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We present a thorough analysis of single atom detection using optical cavities. The large set of parameters that influence the signal-to-noise ratio for cavity detection is considered, with an emphasis on detunings, probe power, cavity…

Quantum Physics · Physics 2008-08-07 R. Poldy , B. C. Buchler , J. C. Close

High-throughput label-free measurements of the optical and mechanical properties of single microparticles play an important role in biological research, drug development, and related large population assays. Mechanical detection techniques…

Instrumentation and Detectors · Physics 2018-12-05 Kewen Han , Jeewon Suh , Gaurav Bahl

Single photon detectors are indispensable tools in optics, from fundamental measurements to quantum information processing. The ability of superconducting nanowire single photon detectors to detect single photons with unprecedented…

Optically active quantum dots, for instance self-assembled InGaAs quantum dots, are potentially excellent single photon sources. The fidelity of the single photons is much improved using resonant rather than non-resonant excitation. With…

Mesoscale and Nanoscale Physics · Physics 2014-10-08 Andreas V. Kuhlmann , Julien Houel , Daniel Brunner , Arne Ludwig , Dirk Reuter , Andreas D. Wieck , Richard J. Warburton

Non-invasive light scattering methods provide data on biological macromolecules (i.e. proteins, nucleic acids, as well as assemblies and larger entities composed of them) that are complementary with those of size exclusion chromatography,…

Biomolecules · Quantitative Biology 2018-10-02 Bernard Lorber

Conventional absorption spectroscopy relies on coherent laser sources, and in turn suffers from the inherent limitation of shot noise, especially in estimating weak absorption. Here we propose a measurement strategy with correlated photons…

Quantum Physics · Physics 2025-04-17 Zhucheng Zhang , Xue Zhang , Jing Liu , Hui Dong

In the last years, it was demonstrated that neutral molecules can be loaded on a microchip directly from a supersonic beam. The molecules are confined in microscopic traps that can be moved smoothly over the surface of the chip. Once the…

Atomic Physics · Physics 2015-09-15 Gabriele Santambrogio

Determination of optical absorption cross-section is always among the central importance of understanding a material. However its realization on individual nanostructures, such as carbon nanotubes, is experimentally challenging due to the…

Biological molecules, like all active matter, use free energy to generate force and motion which drive them out of thermal equilibrium, and undergo inherent dynamic interconversion between metastable free energy states separated by levels…

Biological Physics · Physics 2025-08-28 Mark C Leake

Sensors that are able to detect and track single unlabelled biomolecules are an important tool both to understand biomolecular dynamics and interactions at nanoscale, and for medical diagnostics operating at their ultimate detection limits.…

Optics · Physics 2016-11-15 N. P. Mauranyapin , L. S. Madsen , M. A. Taylor , M. Waleed , W. P. Bowen

We present a method for the measurement of small optical absorption coefficients. The method exploits the deformation of cavity Airy peaks that occur if the cavity contains an absorbing material with a non-zero thermo-refractive coefficient…

Accurate knowledge of absorption coefficient of a sample is a prerequisite for measuring the third order optical nonlinearity of materials, which can be a serious limitation for unknown samples. We introduce a method, which measures both…

Optics · Physics 2007-05-23 A. Sharan , S. Abbas Hosseini , D. Goswami

In Nature Photonics 5, 166 (2011), we reported on a planar dielectric antenna that achieved 96% efficiency in collecting the photons emitted by a single molecule. In that work the transition dipole moment of the molecule was set…

Quantum Physics · Physics 2016-04-13 Xue-Wen Chen , Stephan Goetzinger , Vahid Sandoghdar

We introduce an absorption imaging technique for ultracold gases that suppresses interference fringes and coherence-induced artifacts by reducing the transverse spatial coherence of the imaging light. The method preserves the narrow…

Quantum Gases · Physics 2026-02-16 Julia Fekete , Poppy Joshi , Peter Krüger , Fedja Oručević

Spectroscopy is an important tool for probing the properties of materials, chemicals and biological samples. We design a practical transmitter-receiver system that exploits entanglement to achieve a provable quantum advantage over all…

Quantum Physics · Physics 2020-11-03 Haowei Shi , Zheshen Zhang , Stefano Pirandola , Quntao Zhuang

The orientation of luminescent molecules in organic light-emitting diodes (OLEDs) strongly influences device performance. However, our understanding of the factors controlling emitter orientation is limited as current measurements only…

Optical spectroscopy of molecular radicals is an important tool in physical chemistry, and is a prerequisite for many experiments which use molecules for quantum science and precision measurement. However, even the simplest molecules have…

Chemical Physics · Physics 2025-05-07 Ashay N. Patel , Madison I. Howard , Timothy C. Steimle , Nicholas R. Hutzler

We present a new scheme for performing optical spectroscopy on single molecules. A glass capillary with a diameter of 600 nm filled with an organic crystal tightly guides the excitation light and provides a maximum spontaneous emission…

We investigate the optical detection of single atoms held in a microscopic atom trap close to a surface. Laser light is guided by optical fibers or optical micro-structures via the atom to a photo-detector. Our results suggest that with…

An appealing definition of the term "molecule" arises from consideration of the nature of fluorescence, with discrete molecular entities emitting a stream of single photons. We address the question of how large a molecular object may become…

Chemical Physics · Physics 2016-12-12 Thomas Stangl , Philipp Wilhelm , Klaas Remmerssen , Sigurd Hoeger , Jan Vogelsang , John M. Lupton