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For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…

Biological Physics · Physics 2020-04-03 Lucas da Costa Campos , Raphael Hornung , Gerhard Gompper , Jens Elgeti , Svenja Caspers

We propose a topological framework for memory and inference grounded in the structure of spike-timing dynamics, persistent homology, and the Context-Content Uncertainty Principle (CCUP). Starting from the observation that polychronous…

Neurons and Cognition · Quantitative Biology 2025-08-19 Xin Li

We study a simplified model of the representation of colors in the primate primary cortical visual area V1. The model is described by an initial value problem related to a Hammerstein equation. The solutions to this problem represent the…

Neurons and Cognition · Quantitative Biology 2022-09-16 Olivier D. Faugeras , Anna Song , Romain Veltz

Rotation-invariance is a desired property of machine-learning models for medical image analysis and in particular for computational pathology applications. We propose a framework to encode the geometric structure of the special Euclidean…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Maxime W. Lafarge , Erik J. Bekkers , Josien P. W. Pluim , Remco Duits , Mitko Veta

In psychology and neuroscience it is common to describe cognitive systems as input/output devices where perceptual and motor functions are implemented in a purely feedforward, open-loop fashion. On this view, perception and action are often…

Neurons and Cognition · Quantitative Biology 2022-03-10 Manuel Baltieri , Christopher L. Buckley

Inverse optimal control can be used to characterize behavior in sequential decision-making tasks. Most existing work, however, is limited to fully observable or linear systems, or requires the action signals to be known. Here, we introduce…

Machine Learning · Computer Science 2023-10-31 Dominik Straub , Matthias Schultheis , Heinz Koeppl , Constantin A. Rothkopf

This paper investigates the online estimation of neural activity within the primary visual cortex (V1) in the framework of observability theory. We focus on a low-dimensional neural fields modeling hypercolumnar activity to describe…

Optimization and Control · Mathematics 2024-03-05 Adel Malik Annabi , Dario Prandi , Jean-Baptiste Pomet , Ludovic Sacchelli

By building on our earlier work, we establish uncertainty principles in terms of Heisenberg inequalities and of the ambiguity functions associated with magnetic structures on certain coadjoint orbits of infinite-dimensional Lie groups.…

Mathematical Physics · Physics 2015-05-13 Ingrid Beltita , Daniel Beltita

The uncertainty principle, originally formulated by Heisenberg, dramatically illustrates the difference between classical and quantum mechanics. The principle bounds the uncertainties about the outcomes of two incompatible measurements,…

Quantum Physics · Physics 2011-03-02 Mario Berta , Matthias Christandl , Roger Colbeck , Joseph M. Renes , Renato Renner

Hierarchies feature prominently in anatomical accounts of cortical organisation. An open question is which computational (algorithmic) processes are implemented by these hierarchies. One renowned hypothesis is that cortical hierarchies…

Neurons and Cognition · Quantitative Biology 2017-09-08 Andreea O. Diaconescu , Vladimir Litvak , Christoph Mathys , Lars Kasper , Karl J. Friston , Klaas E. Stephan

Physics-Informed Neural Networks (PINNs) have emerged as a powerful framework for solving PDEs, yet existing uncertainty quantification (UQ) approaches for PINNs generally lack rigorous statistical guarantees. In this work, we bridge this…

Machine Learning · Computer Science 2025-09-18 Yifan Yu , Cheuk Hin Ho , Yangshuai Wang

When the motion of a motile cell is observed closely, it appears erratic, and yet the combination of nonequilibrium forces and surfaces can produce striking examples of organization in microbial systems. While most of our current…

In this work, an analysis of the performance of different Variational Quantum Circuits is presented, investigating how it changes with respect to entanglement topology, adopted gates, and Quantum Machine Learning tasks to be performed. The…

Quantum Physics · Physics 2025-09-22 Marco Mordacci , Michele Amoretti

Quantum mechanics provides a statistical description about nature, and thus would be incomplete if its statistical predictions could not be accounted for by some realistic models with hidden variables. There are, however, two powerful…

Quantum Physics · Physics 2012-10-04 Xi Kong , Mingjun Shi , Fazhan Shi , Pengfei Wang , Pu Huang , Qi Zhang , Chenyong Ju , Changkui Duan , Sixia Yu , Jiangfeng Du

In this paper, we give a double twist to the problem of planning under uncertainty. State-of-the-art planners seek to minimize the localization uncertainty by only considering the geometric structure of the scene. In this paper, we argue…

Robotics · Computer Science 2017-02-13 Gabriele Costante , Christian Forster , Jeffrey Delmerico , Paolo Valigi , Davide Scaramuzza

Developing and fielding complex systems requires proof that they are reliably correct with respect to their design and operating requirements. Especially for autonomous systems which exhibit unanticipated emergent behavior, fully…

Software Engineering · Computer Science 2024-02-28 Matthew Litton , Doron Drusinsky , James Bret Michael

Tree-like structures such as retinal images are widely studied in computer-aided diagnosis systems for large-scale screening programs. Despite several segmentation and tracking methods proposed in the literature, there still exist several…

Computer Vision and Pattern Recognition · Computer Science 2017-06-27 Samaneh Abbasi-Sureshjani , Marta Favali , Giovanna Citti , Alessandro Sarti , Bart M. ter Haar Romeny

EM algorithm is a convenient tool for maximum likelihood model fitting when the data are incomplete or when there are latent variables or hidden states. In this review article we explain that EM algorithm is a natural computational scheme…

Methodology · Statistics 2011-04-13 Zhangzhang Si , Haifeng Gong , Song-Chun Zhu , Ying Nian Wu

Recently, Cohen and Glashow pointed out that all known experimental tests of relativistic kinematics are consistent with invariance of physics under the four-parameter subgroup Sim(2) of the Lorentz group. The massive one-particle…

High Energy Physics - Phenomenology · Physics 2008-11-26 JiJi Fan , Walter D. Goldberger , Witold Skiba

The ability to recognize objects despite there being differences in appearance, known as Core Object Recognition, forms a critical part of human perception. While it is understood that the brain accomplishes Core Object Recognition through…

Machine Learning · Computer Science 2020-05-15 Harshvardhan Sikka