae are categorized into two types. One is the ``neutrophil'' type in which the long axis of cell roughly coincides with its moving direction. This type of cell extends a leading edge at the front and retracts a…

Cell Behavior · Quantitative Biology 2007-05-23 Shin I. Nishimura , Masaki Sasai

Many eukaryotic cells undergo frequent shape changes (described as amoeboid motion) that enable them to move forward. We investigate the effect of confinement on a minimal model of amoeboid swimmer. Complex pictures emerge: (i) The…

Biological Physics · Physics 2015-11-11 Hao Wu , M. Thiébaud , W. -F. Hu , A. Farutin , S. Rafaï , M. -C. Lai , P. Peyla , C. Misbah

The motility of adherent eukaryotic cells is driven by the dynamics of the actin cytoskeleton. Despite the common force-generating actin machinery, different cell types often show diverse modes of locomotion that differ in their shape…

Biological Physics · Physics 2022-07-15 T. Moldenhawer , E. Moreno , D. Schindler , S. Flemming , M. Holschneider , W. Huisinga , S. Alonso , C. Beta

Eukaryotic cell motility involves a complex network of interactions between biochemical components and mechanical processes. The cell employs this network to polarize and induce shape changes that give rise to membrane protrusions and…

Cell Behavior · Quantitative Biology 2022-01-03 E. Moreno , S. Flemming , F. Font , M. Holschneider , C. Beta , S. Alonso

There is increasing evidence that mammalian cells not only crawl on substrates but can also swim in fluids. To elucidate the mechanisms of the onset of motility of cells in suspension, a model which couples actin and myosin kinetics to…

Biological Physics · Physics 2019-09-18 Alexander Farutin , Jocelyn Etienne , Chaouqi Misbah , Pierre Recho

The coupling of the internal mechanisms of cell polarization to cell shape deformations and subsequent cell crawling poses many interdisciplinary scientific challenges. Several mathematical approaches have been proposed to model the…

Cell Behavior · Quantitative Biology 2023-11-08 Eduardo Moreno , Robert Großmann , Carsten Beta , Sergio Alonso

One of the essential functions of living organisms is spontaneous migration through the deformation of their body, such as crawling, swimming, and walking. Depending on the size of the object, the efficient migratory mode should be altered…

Soft Condensed Matter · Physics 2024-02-07 H. Ebata , Y. Nishigami , H. Fujiwara , S. Kidoaki , M. Ichikawa

Amoeboid motion is a dynamic mode of cell motility essential for processes such as the immune response and wound healing. This review examines recent developments in the mathematical and computational modeling of amoeboid crawling, focusing…

Biological Physics · Physics 2026-03-17 Sergio Alonso , Carsten Beta

Eukaryotic swimming cells such as spermatozoa, algae or protozoa use flagella or cilia to move in viscous fluids. The motion of their flexible appendages in the surrounding fluid induces propulsive forces that balance with the viscous drag…

Soft Condensed Matter · Physics 2023-10-06 Maciej Lisicki , Marcos F. Velho Rodrigues , Eric Lauga

Quantitative experiments are described on spatio-temporal patterns of coherent chemical signaling activity in populations of {\it Dictyostelium discoideum} amoebae. We observe competition between spontaneously firing centers and rotating…

Condensed Matter · Physics 2009-10-28 Kyoung J. Lee , Edward C. Cox , Raymond E. Goldstein

Eukaryotic cell motility is crucial during development, wound healing, the immune response, and cancer metastasis. Some eukaryotic cells can swim, but cells more commonly adhere to and crawl along the extracellular matrix. We study the…

Cell Behavior · Quantitative Biology 2019-09-02 Melissa H. Mai , Brian A. Camley

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

Biological Physics · Physics 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

Unicellular microscopic organisms living in aqueous environments outnumber all other creatures on Earth. A large proportion of them are able to self-propel in fluids with a vast diversity of swimming gaits and motility patterns. In this…

Biological Physics · Physics 2021-07-14 Marcos F. Velho Rodrigues , Maciej Lisicki , Eric Lauga

Eukaryotic cells are large enough to detect signals and then orient to them by differentiating the signal strength across the length and breadth of the cell. Amoebae, fibroblasts, neutrophils and growth cones all behave in this way. Little…

Cell Behavior · Quantitative Biology 2008-05-19 Liang Li , Simon F. Norrelykke , Edward C. Cox

The propulsion of mammalian spermatozoa relies on the spontaneous periodic oscillation of their flagella. These oscillations are driven internally by the coordinated action of ATP-powered dynein motors that exert sliding forces between…

Fluid Dynamics · Physics 2022-10-13 Chenji Li , Brato Chakrabarti , Pedro Castilla , Achal Mahajan , David Saintillan

Bacterial swimming is well characterized in uniform liquids at rest. The natural habitat of bacterial swimmers, however, is often dominated by moving fluids and interfaces, resulting in shear flows that may strongly alter bacterial…

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