Related papers: Ultra-fast treatment plan optimization for volumet…
The dose delivered to the planning target volume by proton beams is highly conformal, sparing organs at risk and normal tissues. New treatment planning systems adapted to spot scanning techniques have been recently proposed to…
We present a method of directly optimizing on deviations in clinical goal values in radiation therapy treatment planning. Using a new mathematical framework in which metrics derived from the dose-volume histogram are regarded as functionals…
A split feasibility formulation for the inverse problem of intensity-modulated radiation therapy (IMRT) treatment planning with dose-volume constraints (DVCs) included in the planning algorithm is presented. It involves a new type of…
The aim of this study is to set up statistical quality control for monitoring of volumetric modulated arc therapy (VMAT) delivery error using machine log data. Eclipse and Clinac iX linac with the RapidArc system (Varian Medical Systems,…
Purpose: To demonstrate the feasibility of fast Monte Carlo (MC) based inverse biological planning for the treatment of head and neck tumors in spot-scanning proton therapy. Methods: Recently, a fast and accurate Graphics Processor Unit…
The first purpose of this paper is to shed some new light on the old question of selecting the number of beams in intensity-modulated radiation therapy (IMRT). The second purpose is to illuminate the related issue of discrete static beam…
This study introduces a novel metric, Plan Aperture Modulation (PAM), developed to quantify the modulation of radiotherapy treatment plans. PAM aims to provide a clear geometric interpretation, addressing the limitations of previous…
High-dose-rate brachytherapy is a tumor treatment method where a highly radioactive source is brought in close proximity to the tumor. In this paper we develop a simulated annealing algorithm to optimize the dwell times at preselected dwell…
Purpose: A promising approach to enable FLASH conformal proton therapy is to passively degrade a single energy layer using a patient-specific range modulator. We propose an innovative method to directly optimize the geometrical…
This study evaluates dynamic conformal arc (DCA) therapy as an alternative to volumetric modulated arc therapy (VMAT) for stereotactic body radiation therapy (SBRT) of lung cancer. The rationale for DCA is lower geometric complexity and…
We apply the superiorization methodology to the intensity-modulated radiation therapy (IMRT) treatment planning problem. In superiorization, linear voxel dose inequality constraints are the fundamental modeling tool within which a…
Current inverse treatment planning methods that optimize both catheter positions and dwell times in prostate HDR brachytherapy use surrogate linear or quadratic objective functions that have no direct interpretation in terms of dose-volume…
With the advancement of treatment modalities in radiation therapy for cancer patients, outcomes have improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would…
Today, intensity-modulated radiation therapy (IMRT) is one of the methods used to treat brain tumors. In conventional treatment planning methods, after identifying planning target volume (PTV), and organs at risk (OARs), and determining the…
We present a method for handling dose constraints as part of a convex programming framework for inverse treatment planning. Our method uniformly handles mean dose, maximum dose, minimum dose, and dose-volume (i.e., percentile) constraints…
In radiation therapy, mathematical methods have been used for optimizing treatment planning for delivery of sufficient dose to the cancerous cells while keeping the dose to critical surrounding structures minimal. This optimization problem…
MPC (Model predictive control)-based motion planning and trajectory generation are essential in applications such as unmanned aerial vehicles, robotic manipulators, and rocket control. However, the real-time implementation of such…
Background: A growing number of cancer patients with brain metastases can benefit from stereotactic radiosurgery (SRS) thanks to recent advances in systemic therapies. With an increasing patient load, single-isocenter treatments on widely…
Background: With the advent of Intensity Modulated Radiotherapy (IMRT) and recently, Volumetric Modulated Arc Therapy (VMAT), treatment planning using Flattening Filter Free (FFF) beams can meet all of the energy requirements in radiation…
As the virtualization of networks continues to attract attention from both industry and academia, the Virtual Network Embedding (VNE) problem remains a focus of researchers. This paper proposes a one-shot, unsplittable flow VNE solution…