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The design of biological networks using bacteria as the basic elements of the network is initially motivated by a phenomenon called quorum sensing. Through quorum sensing, each bacterium performs sensing the medium and communicating it to…

Information Theory · Computer Science 2012-05-23 Arash Einolghozati , Mohsen Sardari , Faramarz Fekri

Nonlinear coupling between inter- and intra-element dynamics appears as a collective behaviour of elements. The elements in this paper denote symptoms such as a bacterium having an internal network of genes and proteins, a reactive droplet,…

Physics and Society · Physics 2013-05-29 Dan Tanaka

Building oscillator based computing systems with emerging nano-device technologies has become a promising solution for unconventional computing tasks like computer vision and pattern recognition. However, simulation and analysis of these…

Emerging Technologies · Computer Science 2016-11-15 Yan Fang , Victor V. Yashin , Donald M. Chiarulli , Steven P. Levitan

The study of synchronization among genetic oscillators is essential for the understanding of the rhythmic phenomena of living organisms at both molecular and cellular levels. Genetic networks are intrinsically noisy due to natural random…

Molecular Networks · Quantitative Biology 2007-05-23 Chunguang Li , Luonan Chen , Kazuyuki Aihara

In the first part of this paper, we showed that three coupled populations of identical phase oscillators give rise to heteroclinic cycles between invariant sets where populations show distinct frequencies. Here, we now give explicit…

Dynamical Systems · Mathematics 2019-08-05 Christian Bick , Alexander Lohse

Interacting populations often create complicated spatiotemporal behavior, and understanding it is a basic problem in the dynamics of spatial systems. We study the two-species case by simulations of a host--parasitoid model. In the case of…

Populations and Evolution · Quantitative Biology 2009-01-16 Matti Peltomaki , Martin Rost , Mikko Alava

The control of network-coupled nonlinear dynamical systems is an active area of research in the nonlinear science community. Coupled oscillator networks represent a particularly important family of nonlinear systems, with applications…

Adaptation and Self-Organizing Systems · Physics 2016-08-03 Per Sebastian Skardal , Alex Arenas

Numerous biological systems exhibit transitions to synchronised oscillations via a population-density-dependant mechanism known as quorum sensing. Here we propose a model system, based on spatially distributed limit-cycle oscillators, that…

Analysis of PDEs · Mathematics 2022-08-22 Carles Tardío Pi , Jorge Castillo Medina , Pablo Padilla Longoria

Oscillatory behavior is ubiquitous in many natural and engineered systems, often emerging through self-regulating mechanisms. In this paper, we address the challenge of stabilizing a desired oscillatory pattern in a networked system where…

Systems and Control · Electrical Eng. & Systems 2025-02-05 Luis Guillermo Venegas-Pineda , Hildeberto Jardón-Kojakhmetov , Ming Cao

A model of clustering dynamics is proposed for a population of spatially distributed active rotators. A transition from excitable to oscillatory dynamics is induced by the increase of the local density of active rotators. It is interpreted…

Pattern Formation and Solitons · Physics 2015-06-12 Hidetsugu Sakaguchi , Satomi Maeyama

Many physical, chemical and biological systems can be modeled by means of random-frequency harmonic oscillator systems. Even though the noise-free evolution of harmonic oscillator systems can be easily implemented, the way to experimentally…

Classical Physics · Physics 2014-07-11 R. de J. León-Montiel , J. Svozilík , Juan P. Torres

The emergence of synchronization in a network of coupled oscillators is a pervasive topic in various scientific disciplines ranging from biology, physics, and chemistry to social networks and engineering applications. A coupled oscillator…

Optimization and Control · Mathematics 2012-09-07 Florian Dörfler , Francesco Bullo

The study of synchronization in populations of coupled biological oscillators is fundamental to many areas of biology to include neuroscience, cardiac dynamics and circadian rhythms. Studying these systems may involve tracking the…

Quantitative Methods · Quantitative Biology 2017-01-18 Kevin M. Hannay , Daniel B. Forger , Victoria Booth

In many natural synchronization phenomena, communication between individual elements occurs not directly, but rather through the environment. One of these instances is bacterial quorum sensing, where bacteria release signaling molecules in…

Dynamical Systems · Mathematics 2015-05-18 Giovanni Russo , Jean-Jacques E. Slotine

Microbes are everywhere, including in and on our bodies, and have been shown to play key roles in a variety of prevalent human diseases. Consequently, there has been intense interest in the design of bacteriotherapies or "bugs as drugs,"…

Machine Learning · Statistics 2020-04-13 Travis E. Gibson , Georg K. Gerber

An important design principle for biological oscillators divides the oscillators into two classes: fixed frequency, variable amplitude and fixed amplitude, variable frequency. Because of the interplay of nonlinearity and feedback, both…

Systems and Control · Electrical Eng. & Systems 2026-04-14 Sidhanta Mohanty , Shaunak Sen

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

Statistical Mechanics · Physics 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

In this paper, experimental data is presented and a simple model is developed for the time evolution of a F-amp \textit{E. Coli} culture population. In general, the bacteria life cycle as revealed by monitoring a culture's population…

Populations and Evolution · Quantitative Biology 2019-12-19 Atanu Chatterjee , Nicholas Mears , Abigail Charest , Saad Algarni , Germano Iannnacchione

Genetic circuit design is a well-studied problem in synthetic biology. Ever since the first genetic circuits -- the repressilator and the toggle switch -- were designed and implemented, many advances have been made in this area of research.…

Molecular Networks · Quantitative Biology 2021-11-09 Debomita Chakraborty , Raghunathan Rengaswamy , Karthik Raman

The collective behavior of biological oscillators has been recognized as an important problem for several decades, but its control has come into limelight only recently. Much of the focus for control has been on desynchronization of an…

Adaptation and Self-Organizing Systems · Physics 2019-07-09 Bharat Monga , Jeff Moehlis