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A fundamental problem in neuroscience is to characterize the dynamics of spiking from the neurons in a circuit that is involved in learning about a stimulus or a contingency. A key limitation of current methods to analyze neural spiking…

Methodology · Statistics 2017-09-29 Yingzhuo Zhang , Noa Malem-Shinitski , Stephen A Allsop , Kay Tye , Demba Ba

Hippocampal neurons exhibit precise phase locking to network oscillations, but the computational principle governing this temporal precision is still unclear. Neural information is conveyed jointly by firing rates and spike timing, but…

Neurons and Cognition · Quantitative Biology 2026-03-23 Reza Ahmadvand , Sara Safura Sharif , Yaser Mike Banad

The characterization of network and biophysical properties from neural spiking activity is an important goal in neuroscience. A framework that provides unbiased inference on causal synaptic interaction and single neural properties has been…

Neurons and Cognition · Quantitative Biology 2024-05-27 Kevin S. Chen , Ying-Jen Yang

We present the mathematical basis of a new approach to the analysis of temporal coding. The foundation of the approach is the construction of several families of novel distances (metrics) between neuronal impulse trains. In contrast to most…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jonathan D. Victor , Keith P. Purpura

We present a theoretical application of an optimal experiment design (OED) methodology to the development of mathematical models to describe the stimulus-response relationship of sensory neurons. Although there are a few related studies in…

Neurons and Cognition · Quantitative Biology 2016-10-19 R. Ozgur Doruk , Kechen Zhang

Spiking Neural Networks (SNNs) operate with asynchronous discrete events (or spikes) which can potentially lead to higher energy-efficiency in neuromorphic hardware implementations. Many works have shown that an SNN for inference can be…

Machine Learning · Computer Science 2020-05-06 Nitin Rathi , Gopalakrishnan Srinivasan , Priyadarshini Panda , Kaushik Roy

Neuromorphic computing targets energy-efficient event-driven information processing by placing artificial spiking-neurons at its core. Artificial neuron devices and circuits have multiple operating modes and produce region-dependent…

Applied Physics · Physics 2026-01-06 Zhiwei Li , Shi-Li Zhang , Chenyu Wen

The combination of new recording techniques in neuroscience and powerful inference methods recently held the promise to recover useful effective models, at the single neuron or network level, directly from observed data. The value of a…

Neurons and Cognition · Quantitative Biology 2018-04-09 Cristiano Capone , Guido Gigante , Paolo Del Giudice

Accurate performance estimation of future many-node machines is challenging because it requires detailed simulation models of both node and network. However, simulating the full system in detail is unfeasible in terms of compute and memory…

Performance · Computer Science 2024-01-19 Stijn Eyerman , Wim Heirman , Kristof Du Bois , Ibrahim Hur

In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…

Neurons and Cognition · Quantitative Biology 2026-05-01 Terrence J. Sejnowski

In this article, we review a class of neuro-mimetic computational models that we place under the label of spiking predictive coding. Specifically, we review the general framework of predictive processing in the context of neurons that emit…

Neurons and Cognition · Quantitative Biology 2024-09-10 Antony W. N'dri , William Gebhardt , Céline Teulière , Fleur Zeldenrust , Rajesh P. N. Rao , Jochen Triesch , Alexander Ororbia

The computational inefficiency of spiking neural networks (SNNs) is primarily due to the sequential updates of membrane potential, which becomes more pronounced during extended encoding periods compared to artificial neural networks (ANNs).…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Hanqi Chen , Lixing Yu , Shaojie Zhan , Penghui Yao , Jiankun Shao

Many recently introduced enhanced sampling techniques are based on biasing coarse descriptors (collective variables) of a molecular system on the fly. Sometimes the calculation of such collective variables is expensive and becomes a…

Computational Physics · Physics 2015-09-01 Marco Jacopo Ferrarotti , Sandro Bottaro , Andrea Pérez-Villa , Giovanni Bussi

We present two Bayesian procedures to infer the interactions and external currents in an assembly of stochastic integrate-and-fire neurons from the recording of their spiking activity. The first procedure is based on the exact calculation…

Machine Learning · Statistics 2011-02-28 Remi Monasson , Simona Cocco

Diabetes mellitus affects over 537 million adults worldwide. Insulin-dependent patients require continuous glucose monitoring and precise dose calculation while operating under strict power budgets on wearable devices. This paper presents…

Machine Learning · Computer Science 2026-03-31 Sahil Shrivastava

Spiking neural networks (SNNs) promise energy-efficient computation by mimicking biological neural dynamics, yet existing plasticity rules focus on isolated spike pairs and fail to leverage the synchronous activity patterns that drive…

Neural and Evolutionary Computing · Computer Science 2025-08-26 Yuchen Tian , Assel Kembay , Samuel Tensingh , Nhan Duy Truong , Jason K. Eshraghian , Omid Kavehei

To understand possible strategies of temporal spike coding in the central nervous system, we study functional neuromimetic models of visual processing for static images. We will first present the retinal model which was introduced by Van…

Neurons and Cognition · Quantitative Biology 2007-05-23 Laurent Perrinet , Manuel Samuelides , Simon Thorpe

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

Statistics Theory · Mathematics 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

Traditional neuron models use analog values for information representation and computation, while all-or-nothing spikes are employed in the spiking ones. With a more brain-like processing paradigm, spiking neurons are more promising for…

Neural and Evolutionary Computing · Computer Science 2021-02-05 Qiang Yu , Shiming Song , Chenxiang Ma , Linqiang Pan , Kay Chen Tan

Artificial spiking neural networks have found applications in areas where the temporal nature of activation offers an advantage, such as time series prediction and signal processing. To improve their efficiency, spiking architectures often…

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