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We have developed a two dimensional stochastic molecular dynamics model for the description of intra cellular collective motion of bio motors, in particular Kinesins, on a microtubular track. The model is capable or reproducing the…

Soft Condensed Matter · Physics 2010-06-22 Yousef Jamali , M. Ebrahim Foulaadvand , H. Rafii Tabar

On the basis of the transport features and experimental phenomena observed in studies of molecular motors, we proposea double-temperature ratchet model of coupled motors to reveal the dynamical mechanism of cooperative transport of motors…

Classical Physics · Physics 2017-02-24 Chen-pu Li , Hong-bin Chen , Zhi-gang Zheng

A generalized optimal velocity model is analyzed, where the optimal velocity function depends not only on the headway of each car but also the headway of the immediately preceding one. The stability condition of the model is derived by…

Pattern Formation and Solitons · Physics 2009-11-07 Shiro Sawada

Synthetic nanoscale complexes capable of mechanical movement are often studied theoretically using discrete-state models that involve instantaneous transitions between metastable states. A number of general results have been derived within…

Statistical Mechanics · Physics 2012-12-21 Dibyendu Mandal , Christopher Jarzynski

Bacterial flagellar motor (BFM) is one of the ion-driven molecular machines, which drives the rotation of flagellar filaments and enable bacteria to swim in viscous solutions. Understanding its mechanism is one challenge in biophysics.…

Biological Physics · Physics 2015-03-06 Yunxin Zhang

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

Statistical Mechanics · Physics 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

We study the influence of filament elasticity on the motion of collective molecular motors. It is found that for a backbone flexibility exceeding a characteristic value (motor stiffness divided through the mean displacement between attached…

Soft Condensed Matter · Physics 2007-05-23 Andrej Vilfan , Erwin Frey , Franz Schwabl

We discover a new type of nonequilibrium phase transition in a model of chromatin dynamics, which accounts for the coherent motions that have been observed in experiment. The coherent motion is due to the long-range cooperation of molecular…

Soft Condensed Matter · Physics 2023-07-27 Iraj Eshghi , Alexanda Zidovska , Alexander Y. Grosberg

A ratchet model for coupled Brownian motors, inspired by the motion of individual two-headed molecular motors on cytoskeletal filaments, is proposed. Such motors are modeled as two elastically coupled Brownian particles, each of which moves…

Soft Condensed Matter · Physics 2009-11-07 Debasis Dan , A. M. Jayannavar , Gautam I. Menon

Molecular machines consist of either a single protein or a macromolecular complex composed of protein and RNA molecules. Just like their macroscopic counterparts, each of these nano-machines has an engine that "transduces" input energy into…

Biological Physics · Physics 2012-03-15 Debashish Chowdhury

A model of an autonomous isothermal Brownian motor with an internal propulsion mechanism is considered. The motor is a Brownian particle which is semi-transparent for molecules of surrounding ideal gas. Molecular passage through the…

Statistical Mechanics · Physics 2015-06-15 A. V. Plyukhin

Torque is ubiquitous in many molecular systems, including collisions, chemical reactions, vibrations, electronic excitations and especially rotor molecules. We present a straightforward theoretical method based on forces acting on atoms and…

Chemical Physics · Physics 2016-11-23 Rui-Qin Zhang , Yan-Ling Zhao , Fei Qi , Klaus Hermann , Michel A. Van Hove

Intracellular transport is an essential function in eucaryotic cells, facilitated by motor proteins - proteins converting chemical energy into kinetic energy. It is known that motor proteins work in teams enabling unidirectional and…

Subcellular Processes · Quantitative Biology 2016-03-29 Shreyas Bhaban , Donatello Materassi , Mingang Li , Thomas Hays , Murti Salapaka

For a single enzyme or molecular motor operating in an aqueous solution of non-equilibrated solute concentrations, a thermodynamic description is developed on the level of an individual trajectory of transitions between states. The concept…

Statistical Mechanics · Physics 2012-05-21 Udo Seifert

Polar polymer activity is a fundamental mechanism behind a large number of cellular dynamical processes. The number and location of the active sites on the polymer backbone play a central role in their dynamics and conformational…

Soft Condensed Matter · Physics 2025-03-25 Surabhi Jaiswal , Prithwiraj Maity , Snigdha Thakur , Marisol Ripoll

The traffic of molecular motors through open tube-like compartments is studied using lattice models. These models exhibit boundary-induced phase transitions related to those of the asymmetric simple exclusion process (ASEP) in one…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

Theoretical analysis, which maps single molecule time trajectories of a molecular motor onto unicyclic Markov processes, allows us to evaluate the heat dissipated from the motor and to elucidate its dependence on the mean velocity and…

Subcellular Processes · Quantitative Biology 2017-04-05 Wonseok Hwang , Changbong Hyeon

While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

Biological Physics · Physics 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho

A two-dimensional cellular automaton model of traffic flow with open boundaries are investigated by computer simulations. The outflow of cars from the system and the average velocity are investigated. The time sequences of the outflow and…

adap-org · Physics 2009-10-28 Shin-ichi Tadaki

We propose a mean-field model of intermittent particle transport, where a particle may be in one of two phases: the first is an active (ballistic) phase, when a particle runs with constant velocity in some direction, and the second is a…

Statistical Mechanics · Physics 2017-10-24 Sergey A. Rukolaine