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We propose a general and flexible procedure for testing multiple hypotheses about sequential (or streaming) data that simultaneously controls both the false discovery rate (FDR) and false nondiscovery rate (FNR) under minimal assumptions…

Methodology · Statistics 2019-01-14 Jay Bartroff , Jinlin Song

We consider the problem of variable selection in high-dimensional statistical models where the goal is to report a set of variables, out of many predictors $X_1, \dotsc, X_p$, that are relevant to a response of interest. For linear…

Methodology · Statistics 2019-03-20 Adel Javanmard , Hamid Javadi

Conformal novelty detection is a classical machine learning task for which uncertainty quantification is essential for providing reliable results. Recent work has shown that the BH procedure applied to conformal p-values controls the false…

Methodology · Statistics 2026-03-16 Zijun Gao , Etienne Roquain , Daniel Xiang

False discovery rate (FDR) is commonly used for correction for multiple testing in neuroimaging studies. However, when using two-tailed tests, making directional inferences about the results can lead to a vastly inflated error rate, even…

Methodology · Statistics 2025-12-16 Anderson M. Winkler , Paul A. Taylor , Thomas E. Nichols , Chris Rorden

In hypothesis testing, a false discovery occurs when a hypothesis is incorrectly rejected due to noise in the sample. When adaptively testing multiple hypotheses, the probability of a false discovery increases as more tests are performed.…

Machine Learning · Statistics 2020-10-22 Wanrong Zhang , Gautam Kamath , Rachel Cummings

The concept of $k$-FWER has received much attention lately as an appropriate error rate for multiple testing when one seeks to control at least $k$ false rejections, for some fixed $k\ge 1$. A less conservative notion, the $k$-FDR, has been…

Statistics Theory · Mathematics 2009-06-18 Sanat K. Sarkar , Wenge Guo

Simultaneously performing variable selection and inference in high-dimensional models is an open challenge in statistics and machine learning. The increasing availability of vast amounts of variables requires the adoption of specific…

Methodology · Statistics 2025-10-02 Marco Molinari , Magne Thoresen

Modern scientific technology has provided a new class of large-scale simultaneous inference problems, with thousands of hypothesis tests to consider at the same time. Microarrays epitomize this type of technology, but similar situations…

Statistics Theory · Mathematics 2007-11-06 Bradley Efron

We study a discrete-time approximation for solutions of systems of decoupled forward-backward doubly stochastic differential equations (FBDSDEs). Assuming that the coefficients are Lipschitz-continuous, we prove the convergence of the…

Probability · Mathematics 2009-07-14 Auguste Aman

There is a challenge in selecting high-dimensional mediators when the mediators have complex correlation structures and interactions. In this work, we frame the high-dimensional mediator selection problem into a series of hypothesis tests…

Methodology · Statistics 2025-09-16 Runqiu Wang , Ran Dai , Jieqiong Wang , Kah Meng Soh , Ziyang Xu , Mohamed Azzam , Hongying Dai , Cheng Zheng

The mitigation of false positives is an important issue when conducting multiple hypothesis testing. The most popular paradigm for false positives mitigation in high-dimensional applications is via the control of the false discovery rate…

Methodology · Statistics 2018-07-17 Hien D. Nguyen , Yohan Yee , Geoffrey J. McLachlan , Jason P. Lerch

We obtain new quantitative estimates of the vanishing viscosity approximation for time-dependent, degenerate, Hamilton-Jacobi equations that are neither concave nor convex in the gradient and Hessian entries of the form $\partial_t…

Analysis of PDEs · Mathematics 2025-09-16 Alekos Cecchin , Alessandro Goffi

We present a novel necessary and sufficient principle for False Discovery Rate (FDR) control. This e-Partitioning Principle says that a procedure controls FDR if and only if it is a special case of a general e-Partitioning procedure. By…

Statistics Theory · Mathematics 2025-09-15 Jelle Goeman , Rianne de Heide , Aldo Solari

The highly influential two-group model in testing a large number of statistical hypotheses assumes that the test statistics are drawn independently from a mixture of a high probability null distribution and a low probability alternative.…

Methodology · Statistics 2020-12-08 Ruth Heller , Saharon Rosset

We consider a sparse linear regression model with unknown symmetric error under the high-dimensional setting. The true error distribution is assumed to belong to the locally $\beta$-H\"{o}lder class with an exponentially decreasing tail,…

Statistics Theory · Mathematics 2020-09-01 Kyoungjae Lee , Minwoo Chae , Lizhen Lin

In this work, we propose an efficient two-stage algorithm solving a joint problem of correlation detection and partial alignment recovery between two Gaussian databases. Correlation detection is a hypothesis testing problem; under the null…

Information Theory · Computer Science 2023-05-26 Ran Tamir

The traditional approaches to false discovery rate (FDR) control in multiple hypothesis testing are usually based on the null distribution of a test statistic. However, all types of null distributions, including the theoretical,…

Methodology · Statistics 2021-04-13 Kun He , Mengjie Li , Yan Fu , Fuzhou Gong , Xiaoming Sun

The topological gap protocol (TGP) is a statistical test designed to identify a topological phase with high confidence and without human bias. It is used to determine a promising parameter regime for operating topological qubits. The…

Mesoscale and Nanoscale Physics · Physics 2025-04-21 Morteza Aghaee , Zulfi Alam , Mariusz Andrzejczuk , Andrey E. Antipov , Mikhail Astafev , Amin Barzegar , Bela Bauer , Jonathan Becker , Umesh Kumar Bhaskar , Alex Bocharov , Srini Boddapati , David Bohn , Jouri Bommer , Leo Bourdet , Samuel Boutin , Benjamin J. Chapman , Sohail Chatoor , Anna Wulff Christensen , Patrick Codd , William S. Cole , Paul Cooper , Fabiano Corsetti , Ajuan Cui , Andreas Ekefjärd , Saeed Fallahi , Luca Galletti , Geoff Gardner , Deshan Govender , Flavio Griggio , Ruben Grigoryan , Sebastian Grijalva , Sergei Gronin , Jan Gukelberger , Marzie Hamdast , Esben Bork Hansen , Sebastian Heedt , Samantha Ho , Laurens Holgaard , Kevin Van Hoogdalem , Jinnapat Indrapiromkul , Henrik Ingerslev , Lovro Ivancevic , Thomas Jensen , Jaspreet Jhoja , Jeffrey Jones , Konstantin V. Kalashnikov , Ray Kallaher , Rachpon Kalra , Farhad Karimi , Torsten Karzig , Maren Elisabeth Kloster , Christina Knapp , Jonne Koski , Pasi Kostamo , Tom Laeven , Gijs de Lange , Thorvald Larsen , Jason Lee , Kyunghoon Lee , Grant Leum , Kongyi Li , Tyler Lindemann , Matthew Looij , Marijn Lucas , Roman Lutchyn , Morten Hannibal Madsen , Nash Madulid , Michael Manfra , Signe Brynold Markussen , Esteban Martinez , Marco Mattila , Robert McNeil , Ryan V. Mishmash , Gopakumar Mohandas , Christian Mollgaard , Michiel de Moor , Trevor Morgan , George Moussa , Chetan Nayak , William Hvidtfelt Padkær Nielsen , Jens Hedegaard Nielsen , Mike Nystrom , Eoin O'Farrell , Keita Otani , Karl Petersson , Luca Petit , Dima Pikulin , Mohana Rajpalke , Alejandro Alcaraz Ramirez , Katrine Rasmussen , David Razmadze , Yuan Ren , Ken Reneris , Ivan A. Sadovskyy , Lauri Sainiemi , Juan Carlos Estrada Saldaña , Irene Sanlorenzo , Emma Schmidgall , Cristina Sfiligoj , Sarat Sinha , Thomas Soerensen , Patrick Sohr , Tomaš Stankevič , Lieuwe Stek , Eric Stuppard , Henri Suominen , Judith Suter , Sam Teicher , Nivetha Thiyagarajah , Raj Tholapi , Mason Thomas , Emily Toomey , Josh Tracy , Michelle Turley , Shivendra Upadhyay , Ivan Urban , Dmitrii V. Viazmitinov , Dominik Vogel , John Watson , Alex Webster , Joseph Weston , Georg W. Winkler , David J. Van Woerkom , Brian Paquelet Wütz , Chung Kai Yang , Emrah Yucelen , Jesús Herranz Zamorano , Roland Zeisel , Guoji Zheng , Justin Zilke

The recent e-Benjamini-Hochberg (e-BH) procedure for multiple hypothesis testing is known to control the false discovery rate (FDR) under arbitrary dependence between the input e-values. This paper points out an important subtlety when…

Methodology · Statistics 2025-08-06 Hongjian Wang , Sanjit Dandapanthula , Aaditya Ramdas

We compare two models of corporate default by calculating the Jeffreys-Kullback-Leibler divergence between their predicted default probabilities when asset correlations are either high or low. Our main results show that the divergence…

Risk Management · Quantitative Finance 2017-04-05 Sylvia Gottschalk