Related papers: Inference of Gene Predictor Set Using Boolean Sati…
Graph neural networks (GNNs) have recently emerged as a promising approach for solving the Boolean Satisfiability Problem (SAT), offering potential alternatives to traditional backtracking or local search SAT solvers. However, despite the…
We propose a data-driven algorithm for numerical invariant synthesis and verification. The algorithm is based on the ICE-DT schema for learning decision trees from samples of positive and negative states and implications corresponding to…
We consider a problem of data integration. Consider determining which genes affect a disease. The genes, which we call predictor objects, can be measured in different experiments on the same individual. We address the question of finding…
Gene regulation is a series of processes that control gene expression and its extent. The connections among genes and their regulatory molecules, usually transcription factors, and a descriptive model of such connections, are known as gene…
Machine learning approaches to solving Boolean Satisfiability (SAT) aim to replace handcrafted heuristics with learning-based models. Graph Neural Networks have emerged as the main architecture for SAT solving, due to the natural graph…
In this paper, we conduct theoretical analyses on inferring the structure of gene regulatory networks. Depending on the experimental method and data type, the inference problem is classified into 20 different scenarios. For each scenario,…
A critical factor in trustworthy machine learning is to develop robust representations of the training data. Only under this guarantee methods are legitimate to artificially generate data, for example, to counteract imbalanced datasets or…
Grammatical inference consists in learning a formal grammar (as a set of rewrite rules or a finite state machine). We are concerned with learning Nondeterministic Finite Automata (NFA) of a given size from samples of positive and negative…
As machine learning is increasingly used to help make decisions, there is a demand for these decisions to be explainable. Arguably, the most explainable machine learning models use decision rules. This paper focuses on decision sets, a type…
Delays in protein synthesis cause a confounding effect when constructing Gene Regulatory Networks (GRNs) from RNA-sequencing time-series data. Accurate GRNs can be very insightful when modelling development, disease pathways, and drug…
Markov State Models (MSMs) are a powerful framework to reproduce the long-time conformational dynamics of biomolecules using a set of short Molecular Dynamics (MD) simulations. However, precise kinetics predictions of MSMs heavily rely on…
A common goal in modern biostatistics is to form a biomarker signature from high dimensional gene expression data that is predictive of some outcome of interest. After learning this biomarker signature, an important question to answer is…
We propose a genetic algorithm powered evolution (GAPE) method to create deep learning solutions for energy and position estimation for reactor antineutrino interactions in the Precision Reactor Oscillation and Spectrum Experiment…
Gene Regulatory Network (GRN) plays an important role in knowing insight of cellular life cycle. It gives information about at which different environmental conditions genes of particular interest get over expressed or under expressed.…
Identifying anomalies refers to detecting samples that do not resemble the training data distribution. Many generative models have been used to find anomalies, and among them, generative adversarial network (GAN)-based approaches are…
Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…
In this work, we present a quantum circuit model for inferring gene regulatory networks (GRNs). The model is based on the idea of using qubit-qubit entanglement to simulate interactions between genes. We provide preliminary results that…
Background: Selecting feature genes to predict phenotypes is one of the typical tasks in analyzing genomics data. Though many general-purpose algorithms were developed for prediction, dealing with highly correlated genes in the prediction…
Despite theoretical advantages, causal methods for Gene Regulatory Network (GRN) inference from single-cell RNA-seq data consistently fail to match or outperform correlation-based baselines in many realistic benchmarks, a persistent puzzle…
Click prediction is one of the fundamental problems in sponsored search. Most of existing studies took advantage of machine learning approaches to predict ad click for each event of ad view independently. However, as observed in the…