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We analyze transport on a graph with multiple constraints and where the weight of the edges connecting the nodes is a dynamical variable. The network dynamics results from the interplay between a nonlinear function of the flow, dissipation,…

Statistical Mechanics · Physics 2023-11-28 Frederic Folz , Kurt Mehlhorn , Giovanna Morigi

The response to a knockout of a node is a characteristic feature of a networked dynamical system. Knockout resilience in the dynamics of the remaining nodes is a sign of robustness. Here we study the effect of knockouts for binary state…

Molecular Networks · Quantitative Biology 2013-05-29 Gunnar Boldhaus , Nils Bertschinger , Johannes Rauh , Eckehard Olbrich , Konstantin Klemm

Strong resilience properties of dynamical flow networks are analyzed for distributed routing policies. The latter are characterized by the property that the way the inflow at a non-destination node gets split among its outgoing links is…

Systems and Control · Computer Science 2011-03-28 Giacomo Como , Ketan Savla , Daron Acemoglu , Munther A. Dahleh , Emilio Frazzoli

Boolean networks have been used in a variety of settings, as models for general complex systems as well as models of specific systems in diverse fields, such as biology, engineering, and computer science. Traditionally, their properties as…

Dynamical Systems · Mathematics 2024-02-02 Matthew Wheeler , Claus Kadelka , Alan Veliz-Cuba , David Murrugarra , Reinhard Laubenbacher

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

In automata networks, it is well known that the way entities update their states over time has a major impact on their dynamics. In particular, depending on the chosen update schedule, the underlying dynamical systems may exhibit more or…

Discrete Mathematics · Computer Science 2022-04-25 Jacques Demongeot , Sylvain Sené

Stochastic network design is a general framework for optimizing network connectivity. It has several applications in computational sustainability including spatial conservation planning, pre-disaster network preparation, and river network…

Artificial Intelligence · Computer Science 2016-12-02 Xiaojian Wu , Akshat Kumar , Daniel Sheldon , Shlomo Zilberstein

Many biological systems, such as metabolic pathways, exhibit bistability behavior: these biological systems exhibit two distinct stable states with switching between the two stable states controlled by certain conditions. Since…

Quantitative Methods · Quantitative Biology 2013-07-04 Yi Ming Zou

An observability condition number is defined for physical systems modeled by network dynamics. Assuming the dynamical equations of the network are known and a noisy trajectory is observed at a subset of the nodes, we calculate the expected…

Dynamical Systems · Mathematics 2018-09-12 Jiajing Guan , Tyrus Berry , Timothy Sauer

We present a rigorous mathematical framework for analyzing dynamics of a broad class of Boolean network models. We use this framework to provide the first formal proof of many of the standard critical transition results in Boolean network…

Disordered Systems and Neural Networks · Physics 2016-08-30 C. Seshadhri , Yevgeniy Vorobeychik , Jackson R. Mayo , Robert C. Armstrong , Joseph R. Ruthruff

We study the problem of computing a minimal subset of nodes of a given asynchronous Boolean network that need to be controlled to drive its dynamics from an initial steady state (or attractor) to a target steady state. Due to the phenomenon…

Systems and Control · Computer Science 2018-05-18 Soumya Paul , Cui Su , Jun Pang , Andrzej Mizera

Effective control of biological systems can often be achieved through the control of a surprisingly small number of distinct variables. We bring clarity to such results using the formalism of Boolean dynamical networks, analyzing the…

Molecular Networks · Quantitative Biology 2021-09-13 Enrico Borriello , Bryan C. Daniels

Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

Molecular Networks · Quantitative Biology 2023-02-06 Larry Bull

The complex dynamics of gene expression in living cells can be well-approximated using Boolean networks. The average sensitivity is a natural measure of stability in these systems: values below one indicate typically stable dynamics…

Molecular Networks · Quantitative Biology 2018-10-03 Bryan C. Daniels , Hyunju Kim , Douglas Moore , Siyu Zhou , Harrison Smith , Bradley Karas , Stuart A. Kauffman , Sara I. Walker

Now that Bayesian Networks (BNs) have become widely used, an appreciation is developing of just how critical an awareness of the sensitivity and robustness of certain target variables are to changes in the model. When time resources are…

Methodology · Statistics 2018-11-20 Sophia K. Wright , Jim Q. Smith

The study of the interplay between the structure and dynamics of complex multilevel systems is a pressing challenge nowadays. In this paper, we use a semi-annealed approximation to study the stability properties of Random Boolean Networks…

Physics and Society · Physics 2012-10-31 Emanuele Cozzo , Alex Arenas , Yamir Moreno

Dynamical systems theory and complexity science provide powerful tools for analysing artificial agents and robots. Furthermore, they have been recently proposed also as a source of design principles and guidelines. Boolean networks are a…

Artificial Intelligence · Computer Science 2015-03-18 Andrea Roli , Mattia Manfroni , Carlo Pinciroli , Mauro Birattari

Random Boolean networks, originally invented as models of genetic regulatory networks, are simple models for a broad class of complex systems that show rich dynamical structures. From a biological perspective, the most interesting networks…

Disordered Systems and Neural Networks · Physics 2009-11-07 Joshua E. S. Socolar , Stuart A. Kauffman

We study a genetic regulatory network model developed to demonstrate that genetic robustness can evolve through stabilizing selection for optimal phenotypes. We report preliminary results on whether such selection could result in a…

Molecular Networks · Quantitative Biology 2010-12-07 Volkan Sevim , Per Arne Rikvold

This paper studies the observability radius of network systems, which measures the robustness of a network to perturbations of the edges. We consider linear networks, where the dynamics are described by a weighted adjacency matrix, and…

Systems and Control · Computer Science 2016-12-20 Gianluca Bianchin , Paolo Frasca , Andrea Gasparri , Fabio Pasqualetti
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