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Mathematical modelling allows us to concisely describe fundamental principles in biology. Analysis of models can help to both explain known phenomena, and predict the existence of new, unseen behaviours. Model analysis is often a complex…

Quantitative Methods · Quantitative Biology 2020-08-13 Mark Blyth , Ludovic Renson , Lucia Marucci

Using bioimaging technology, biologists have attempted to identify and document analytical interpretations that underlie biological phenomena in biological cells. Theoretical biology aims at distilling those interpretations into knowledge…

Neuromorphic Computing implemented in photonic hardware is one of the most promising routes towards achieving machine learning processing at the picosecond scale, with minimum power consumption. In this work, we present a new concept for…

Emerging Technologies · Computer Science 2022-11-01 K. Sozos , A. Bogris , P. Bienstman , G. Sarantoglou , S. Deligiannidis , C. Mesaritakis

Mathematical modelling is a cornerstone of computational biology. While mechanistic models might describe the interactions of interest of a system, they are often difficult to study. On the other hand, abstract models might capture key…

Dynamical Systems · Mathematics 2025-05-01 Lucas Jesus Morales-Moya

Nonlinear systems, transforming an input signal into a high-dimensional output feature space, can be used for non-conventional computing. This approach, however, requires a change of system parameters during training rather than…

Optics · Physics 2025-05-30 S. Bogdanov , E. Manuylovich , S. K. Turitsyn

In this article, we review a class of neuro-mimetic computational models that we place under the label of spiking predictive coding. Specifically, we review the general framework of predictive processing in the context of neurons that emit…

Neurons and Cognition · Quantitative Biology 2024-09-10 Antony W. N'dri , William Gebhardt , Céline Teulière , Fleur Zeldenrust , Rajesh P. N. Rao , Jochen Triesch , Alexander Ororbia

Physics-informed neural networks exploit the existing models of the underlying physical systems to generate higher accuracy results with fewer data. Such approaches can help drastically reduce the computation time and generate a good…

Systems and Control · Electrical Eng. & Systems 2021-09-28 Rahul Nellikkath , Spyros Chatzivasileiadis

Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to understand biological processes and systems is therefore to confront our ideas and hypotheses with data using statistical methods to determine the…

Quantitative Methods · Quantitative Biology 2022-06-22 Sean T. Vittadello , Michael P. H. Stumpf

Since the turn of the millennium, computational modelling of biological systems has evolved remarkably and sees matured use spanning basic and clinical research. While the topic of the peri-millennial debate about the virtues and…

Quantitative Methods · Quantitative Biology 2025-08-05 Axel Loewe , Peter J. Hunter , Peter Kohl

Computational multiscale modeling encompasses a wide range of end-products and a great number of technological applications. This paper provides an overview of the computational multiscale modeling approach based on the utilization of MBN…

Computational Physics · Physics 2021-07-23 Alexey V. Verkhovtsev , Ilia A. Solov'yov , Andrey V. Solov'yov

Accurate molecular force fields are of paramount importance for the efficient implementation of molecular dynamics techniques at large scales. In the last decade, machine learning methods have demonstrated impressive performances in…

Quantum Physics · Physics 2022-07-22 Oriel Kiss , Francesco Tacchino , Sofia Vallecorsa , Ivano Tavernelli

The rise of foundation models -- large, pretrained machine learning models that can be finetuned to a variety of tasks -- has revolutionized the fields of natural language processing and computer vision. In high-energy physics, the question…

High Energy Physics - Phenomenology · Physics 2026-01-12 Anna Hallin

The introduction of computational models in cardiovascular sciences has been progressively bringing new and unique tools for the investigation of the physiopathology. Together with the dramatic improvement of imaging and measuring devices…

Computational intelligence is broadly defined as biologically-inspired computing. Usually, inspiration is drawn from neural systems. This article shows how to analyze neural systems using information theory to obtain constraints that help…

Neurons and Cognition · Quantitative Biology 2018-05-11 Michael Wibral , Joseph T. Lizier , Viola Priesemann

Future quantum computers are anticipated to be able to perform simulations of quantum many-body systems and quantum field theories that lie beyond the capabilities of classical computation. This will lead to new insights and predictions for…

Nuclear Theory · Physics 2023-12-14 Martin J. Savage

We review the theory of neural networks, as it has emerged in the last ten years or so within the physics community, emphasizing questions of biological relevance over those of importance in mathematical statistics and machine learning…

Disordered Systems and Neural Networks · Physics 2008-02-03 Heinz Horner , Reimer Kuehn

Over the past decade, deep learning models have exhibited considerable advancements, reaching or even exceeding human-level performance in a range of visual perception tasks. This remarkable progress has sparked interest in applying deep…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yulin Wang , Yizeng Han , Chaofei Wang , Shiji Song , Qi Tian , Gao Huang

Optical forces are often calculated by discretizing the trapping light beam into a set of rays and using geometrical optics to compute the exchange of momentum. However, the number of rays sets a trade-off between calculation speed and…

Building machines that learn and think like humans is essential not only for cognitive science, but also for computational neuroscience, whose ultimate goal is to understand how cognition is implemented in biological brains. A new cognitive…

Artificial Intelligence · Computer Science 2017-11-15 Nikolaus Kriegeskorte , Robert M. Mok

Deep learning, computational neuroscience, and cognitive science have overlapping goals related to understanding intelligence such that perception and behaviour can be simulated in computational systems. In neuroimaging, machine learning…

Neural and Evolutionary Computing · Computer Science 2018-10-23 Jessica A. F. Thompson , Yoshua Bengio , Elia Formisano , Marc Schönwiesner