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Graph neural networks (GNNs) have recently emerged as a promising approach for solving the Boolean Satisfiability Problem (SAT), offering potential alternatives to traditional backtracking or local search SAT solvers. However, despite the…

Machine Learning · Computer Science 2024-05-14 Zhaoyu Li , Jinpei Guo , Xujie Si

We propose a data-driven algorithm for numerical invariant synthesis and verification. The algorithm is based on the ICE-DT schema for learning decision trees from samples of positive and negative states and implications corresponding to…

Programming Languages · Computer Science 2022-07-11 Ahmed Bouajjani , Wael-Amine Boutglay , Peter Habermehl

We consider a problem of data integration. Consider determining which genes affect a disease. The genes, which we call predictor objects, can be measured in different experiments on the same individual. We address the question of finding…

Machine Learning · Statistics 2016-10-04 Xin Gao , Raymond J. Carroll

Gene regulation is a series of processes that control gene expression and its extent. The connections among genes and their regulatory molecules, usually transcription factors, and a descriptive model of such connections, are known as gene…

Molecular Networks · Quantitative Biology 2017-04-24 Yasser Abduallah , Turki Turki , Kevin Byron , Zongxuan Du , Miguel Cervantes-Cervantes , Jason T. L. Wang

Machine learning approaches to solving Boolean Satisfiability (SAT) aim to replace handcrafted heuristics with learning-based models. Graph Neural Networks have emerged as the main architecture for SAT solving, due to the natural graph…

Machine Learning · Computer Science 2026-02-10 Saku Peltonen , Roger Wattenhofer

In this paper, we conduct theoretical analyses on inferring the structure of gene regulatory networks. Depending on the experimental method and data type, the inference problem is classified into 20 different scenarios. For each scenario,…

Molecular Networks · Quantitative Biology 2022-02-18 Yue Wang , Zikun Wang

A critical factor in trustworthy machine learning is to develop robust representations of the training data. Only under this guarantee methods are legitimate to artificially generate data, for example, to counteract imbalanced datasets or…

Machine Learning · Computer Science 2024-12-12 Leon Scharwächter , Sebastian Otte

Grammatical inference consists in learning a formal grammar (as a set of rewrite rules or a finite state machine). We are concerned with learning Nondeterministic Finite Automata (NFA) of a given size from samples of positive and negative…

Artificial Intelligence · Computer Science 2021-07-14 Frédéric Lardeux , Eric Monfroy

As machine learning is increasingly used to help make decisions, there is a demand for these decisions to be explainable. Arguably, the most explainable machine learning models use decision rules. This paper focuses on decision sets, a type…

Artificial Intelligence · Computer Science 2020-07-31 Jinqiang Yu , Alexey Ignatiev , Peter J. Stuckey , Pierre Le Bodic

Delays in protein synthesis cause a confounding effect when constructing Gene Regulatory Networks (GRNs) from RNA-sequencing time-series data. Accurate GRNs can be very insightful when modelling development, disease pathways, and drug…

Molecular Networks · Quantitative Biology 2020-10-07 Jacob Moss , Pietro Lió

Markov State Models (MSMs) are a powerful framework to reproduce the long-time conformational dynamics of biomolecules using a set of short Molecular Dynamics (MD) simulations. However, precise kinetics predictions of MSMs heavily rely on…

Biomolecules · Quantitative Biology 2018-06-27 Qihua Chen , Jiangyan Feng , Shriyaa Mittal , Diwakar Shukla

A common goal in modern biostatistics is to form a biomarker signature from high dimensional gene expression data that is predictive of some outcome of interest. After learning this biomarker signature, an important question to answer is…

Statistics Theory · Mathematics 2015-10-05 Samuel M. Gross , Jonathan Taylor , Robert Tibshirani

We propose a genetic algorithm powered evolution (GAPE) method to create deep learning solutions for energy and position estimation for reactor antineutrino interactions in the Precision Reactor Oscillation and Spectrum Experiment…

Gene Regulatory Network (GRN) plays an important role in knowing insight of cellular life cycle. It gives information about at which different environmental conditions genes of particular interest get over expressed or under expressed.…

Computational Engineering, Finance, and Science · Computer Science 2013-10-10 Chanda Panse , Dr. Manali Kshirsagar

Identifying anomalies refers to detecting samples that do not resemble the training data distribution. Many generative models have been used to find anomalies, and among them, generative adversarial network (GAN)-based approaches are…

Machine Learning · Computer Science 2022-01-03 Laya Rafiee Sevyeri , Thomas Fevens

Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…

Methodology · Statistics 2008-09-11 Christine De Mol , Sofia Mosci , Magali Traskine , Alessandro Verri

In this work, we present a quantum circuit model for inferring gene regulatory networks (GRNs). The model is based on the idea of using qubit-qubit entanglement to simulate interactions between genes. We provide preliminary results that…

Emerging Technologies · Computer Science 2022-07-06 Cristhian Roman-Vicharra , James J. Cai

Background: Selecting feature genes to predict phenotypes is one of the typical tasks in analyzing genomics data. Though many general-purpose algorithms were developed for prediction, dealing with highly correlated genes in the prediction…

Applications · Statistics 2022-04-11 Li Xing , Songwan Joun , Kurt Mackay , Mary Lesperance , Xuekui Zhang

Despite theoretical advantages, causal methods for Gene Regulatory Network (GRN) inference from single-cell RNA-seq data consistently fail to match or outperform correlation-based baselines in many realistic benchmarks, a persistent puzzle…

Machine Learning · Computer Science 2026-05-07 Miguel Fernandez-de-Retana , Ruben Sanchez-Corcuera , Unai Zulaika , Aritz Bilbao-Jayo , Aitor Almeida

Click prediction is one of the fundamental problems in sponsored search. Most of existing studies took advantage of machine learning approaches to predict ad click for each event of ad view independently. However, as observed in the…

Information Retrieval · Computer Science 2014-07-29 Yuyu Zhang , Hanjun Dai , Chang Xu , Jun Feng , Taifeng Wang , Jiang Bian , Bin Wang , Tie-Yan Liu