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Related papers: Dynamics of Dengue epidemics using optimal control

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This paper proposes a feedback design that effectively copes with uncertainties for reliable epidemic monitoring and control. There are several optimization-based methods to estimate the parameters of an epidemic model by utilizing past…

Optimization and Control · Mathematics 2023-04-06 Muhammad Umar B. Niazi , Philip E. Paré , Karl H. Johansson

We propose an epidemic model for the spread of vector-borne diseases. The model, which is built extending the classical susceptible-infected-susceptible model, accounts for two populations -- humans and vectors -- and for cross-contagion…

Systems and Control · Electrical Eng. & Systems 2025-10-21 Lorenzo Zino , Alessandro Casu , Alessandro Rizzo

We study an optimal control problem for a stochastic model of tumour growth with drug application. This model consists of three stochastic hyperbolic equations describing the evolution of tumour cells. It also includes two stochastic…

Optimization and Control · Mathematics 2024-08-30 Sakine Esmaili , M. R. Eslahchi , Delfim F. M. Torres

Reliable and timely dengue predictions provide actionable lead time for targeted vector control and clinical preparedness, reducing preventable diseases and health-system costs in at-risk communities. Dengue forecasting often relies on…

Applications · Statistics 2025-12-01 Saman Hosseini , Lee W. Cohnstaedt , Caterina Scoglio

In this chapter, we focus on the problem of containing the spread of diseases taking place in both temporal and adaptive networks (i.e., networks whose structure `adapts' to the state of the disease). We specifically focus on the problem of…

Social and Information Networks · Computer Science 2019-03-19 Masaki Ogura , Victor M. Preciado

Dengue fever presents a substantial challenge in developing countries where sanitation infrastructure is inadequate. The absence of comprehensive healthcare systems exacerbates the severity of dengue infections, potentially leading to…

Dengue transmission is rapidly expanding beyond its historical tropical range, raising concerns about how climate change may alter the collective dynamics of epidemics. While most studies focus on transmission risk, much less is known about…

Physics and Society · Physics 2026-05-11 Enrique C. Gabrick , Antonio M. Batista , Iberê L. Caldas , Jürgen Kurths , Maíra Aguiar

We present an epidemiological model for vector-borne diseases that includes within-host viral load and antibody dynamics using structured transport equations. By incorporating the internal dynamics into the infected and recovered host…

Analysis of PDEs · Mathematics 2026-05-26 Paulo Amorim , Maria Soledad Aronna , Debora de Oliveira Medeiros

We present a dynamic model for the optimal control problem (OCP) of hydrogen blending into natural gas pipeline networks subject to inequality constraints. The dynamic model is derived using the first principles partial differential…

Optimization and Control · Mathematics 2024-02-27 Saif R. Kazi , Kaarthik Sundar , Anatoly Zlotnik

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

Populations and Evolution · Quantitative Biology 2021-03-12 Afroza Shirin , Yen Ting Lin , Francesco Sorrentino

Dengue represents a serious public health problem in tropical and subtropical regions worldwide. The number of dengue cases and its geographical expansion has increased in recent decades, driven mostly after by social and environmental…

Populations and Evolution · Quantitative Biology 2021-07-14 Yury E. García , Luis A. Barboza , Fabio Sanchez , Paola Vásquez , Juan G. Calvo

Recently, the RIDL-SIT technology has been field-tested for control of Aedes aegypti. The technique consists of releasing genetically modified mosquitoes carrying a "lethal gene". In 2016 the World Health Organisation (WHO) and the…

Populations and Evolution · Quantitative Biology 2020-06-02 Mario A. Natiello , Hernán G. Solari

We characterize the optimal control for a class of singular stochastic control problems as the unique solution to a related Skorokhod reflection problem. The considered optimization problems concern the minimization of a discounted cost…

Optimization and Control · Mathematics 2023-05-22 Jodi Dianetti , Giorgio Ferrari

We study a resource allocation problem for containing an infectious disease in a metapopulation subject to resource uncertainty. We propose a two-stage model where the policy maker seeks to allocate resources in both stages where the second…

Optimization and Control · Mathematics 2020-06-03 Ceyda Yaba Best , Amin Khademi , Burak Eksioglu

Motivated by the applications, a class of optimal control problems is investigated, where the goal is to influence the behavior of a given population through another controlled one interacting with the first. Diffusive terms accounting for…

Optimization and Control · Mathematics 2023-03-10 Stefano Almi , Marco Morandotti , Francesco Solombrino

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

Populations and Evolution · Quantitative Biology 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

Dengue is a life threatening disease prevalent in several developed as well as developing countries like India.In this paper we discuss various algorithm approaches of data mining that have been utilized for dengue disease prediction. Data…

Computers and Society · Computer Science 2015-02-19 Kashish Ara Shakil , Shadma Anis , Mansaf Alam

Cell heterogeneity plays an important role in patient responses to drug treatments. In many cancers, it is associated with poor treatment outcomes. Many modern drug combination therapies aim to exploit cell heterogeneity, but determining…

Quantitative Methods · Quantitative Biology 2025-02-18 Simon F. Martina-Perez , Samuel W. S. Johnson , Rebecca M. Crossley , Jennifer C. Kasemeier , Paul M. Kulesa , Ruth E. Baker

Mosquito-borne diseases cause significant public health burden, mostly in tropical and sub-tropical regions, and are widely emerging or re-emerging in areas where previously absent. Understanding, predicting, and mitigating the spread of…

Quantitative Methods · Quantitative Biology 2017-01-19 Carrie A. Manore , Kyle S. Hickmann , James M. Hyman , Ivo M. Foppa , Justin K. Davis , Dawn M. Wesson , Christopher N. Mores

A Caputo fractional-order mathematical model for the transmission dynamics of tuberculosis (TB) was recently proposed in [Math. Model. Nat. Phenom. 13 (2018), no. 1, Art. 9]. Here, a sensitivity analysis of that model is done, showing the…

Optimization and Control · Mathematics 2019-08-12 Silverio Rosa , Delfim F. M. Torres
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