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Quantitative modeling has become an essential tool in modern biophysics, driven by advances in both experimental techniques and theoretical frameworks. Powerful high-resolution techniques now provide detailed datasets spanning molecular to…

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

In this paper, we introduce a novel way to represent the interface for two-phase flows with phase change. We combine a level-set method with a Cartesian embedded boundary method and take advantage of both. This is part of an effort to…

Numerical Analysis · Mathematics 2022-12-28 A. Limare , S. Popinet , C. Josserand , Z. Xue , A. Ghigo

This article presents a multi-physics methodology for the numerical simulation of physical systems that involve the non-linear interaction of multi-phase reactive fluids and elastoplastic solids, inducing high strain-rates and high…

Computational Physics · Physics 2021-06-04 Tim Wallis , Philip T. Barton , Nikolaos Nikiforakis

The equations governing the conditions of mechanical equilibrium in fluid membranes subject to bending are revisited thanks to the principle of virtual work. The note proposes systematic tools to obtain the shape equation and the line…

Soft Condensed Matter · Physics 2015-10-19 Henri Gouin

Viscoelastic fluids are a class of fluids that exhibit both viscous and elastic nature. Modelling such fluids requires constitutive equations for the stress, and choosing the most appropriate constitutive relationship can be difficult. We…

Fluid Dynamics · Physics 2024-06-24 Sukirt Thakur , Maziar Raissi , Arezoo M. Ardekani

Vesicular capsules are used to carry biochemicals in biology and liposome technology. Being water-permeable with differing interior and exterior compositions, they are necessarily under osmotic stress. Recent studies have underlined the…

Soft Condensed Matter · Physics 2012-10-10 Emir Haleva , Haim Diamant

Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

Soft Condensed Matter · Physics 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

Cellular membranes are a heterogeneous mix of lipids, proteins and small molecules. Special groupings of saturated lipids and cholesterol form a liquid-ordered phase, known as `lipid rafts,' serving as platforms for signaling, trafficking…

Quantitative Methods · Quantitative Biology 2015-05-13 Tristan S. Ursell , William S. Klug , Rob Phillips

A level-set method is developed for numerically capturing the equilibrium solute-solvent interface that is defined by the recently proposed variational implicit solvent model (Dzubiella, Swanson, and McCammon, Phys. Rev. Lett. {\bf 104},…

Chemical Physics · Physics 2009-11-13 L. -T. Cheng , J. Dzubiella , J. A. McCammon , B. Li

This work presents a rigorous mathematical formulation for topology optimization of a macrostructure undergoing ductile failure. The prediction of ductile solid materials which exhibit dominant plastic deformation is an intriguingly…

Numerical Analysis · Mathematics 2023-03-22 Nima Noii , Hassan Ali Jahangiry , Haim Waisman

Computer simulations of coarse-grained molecular models for amphiphilic systems can provide insight into the the structure of amphiphiles at interfaces. They can help to identify the factors that determine the phase behavior, and they can…

Soft Condensed Matter · Physics 2007-05-23 Friederike Schmid , Dominik Düchs , Olaf Lenz , Claire Loison

We present a phase-field model for the dynamics of the interface between two inmiscible fluids with arbitrary viscosity contrast in a rectangular Hele-Shaw cell. With asymptotic matching techniques we check the model to yield the right…

Soft Condensed Matter · Physics 2009-10-31 R. Folch , J. Casademunt , A. Hernandez-Machado , L. Ramirez-Piscina

Phase separated macromolecules play essential roles in many biological and synthetic systems. Physical characterization of these systems can be challenging because of limited sample volumes, particularly for phase-separated proteins. Here,…

We study dispersive models of fluid flow in viscoelastic vessels, derived in the study of blood flow. The unknowns in the models are the velocity of the fluid in the axial direction and the displacement of the vessel wall from rest. We…

Analysis of PDEs · Mathematics 2022-11-23 Hyeju Kim , David M. Ambrose

Existing hybrid Level Set / Front Tracking methods have been developed for structured meshes and successfully used for efficient and accurate simulations of complex multiphase flows. This contribution extends the capability of hybrid Level…

Computational Physics · Physics 2023-11-22 Tobias Tolle , Dieter Bothe , Tomislav Maric

The flow field generated by a swimming bacterium serves as a fundamental building block for understanding hydrodynamic interactions between bacteria. Although the flow field generated by a force dipole (stresslet) well captures the fluid…

Soft Condensed Matter · Physics 2026-03-27 Yaochen Yang , Daiki Matsunaga , Da Wei , Fanlong Meng

The dynamics and rheology of suspensions of fluid vesicles or red blood cells is investigated by a combination of molecular dynamics and mesoscale hydrodynamics simulations in two dimensions. The vesicle suspension is confined between two…

Soft Condensed Matter · Physics 2013-05-03 A. Lamura , G. Gompper

Fluid flow applications can involve a number of coupled problems. One is the simulation of free-surface flows, which require the solution of a free-boundary problem. Within this problem, the governing equations of fluid flow are coupled…

Numerical Analysis · Mathematics 2015-01-26 Stefanie Elgeti , Henning Sauerland

A variety of models for the membrane-mediated interaction of particles in lipid membranes, mostly well-established in theoretical physics, is reviewed from a mathematical perspective. We provide mathematically consistent formulations in a…

Analysis of PDEs · Mathematics 2016-06-29 Charles M. Elliott , Carsten Gräser , Graham Hobbs , Ralf Kornhuber , Maren-Wanda Wolf
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