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There is increasing realization in neuroscience that information is represented in the brain, e.g., neocortex, hippocampus, in the form sparse distributed codes (SDCs), a kind of cell assembly. Two essential questions are: a) how are such…

Machine Learning · Computer Science 2020-10-22 Rod Rinkus

Neural populations encode information about their stimulus in a collective fashion, by joint activity patterns of spiking and silence. A full account of this mapping from stimulus to neural activity is given by the conditional probability…

Neurons and Cognition · Quantitative Biology 2013-06-14 Einat Granot-Atedgi , Gašper Tkačik , Ronen Segev , Elad Schneidman

A computational theory for classification of natural biosonar targets is developed based on the properties of an example stimulus ensemble. An extensive set of echoes (84 800) from four different foliages was transcribed into a spike code…

Biological Physics · Physics 2007-05-23 Rolf Mueller

We consider the information transmission problem in neurons and its possible implications for learning in neural networks. Our approach is based on recent developments in statistical physics and complexity science. Combining sensory…

Neurons and Cognition · Quantitative Biology 2025-09-30 Siddharth Kackar

The mushroom body of the fruit fly brain is one of the best studied systems in neuroscience. At its core it consists of a population of Kenyon cells, which receive inputs from multiple sensory modalities. These cells are inhibited by the…

Computation and Language · Computer Science 2021-03-16 Yuchen Liang , Chaitanya K. Ryali , Benjamin Hoover , Leopold Grinberg , Saket Navlakha , Mohammed J. Zaki , Dmitry Krotov

Spike time response curves (STRC's) are used to study the influence of synaptic stimuli on the firing times of a neuron oscillator without the assumption of weak coupling. They allow us to approximate the dynamics of synchronous state in…

Neurons and Cognition · Quantitative Biology 2013-04-24 Sachin S. Talathi , Dong-Uk Hwang , Abraham Miliotis , Paul R. Carney , William L. Ditto

Continual learning in computational systems is challenging due to catastrophic forgetting. We discovered a two layer neural circuit in the fruit fly olfactory system that addresses this challenge by uniquely combining sparse coding and…

Machine Learning · Computer Science 2021-12-23 Yang Shen , Sanjoy Dasgupta , Saket Navlakha

A mechanism is proposed for increasing selectivity of olfactory bulb projection neurons as compared to the olfactory receptor neurons, which could operate under low odor concentration, when the lateral inhibition mechanism becomes…

Neurons and Cognition · Quantitative Biology 2021-11-09 Alexander Vidybida

We present a theoretical study aiming at model fitting for sensory neurons. Conventional neural network training approaches are not applicable to this problem due to lack of continuous data. Although the stimulus can be considered as a…

Neurons and Cognition · Quantitative Biology 2017-09-28 R. Ozgur Doruk , Kechen Zhang

In a generic neuron model, we present the linear response theory for the firing rate in response to both time dependent input currents and noise amplitudes. In both cases the signal transmission is strongly attenuated for frequencies above…

Biological Physics · Physics 2007-05-23 Bjoern Naundorf , Theo Geisel , Fred Wolf

This article provides a background and descriptive analysis of insect memory and the coding of olfactory sensation in Drosophila, presenting graphs and summary statistics from a large dataset of neurons and synapses that was recently made…

Neurons and Cognition · Quantitative Biology 2022-09-07 Chris Rohlfs

Achieving fast and reliable temporal signal encoding is crucial for low-power, always-on systems. While current spike-based encoding algorithms rely on complex networks or precise timing references, simple and robust encoding models can be…

Neural and Evolutionary Computing · Computer Science 2025-04-23 Filippo Costa , Chiara De Luca

Neuromorphic processors that implement Spiking Neural Networks (SNNs) using mixed-signal analog/digital circuits represent a promising technology for closed-loop real-time processing of biosignals. As in biology, to minimize power…

Signal Processing · Electrical Eng. & Systems 2023-09-29 Rachel Sava , Elisa Donati , Giacomo Indiveri

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

The olfactory system employs responses of an ensemble of odorant receptors (ORs) to sense molecules and to generate olfactory percepts. Here we hypothesized that ORs can be viewed as 3D spatial filters that extract molecular features…

Machine Learning · Computer Science 2024-12-13 Sergey Shuvaev , Khue Tran , Khristina Samoilova , Cyrille Mascart , Alexei Koulakov

Biological neurons exhibit diverse temporal spike patterns, which are believed to support efficient, robust, and adaptive neural information processing. While models such as Izhikevich can replicate a wide range of these firing dynamics,…

Neural and Evolutionary Computing · Computer Science 2025-05-08 Ayana Moshruba , Hamed Poursiami , Maryam Parsa

Neurons process sensory stimuli efficiently, showing sparse yet highly variable ensemble spiking activity involving structured higher-order interactions. Notably, while neural populations are mostly silent, they occasionally exhibit highly…

Neurons and Cognition · Quantitative Biology 2025-07-17 Ulises Rodríguez-Domínguez , Hideaki Shimazaki

During slow-wave sleep, the brain produces traveling waves of slow oscillations (SOs; $\leq 2$ Hz), characterized by the propagation of alternating high- and low-activity states. The question of internal mechanisms that modulate traveling…

Adaptation and Self-Organizing Systems · Physics 2025-10-16 Ronja Strömsdörfer , Klaus Obermayer

Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…

Neurons and Cognition · Quantitative Biology 2017-12-18 Clemens Korndörfer , Ekkehard Ullner , Jordi García-Ojalvo , Gordon Pipa

Sensory systems take continuously varying stimuli as their input and encode features relevant for the organism's survival into a sequence of action potentials - spike trains. The full dynamic range of complex dynamical inputs has to be…

Neurons and Cognition · Quantitative Biology 2011-03-03 Ingrid M. Esteves , Nelson M. Fernandes , Roland Köberle