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Stochastic systems in biology often exhibit substantial variability within and between cells. This variability, as well as having dramatic functional consequences, provides information about the underlying details of the system's behaviour.…

Quantitative Methods · Quantitative Biology 2015-11-09 Iain G. Johnston

Abstraction is a well-known approach to simplify a complex problem by over-approximating it with a deliberate loss of information. It was not considered so far in Answer Set Programming (ASP), a convenient tool for problem solving. We…

Logic in Computer Science · Computer Science 2021-07-01 Zeynep G. Saribatur , Thomas Eiter

We show that two important problems that have applications in computational biology are ASP-complete, which implies that, given a solution to a problem, it is NP-complete to decide if another solution exists. We show first that a variation…

Populations and Evolution · Quantitative Biology 2015-03-17 Maria Luisa Bonet , Simone Linz , Katherine St. John

Accurately determining and classifying the structure of complex networks is the focus of much current research. One class of network of particular interest are metabolic pathways, which have previously been studied from a graph theoretical…

Mathematical Physics · Physics 2012-10-10 Henry Dorrian , Kieran Smallbone , Jon borresen

We develop an algorithm to detect community structure in complex networks. The algorithm is based on spectral methods and takes into account weights and links orientations. Since the method detects efficiently clustered nodes in large…

Disordered Systems and Neural Networks · Physics 2009-11-10 Andrea Capocci , Vito D. P. Servedio , Guido Caldarelli , Francesca Colaiori

A common cause of bugs and vulnerabilities are the violations of usage constraints associated with Application Programming Interfaces (APIs). API misuses are common in software projects, and while there have been techniques proposed to…

Software Engineering · Computer Science 2022-04-22 Hong Jin Kang , David Lo

We tackle the problem of automatically designing concurrent data structure operations given a sequential data structure specification and knowledge about concurrent behavior. Designing concurrent code is a non-trivial task even in simplest…

Programming Languages · Computer Science 2021-09-27 Sarat Chandra Varanasi , Neeraj Mittal , Gopal Gupta

Community detection is an important research topic in complex networks. We present the employment of a genetic algorithm to detect communities in complex networks which is based on optimizing network modularity. It does not need any prior…

Physics and Society · Physics 2007-11-06 Mursel Tasgin , Amac Herdagdelen , Haluk Bingol

Answer Set Programming (ASP) is a popular declarative reasoning and problem solving approach in symbolic AI. Its rule-based formalism makes it inherently attractive for explainable and interpretive reasoning, which is gaining importance…

Artificial Intelligence · Computer Science 2026-01-22 Thomas Eiter , Tobias Geibinger , Zeynep G. Saribatur

Addressing the reproducibility crisis in artificial intelligence through the validation of reported experimental results is a challenging task. It necessitates either the reimplementation of techniques or a meticulous assessment of papers…

Machine Learning · Computer Science 2023-11-14 György Kovács , Attila Fazekas

We present a new approach to enhancing Answer Set Programming (ASP) with Constraint Processing techniques which allows for solving interesting Constraint Satisfaction Problems in ASP. We show how constraints on finite domains can be…

Logic in Computer Science · Computer Science 2010-07-26 Christian Drescher , Toby Walsh

Recent large language models (LLMs) have achieved impressive reasoning milestones but continue to struggle with high computational costs, logical inconsistencies, and sharp performance degradation on high-complexity problems. While…

Artificial Intelligence · Computer Science 2026-05-01 Adam Ishay , Joohyung Lee

We study the asymptotic behavior of multiscale stochastic spatial gene networks. Multiscaling takes into account the difference of abundance between molecules , and captures the dynamic of rare species at a mesoscopic level. We introduce an…

Analysis of PDEs · Mathematics 2017-11-17 Arnaud Debussche , Mac Jugal Nguepedja Nankep

Performance testing in large-scale database systems like SAP HANA is a crucial yet labor-intensive task, involving extensive manual analysis of thousands of measurements, such as CPU time and elapsed time. Manual maintenance of these…

Databases · Computer Science 2024-08-23 Zhan Lyu , Thomas Bach , Yong Li , Nguyen Minh Le , Lars Hoemke

Traditional Answer Set Programming (ASP) rests upon one-shot solving. A logic program is fed into an ASP system and its stable models are computed. The high practical relevance of dynamic applications led to the development of multi-shot…

Programming Languages · Computer Science 2015-11-05 Martin Gebser , Phillip Obermeier , Torsten Schaub

We introduce AutoSpec, a neural network framework for discovering iterative spectral algorithms for large-scale numerical linear algebra and numerical optimization. Our self-supervised models adapt to input operators using coarse spectral…

Machine Learning · Computer Science 2026-02-11 Zihang Liu , Oleg Balabanov , Yaoqing Yang , Michael W. Mahoney

Answer set programs in practice are often subject to change. This can lead to inconsistencies in the modified program due to conflicts between rules which are the results of the derivation of strongly complementary literals. To facilitate…

Logic in Computer Science · Computer Science 2023-08-31 Andre Thevapalan , Gabriele Kern-Isberner

Examining logical inconsistencies among multiple statements (such as collections of sentences or question-answer pairs) is a crucial challenge in machine learning, particularly for ensuring the safety and reliability of models. Traditional…

Machine Learning · Computer Science 2026-01-23 Mooho Song , Hyeryung Son , Jay-Yoon Lee

The response of complex networks to perturbations is of utmost importance in areas as diverse as ecosystem management, emergency response, and cell reprogramming. A fundamental property of networks is that the perturbation of one node can…

Molecular Networks · Quantitative Biology 2011-05-20 Sean P. Cornelius , William L. Kath , Adilson E. Motter

Network inference approaches are now widely used in biological applications to probe regulatory relationships between molecular components such as genes or proteins. Many methods have been proposed for this setting, but the connections and…

Applications · Statistics 2014-06-03 Chris. J. Oates , Sach Mukherjee
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