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In conflict with standard notions of thermodynamics, mesoscopically-sized inclusions (``clusters'') of a solute-rich liquid have been observed in equilibrated solutions of proteins and other molecules. According to a complexation scenario…

Soft Condensed Matter · Physics 2025-09-11 Ilya Davydov , Vassiliy Lubchenko

We present a novel framework exploiting the cascade of phase transitions occurring during a simulated annealing of the Expectation-Maximisation algorithm to cluster datasets with multi-scale structures. Using the weighted local covariance,…

Machine Learning · Statistics 2021-01-13 T. Bonnaire , A. Decelle , N. Aghanim

We describe a simulation method for the accurate study of the equilibrium freezing properties of polydisperse fluids under the experimentally relevant condition of fixed polydispersity. The approach is based on the phase switch Monte Carlo…

Soft Condensed Matter · Physics 2009-11-13 Nigel B. Wilding

Importance sampling is a Monte Carlo technique for efficiently estimating the likelihood of rare events by biasing the sampling distribution towards the rare event of interest. By drawing weighted samples from a learned proposal…

Machine Learning · Statistics 2025-05-20 Liam A. Kruse , Marc R. Schlichting , Mykel J. Kochenderfer

Kinetic equations model the position-velocity distribution of particles subject to transport and collision effects. Under a diffusive scaling, these combined effects converge to a diffusion equation for the position density in the limit of…

Numerical Analysis · Mathematics 2023-07-26 Emil Løvbak , Giovanni Samaey

Grand canonical Monte Carlo simulations are used to explore the metastable fluid-fluid coexistence curve of the modified Lennard-Jones model of globular proteins of ten Wolde and Frenkel (Science, v277, 1975 (1997)). Using both mixed-field…

Soft Condensed Matter · Physics 2009-11-10 D. L. Pagan , M. E. Gracheva , J. D. Gunton

We have simulated the three-dimensional Heisenberg model on simple cubic lattices, using the single-cluster Monte Carlo update algorithm. The expected pronounced reduction of critical slowing down at the phase transition is verified. This…

High Energy Physics - Lattice · Physics 2009-10-22 Christian Holm , Wolfhard Janke

Monte Carlo simulations are a powerful tool to investigate the thermodynamic properties of atomic systems. In practice however, sampling of the complete configuration space is often hindered by high energy barriers between different regions…

Statistical Mechanics · Physics 2020-05-04 Jonas A. Finkler , Stefan Goedecker

We review the use of the path integral Monte Carlo (PIMC) methodology to the study of finite-size quantum clusters, with particular emphasis on recent applications to pure and impurity-doped He clusters. We describe the principles of PIMC,…

Chemical Physics · Physics 2016-11-23 Patrick Huang , Yongkyung Kwon , K. Birgitta Whaley

Multi-component polymer systems are of interest in organic photovoltaic and drug delivery applications, among others where diverse morphologies influence performance. An improved understanding of morphology classification, driven by…

Computational Engineering, Finance, and Science · Computer Science 2020-08-27 Pavan Inguva , Lachlan Mason , Indranil Pan , Miselle Hengardi , Omar K. Matar

Unitary coupled cluster (UCC), originally developed as a variational alternative to the popular traditional coupled cluster method, has seen a resurgence as a functional form for use on quantum computers. However, the number of excitors…

Chemical Physics · Physics 2021-01-07 Maria-Andreea Filip , Alex J. W. Thom

A method for selecting events with densely populated narrow regions or spikes in a given data sample is discussed. Applying this method to 200 A GeV/c 32S-AgBr and 32S-Gold collision data, a few events having "hot regions" are chosen for…

Nuclear Experiment · Physics 2015-10-13 Shakeel Ahmad , M. M. Khan , Shaista Khan , A. Khatun , M. Irfan

We study the size of clusters formed by water molecules possessing large enough tetrahedrality with respect to their nearest neighbors. Using Monte Carlo simulation of the SPC/E model of water, together with a geometric analysis based on…

Statistical Mechanics · Physics 2009-11-07 Jeffrey R. Errington , Pablo G. Debenedetti , Salvatore Torquato

Determining the number of clusters is a fundamental issue in data clustering. Several algorithms have been proposed, including centroid-based algorithms using the Euclidean distance and model-based algorithms using a mixture of probability…

Machine Learning · Computer Science 2024-07-30 Ryosuke Motegi , Yoichi Seki

A mixture of joint generalized hyperbolic distributions (MJGHD) is introduced for asymmetric clustering for high-dimensional data. The MJGHD approach takes into account the cluster-specific subspace, thereby limiting the number of…

Methodology · Statistics 2018-11-02 Yang Tang , Ryan P. Browne , Paul D. McNicholas

We consider the question of Markov chain Monte Carlo sampling from a general stick-breaking Dirichlet process mixture model, with concentration parameter alpha. This paper introduces a Gibbs sampling algorithm that combines the slice…

Computation · Statistics 2014-02-21 David I. Hastie , Silvia Liverani , Sylvia Richardson

Fluids made of two-dimensional hard particles with polygonal shapes may stabilize symmetries which do not result directly from the particle shape. This is due to the formation of clusters in the fluid. Entropy alone can drive these effects,…

Soft Condensed Matter · Physics 2024-02-05 Yuri Martinez-Raton , Enrique Velasco

Metropolis Monte Carlo simulation is a powerful tool for studying the equilibrium properties of matter. In complex condensed-phase systems, however, it is difficult to design Monte Carlo moves with high acceptance probabilities that also…

Statistical Mechanics · Physics 2014-05-27 Jerome P. Nilmeier , Gavin E. Crooks , David D. L. Minh , John D. Chodera

A recent reformulation [1] of the problem of Coulomb gases in the presence of a dynamical dielectric medium showed that finite temperature simulations of such systems can be accomplished on the basis of completely local Hamiltonians on a…

Soft Condensed Matter · Physics 2009-11-11 A. Duncan , R. D. Sedgewick

We present a single-particle Lennard-Jones (L-J) model for CO2 and N2. Simplified L-J models for other small polyatomic molecules can be obtained following the methodology described herein. The phase-coexistence diagrams of single-component…

Computational Physics · Physics 2015-06-11 Jun Li , Victor M. Calo
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