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Automated lobar segmentation allows regional evaluation of lung disease and is important for diagnosis and therapy planning. Advanced statistical workflows permitting such evaluation is a needed area within respiratory medicine; their…
Breast cancer is becoming pervasive with each passing day. Hence, its early detection is a big step in saving the life of any patient. Mammography is a common tool in breast cancer diagnosis. The most important step here is classification…
Endomicroscopy is indispensable for minimally invasive diagnostics in clinical practice. For optical keyhole monitoring of surgical interventions, high-resolution fiber endoscopic imaging is considered to be very promising, especially in…
The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…
Lymphoma diagnosis, particularly distinguishing between subtypes, is critical for effective treatment but remains challenging due to the subtle morphological differences in histopathological images. This study presents a novel hybrid deep…
While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…
We explore the problem of classification within a medical image data-set based on a feature vector extracted from the deepest layer of pre-trained Convolution Neural Networks. We have used feature vectors from several pre-trained…
The purpose of this study was to develop a fully-automated segmentation algorithm, robust to various density enhancing lung abnormalities, to facilitate rapid quantitative analysis of computed tomography images. A polymorphic training…
Lung diseases including infections such as Pneumonia, Tuberculosis, and novel Coronavirus (COVID-19), together with Lung Cancer are significantly widespread and are, typically, considered life threatening. In particular, lung cancer is…
Algorithmic detection of facial palsy offers the potential to improve current practices, which usually involve labor-intensive and subjective assessments by clinicians. In this paper, we present a multimodal fusion-based deep learning model…
Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…
Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential for detection and staging, has limitations in distinguishing benign from malignant lesions…
Glomerulosclerosis, interstitial fibrosis, and tubular atrophy (IFTA) are histologic indicators of irrecoverable kidney injury. In standard clinical practice, the renal pathologist visually assesses, under the microscope, the percentage of…
Cancer treatments are known to introduce cardiotoxicity, negatively impacting outcomes and survivorship. Identifying cancer patients at risk of heart failure (HF) is critical to improving cancer treatment outcomes and safety. This study…
An essential aspect of texture analysis is the extraction of features that describe the distribution of values in local, spatial regions. We present a localized histogram layer for artificial neural networks. Instead of computing global…
Classification of damages in honeycomb composite sandwich structure (HCSS) is important to decide remedial actions. However, previous studies have only detected damages using deviations of monitoring signal from healthy (baseline) using a…
Quantum Machine Learning (QML) is a red-hot field that brings novel discoveries and exciting opportunities to resolve, speed up, or refine the analysis of a wide range of computational problems. In the realm of biomedical research and…
In this paper, a logo classification system based on the appearance of logo images is proposed. The proposed classification system makes use of global characteristics of logo images for classification. Color, texture, and shape of a logo…
The rich chemical information from tissue metabolomics provides a powerful means to elaborate tissue physiology or tumor characteristics at cellular and tumor microenvironment levels. However, the process of obtaining such information…
Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…