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In this work, several random Boolean networks (RBN) are generated and analyzed from two characteristics: their time evolution diagram and their transition diagram. For this purpose, its randomness is estimated using three measures, of which…

Information Theory · Computer Science 2024-09-04 Manuel de J. Luevano , Alejandro Puga

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

Molecular Networks · Quantitative Biology 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

We analyze the synchronization transition for a pair of coupled identical Kauffman networks in the chaotic phase. The annealed model for Kauffman networks shows that synchronization appears through a transcritical bifurcation, and provides…

Adaptation and Self-Organizing Systems · Physics 2009-10-31 Luis G. Morelli , Damian H. Zanette

We study two measures of the complexity of heterogeneous extended systems, taking random Boolean networks as prototypical cases. A measure defined by Shalizi et al. for cellular automata, based on a criterion for optimal statistical…

Cellular Automata and Lattice Gases · Physics 2012-06-12 Xinwei Gong , Joshua E. S. Socolar

This review explains in a self-contained way the properties of random Boolean networks and their attractors, with a special focus on critical networks. Using small example networks, analytical calculations, phenomenological arguments, and…

Statistical Mechanics · Physics 2008-11-14 Barbara Drossel

Inferring dynamic biochemical networks is one of the main challenges in systems biology. Given experimental data, the objective is to identify the rules of interaction among the different entities of the network. However, the number of…

Commutative Algebra · Mathematics 2012-07-31 Franziska Hinkelmann , Abdul Salam Jarrah

The dynamics of Boolean networks (the N-K model) with scale-free topology are studied here. The existence of a phase transition governed by the value of the scale-free exponent of the network is shown analytically by analyzing the overlap…

Disordered Systems and Neural Networks · Physics 2007-05-23 Maximino Aldana

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. The topologies of random Boolean networks with one input per…

Disordered Systems and Neural Networks · Physics 2009-11-11 Björn Samuelsson , Carl Troein

Understanding design principles of molecular interaction networks is an important goal of molecular systems biology. Some insights have been gained into features of their network topology through the discovery of graph theoretic patterns…

Molecular Networks · Quantitative Biology 2013-01-18 David Murrugarra , Reinhard Laubenbacher

During the last few years an area of active research in the field of complex systems is that of their information storing and processing abilities. Common opinion has it that the most interesting beaviour of these systems is found ``at the…

adap-org · Physics 2007-05-23 Bartolo Luque , Antonio Ferrera

We investigate analytically and numerically the critical line in undirected random Boolean networks with arbitrary degree distributions, including scale-free topology of connections $P(k)\sim k^{-\gamma}$. We show that in infinite…

Disordered Systems and Neural Networks · Physics 2013-05-29 Piotr Fronczak , Agata Fronczak , Janusz A. Holyst

This paper studies the mathematical properties of collectively canalizing Boolean functions, a class of functions that has arisen from applications in systems biology. Boolean networks are an increasingly popular modeling framework for…

Discrete Mathematics · Computer Science 2023-06-07 Claus Kadelka , Benjamin Keilty , Reinhard Laubenbacher

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

Molecular Networks · Quantitative Biology 2024-02-16 Claus Kadelka , David Murrugarra

Identifying features of molecular regulatory networks is an important problem in systems biology. It has been shown that the combinatorial logic of such networks can be captured in many cases by special functions called nested canalyzing in…

Algebraic Geometry · Mathematics 2013-01-18 David Murrugarra , Reinhard Laubenbacher

We investigate numerically and analytically the formation of the frozen core in critical random Boolean networks with biased functions. We demonstrate that a previously used efficient algorithm for obtaining the frozen core, which starts…

Molecular Networks · Quantitative Biology 2013-02-14 Marco Möller , Barbara Drossel

Canalizing functions have important applications in physics and biology. For example, they represent a mechanism capable of stabilizing chaotic behavior in Boolean network models of discrete dynamical systems. When comparing the class of…

Mathematical Physics · Physics 2009-11-10 Winfried Just , Ilya Shmulevich , John Konvalina

Boolean networks, widely used to model gene regulation, exhibit a phase transition between regimes in which small perturbations either die out or grow exponentially. We show and numerically verify that this phase transition in the dynamics…

Statistical Mechanics · Physics 2013-05-30 Shane Squires , Edward Ott , Michelle Girvan

In a series of articles published in 1986 Derrida, and his colleagues studied two mean field treatments (the quenched and the annealed) for \textit{NK}-Kauffman Networks. Their main results lead to a phase transition curve $ K_c \, 2 \, p_c…

Cellular Automata and Lattice Gases · Physics 2014-04-15 Federico Zertuche

For years, we have been building models of gene regulatory networks, where recent advances in molecular biology shed some light on new structural and dynamical properties of such highly complex systems. In this work, we propose a novel…

Adaptation and Self-Organizing Systems · Physics 2009-09-30 Christian Darabos , Marco Tomassini , Mario Giacobini

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Dynamical Systems · Mathematics 2015-02-26 Marco Villani , Davide Campioli , Chiara Damiani , Andrea Roli , Alessandro Filisetti , Roberto Serra